دورية أكاديمية
أعرض في EDS

Genotypic Characterization of Uropathogenic Escherichia coli from Companion Animals: Predominance of ST372 in Dogs and Human-Related ST73 in Cats.

التفاصيل البيبلوغرافية
العنوان: Genotypic Characterization of Uropathogenic Escherichia coli from Companion Animals: Predominance of ST372 in Dogs and Human-Related ST73 in Cats.
المؤلفون: Aurich S; Institute of Hygiene and Infectious Diseases of Animals, Faculty of Veterinary Medicine, Justus Liebig University Giessen, 35392 Giessen, Germany., Wolf SA; Genome Competence Centre, Robert Koch Institute, 13353 Berlin, Germany., Prenger-Berninghoff E; Institute of Hygiene and Infectious Diseases of Animals, Faculty of Veterinary Medicine, Justus Liebig University Giessen, 35392 Giessen, Germany., Thrukonda L; Genome Competence Centre, Robert Koch Institute, 13353 Berlin, Germany., Semmler T; Genome Competence Centre, Robert Koch Institute, 13353 Berlin, Germany., Ewers C; Institute of Hygiene and Infectious Diseases of Animals, Faculty of Veterinary Medicine, Justus Liebig University Giessen, 35392 Giessen, Germany.
المصدر: Antibiotics (Basel, Switzerland) [Antibiotics (Basel)] 2023 Dec 30; Vol. 13 (1). Date of Electronic Publication: 2023 Dec 30.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101637404 Publication Model: Electronic Cited Medium: Print ISSN: 2079-6382 (Print) Linking ISSN: 20796382 NLM ISO Abbreviation: Antibiotics (Basel) Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI AG, 2012-
مستخلص: Extraintestinal pathogenic Escherichia coli (ExPEC) account for over 80% and 60% of bacterial urinary tract infections (UTIs) in humans and animals, respectively. As shared uropathogenic E. coli (UPEC) strains have been previously reported among humans and pets, our study aimed to characterize E. coli lineages among UTI isolates from dogs and cats and to assess their overlaps with human UPEC lineages. We analysed 315 non-duplicate E. coli isolates from the UT of dogs (198) and cats (117) collected in central Germany in 2019 and 2020 utilizing whole genome sequencing and in silico methods. Phylogroup B2 (77.8%), dog-associated sequence type (ST) 372 (18.1%), and human-associated ST73 (16.6%), were predominant. Other STs included ST12 (8.6%), ST141 (5.1%), ST127 (4.8%), and ST131 (3.5%). Among these, 58.4% were assigned to the ExPEC group and 51.1% to the UPEC group based on their virulence associated gene (VAG) profile (ExPEC, presence of ≥VAGs: papAH and/or papC , sfa / focG , afaD / draBC , kpsMT II, and iutA; UPEC , additionally cnf1 or hlyD ). Extended-spectrum cephalosporin (ESC) resistance mediated by extended-spectrum β-lactamases (ESBL) and AmpC-β-lactamase was identified in 1.9% of the isolates, along with one carbapenemase-producing isolate and one isolate carrying a mcr gene. Low occurrence of ESC-resistant or multidrug-resistant (MDR) isolates (2.9%) in the two most frequently detected STs implies that E. coli isolated from UTIs of companion animals are to a lesser extent associated with resistance, but possess virulence-associated genes enabling efficient UT colonization and carriage. Detection of human-related pandemic lineages suggests interspecies transmission and underscores the importance of monitoring companion animals.
