دورية أكاديمية
Predictive Factors for Critical Weight Loss in Saudi Head and Neck Cancer Patients Undergoing (Chemo)Radiotherapy.
| العنوان: | Predictive Factors for Critical Weight Loss in Saudi Head and Neck Cancer Patients Undergoing (Chemo)Radiotherapy. |
|---|---|
| المؤلفون: | Redwan AS; Clinical Nutrition Department, Faculty of Applied Medical Sciences, Umm Al-Qura University, P.O. Box 715, Makkah 21955, Saudi Arabia.; Clinical Nutrition Administration, King Abdullah Medical City, P.O. Box 24246, Makkah 21955, Saudi Arabia., Kattan FA; Clinical Nutrition Administration, King Abdullah Medical City, P.O. Box 24246, Makkah 21955, Saudi Arabia., Alidrisi MA; Radiation Oncology Department, King Abdullah Medical City, P.O. Box 24246, Makkah 21955, Saudi Arabia., Ali GA; Radiation Oncology Department, King Abdullah Medical City, P.O. Box 24246, Makkah 21955, Saudi Arabia., Ghaith MM; Department of Clinical Laboratory Sciences, Faculty of Applied Medical Sciences, Umm Al-Qura University, P.O. Box 715, Makkah 21955, Saudi Arabia., Arbaeen AF; Department of Clinical Laboratory Sciences, Faculty of Applied Medical Sciences, Umm Al-Qura University, P.O. Box 715, Makkah 21955, Saudi Arabia., Almasmoum HA; Department of Clinical Laboratory Sciences, Faculty of Applied Medical Sciences, Umm Al-Qura University, P.O. Box 715, Makkah 21955, Saudi Arabia., Almohmadi NH; Clinical Nutrition Department, Faculty of Applied Medical Sciences, Umm Al-Qura University, P.O. Box 715, Makkah 21955, Saudi Arabia., Alkholy SO; Clinical Nutrition Department, Faculty of Applied Medical Sciences, Umm Al-Qura University, P.O. Box 715, Makkah 21955, Saudi Arabia., Alhassani WE; Clinical Nutrition Department, Faculty of Applied Medical Sciences, Umm Al-Qura University, P.O. Box 715, Makkah 21955, Saudi Arabia., Abusudah WF; Clinical Nutrition Department, Faculty of Applied Medical Sciences, Umm Al-Qura University, P.O. Box 715, Makkah 21955, Saudi Arabia., Babateen AM; Clinical Nutrition Department, Faculty of Applied Medical Sciences, Umm Al-Qura University, P.O. Box 715, Makkah 21955, Saudi Arabia., Ghabashi MA; Clinical Nutrition Department, Faculty of Applied Medical Sciences, Umm Al-Qura University, P.O. Box 715, Makkah 21955, Saudi Arabia., Obeidat AA; Department of Nutrition and Food Technology, School of Agriculture, The University of Jordan, Amman 11942, Jordan., Al Yacoub AN; Department of Biology, Faculty of Applied Science, Umm Al-Qura University, P.O. Box 715, Makkah 24382, Saudi Arabia., Alazzeh AY; Department of Clinical Nutrition, Faculty of Applied Medical Sciences, University of Ha'il, Ha'il 21955, Saudi Arabia., Azzeh FS; Clinical Nutrition Department, Faculty of Applied Medical Sciences, Umm Al-Qura University, P.O. Box 715, Makkah 21955, Saudi Arabia. |
| المصدر: | Cancers [Cancers (Basel)] 2024 Jan 18; Vol. 16 (2). Date of Electronic Publication: 2024 