References: Bioinformatics. 2018 Jul 15;34(14):2490-2492. (PMID: 29506019)
Microbiol Spectr. 2022 Jun 29;10(3):e0129122. (PMID: 35674442)
Infect Drug Resist. 2020 Jun 17;13:1839-1850. (PMID: 32606833)
J Antimicrob Chemother. 2010 Apr;65(4):651-60. (PMID: 20118165)
J Clin Microbiol. 2018 Aug 27;56(9):. (PMID: 29997200)
Microorganisms. 2020 Jun 05;8(6):. (PMID: 32517147)
Front Microbiol. 2019 Jun 05;10:1260. (PMID: 31231344)
Tierarztl Prax Ausg K Kleintiere Heimtiere. 2014;42(4):231-9. (PMID: 25119631)
Curr Opin Infect Dis. 2009 Dec;22(6):535-43. (PMID: 19797945)
Antibiotics (Basel). 2022 Dec 01;11(12):. (PMID: 36551391)
J Clin Microbiol. 2003 Jan;41(1):337-45. (PMID: 12517870)
FEMS Microbiol Lett. 2007 May;270(2):265-71. (PMID: 17326753)
Antibiotics (Basel). 2020 Oct 20;9(10):. (PMID: 33092201)
Open Forum Infect Dis. 2019 Oct 09;6(11):ofz431. (PMID: 31696141)
mSphere. 2018 Jul 18;3(4):. (PMID: 30021879)
Nat Rev Microbiol. 2015 May;13(5):269-84. (PMID: 25853778)
Antimicrob Agents Chemother. 2006 Feb;50(2):649-53. (PMID: 16436722)
mBio. 2013 Dec 17;4(6):e00377-13. (PMID: 24345742)
Porcine Health Manag. 2016 Sep 1;2:20. (PMID: 28405446)
Antibiotics (Basel). 2020 Apr 04;9(4):. (PMID: 32260467)
Acta Vet Scand. 2017 May 19;59(1):31. (PMID: 28526080)
Microb Genom. 2023 Feb;9(2):. (PMID: 36752777)
J Antimicrob Chemother. 2013 Dec;68(12):2802-8. (PMID: 23833179)
Clin Microbiol Infect. 2012 Jul;18(7):646-55. (PMID: 22519858)
Int J Urol. 2006 Jun;13(6):754-60. (PMID: 16834656)
J Infect Dis. 2001 Mar 1;183 Suppl 1:S1-4. (PMID: 11171002)
Bioinformatics. 2015 Nov 15;31(22):3691-3. (PMID: 26198102)
Front Microbiol. 2017 Dec 01;8:2334. (PMID: 29250044)
J Lab Clin Med. 2002 Mar;139(3):155-62. (PMID: 11944026)
J Glob Antimicrob Resist. 2019 Jun;17:305-308. (PMID: 30682563)
Exp Mol Pathol. 2008 Aug;85(1):11-9. (PMID: 18482721)
J Feline Med Surg. 2022 Aug;24(8):806-814. (PMID: 34709080)
Antimicrob Agents Chemother. 2011 Dec;55(12):5666-75. (PMID: 21947397)
Clin Microbiol Infect. 2006 Sep;12(9):880-6. (PMID: 16882293)
J Clin Microbiol. 2003 Dec;41(12):5798-802. (PMID: 14662987)
Euro Surveill. 2018 Jul;23(27):. (PMID: 29991384)
Microorganisms. 2020 Oct 31;8(11):. (PMID: 33142871)
Infect Immun. 2012 Dec;80(12):4115-22. (PMID: 22966046)
PLoS One. 2015 Nov 20;10(11):e0143335. (PMID: 26587840)
Infect Ecol Epidemiol. 2016 Jun 20;6:31514. (PMID: 27330043)
Microb Genom. 2021 Nov;7(11):. (PMID: 34739369)
Microb Pathog. 2021 Jun;155:104920. (PMID: 33930418)
Front Microbiol. 2020 Sep 02;11:1968. (PMID: 32983008)
Front Cell Infect Microbiol. 2017 Jun 08;7:241. (PMID: 28642845)
Clin Infect Dis. 2019 Jan 7;68(2):334-337. (PMID: 29961843)
Vet Microbiol. 2020 Mar;242:108601. (PMID: 32122604)
Front Microbiol. 2017 Aug 15;8:1566. (PMID: 28861072)
Front Microbiol. 2020 Apr 21;11:580. (PMID: 32373083)
Biochemistry. 2014 Mar 18;53(10):1565-74. (PMID: 24576155)
Antimicrob Agents Chemother. 2006 Jul;50(7):2573-6. (PMID: 16801449)
J Clin Microbiol. 2005 Aug;43(8):3895-900. (PMID: 16081928)
Vet J. 2019 May;247:8-25. (PMID: 30971357)
Bioinformatics. 2019 Nov 1;35(21):4453-4455. (PMID: 31070718)
Vet J. 2011 Oct;190(1):22-7. (PMID: 21239193)
J Infect Dis. 2002 May 15;185(10):1439-47. (PMID: 11992279)
Front Microbiol. 2018 Jun 14;9:1265. (PMID: 29963026)
Nucleic Acids Res. 2021 Jul 2;49(W1):W293-W296. (PMID: 33885785)
Vet Microbiol. 2018 Mar;216:79-84. (PMID: 29519530)
Int J Antimicrob Agents. 2015 Sep;46(3):297-306. (PMID: 26215780)
Microbiol Spectr. 2015 Oct;3(5):. (PMID: 26542041)
Front Microbiol. 2019 Dec 10;10:2852. (PMID: 31921034)
J Feline Med Surg. 2020 Jul;22(7):613-622. (PMID: 31524037)
Clin Microbiol Rev. 2009 Jan;22(1):161-82, Table of Contents. (PMID: 19136439)
Open Forum Infect Dis. 2016 Jun 16;3(3):ofw129. (PMID: 27703993)
Clin Microbiol Rev. 2005 Oct;18(4):657-86. (PMID: 16223952)
Antibiotics (Basel). 2022 Sep 13;11(9):. (PMID: 36140020)
Int J Antimicrob Agents. 2016 Jun;47(6):430-5. (PMID: 27179815)
J Comput Biol. 2012 May;19(5):455-77. (PMID: 22506599)
Int J Med Microbiol. 2005 Oct;295(6-7):383-404. (PMID: 16238015)
J Vet Diagn Invest. 2018 Jan;30(1):64-70. (PMID: 28971754)
Pathogens. 2022 Jun 17;11(6):. (PMID: 35745552)
Appl Environ Microbiol. 2000 Oct;66(10):4555-8. (PMID: 11010916)
J Microbiol Immunol Infect. 2016 Aug;49(4):591-4. (PMID: 26212311)
Appl Environ Microbiol. 2020 Nov 24;86(24):. (PMID: 33036993)
Restor Dent Endod. 2017 May;42(2):152-155. (PMID: 28503482)
EcoSal Plus. 2018 Apr;8(1):. (PMID: 29667573)
mBio. 2020 May 19;11(3):. (PMID: 32430467)
J Antimicrob Chemother. 2018 Feb 1;73(2):377-384. (PMID: 29136156)
Vet Microbiol. 2020 Oct;249:108822. (PMID: 32937249)
Nat Rev Urol. 2010 Dec;7(12):653-60. (PMID: 21139641)
Vet Microbiol. 2013 Mar 23;162(2-4):992-996. (PMID: 23177909)
Environ Microbiol. 2019 Aug;21(8):3107-3117. (PMID: 31188527)
J Antimicrob Chemother. 2019 Oct 1;74(10):3111-3113. (PMID: 31299071)
J Antimicrob Chemother. 2004 Aug;54(2):321-32. (PMID: 15254022)
J Clin Microbiol. 2014 Feb;52(2):407-18. (PMID: 24478469)
J Infect Dis. 1995 Aug;172(2):440-5. (PMID: 7622887)
Microbiology (Reading). 2016 Nov;162(11):1904-1912. (PMID: 27666313)
J Vet Intern Med. 2021 Sep;35(5):2277-2286. (PMID: 34397135)
FEMS Microbiol Ecol. 2016 Jan;92(1):. (PMID: 26656065)
Antibiotics (Basel). 2022 Jan 25;11(2):. (PMID: 35203754)
فهرسة مساهمة: Keywords: ExPEC; ST372; ST73; UPEC; antimicrobial resistance genes; cat; dog; phylogroup B2
تواريخ الأحداث: Date Created: 20240122 Latest Revision: 20240128
رمز التحديث: 20240128
مُعرف محوري في PubMed: PMC10812829
DOI: 10.3390/antibiotics13010038
PMID: 38247597
قاعدة البيانات: MEDLINE
الوصف
تدمد:2079-6382
DOI:10.3390/antibiotics13010038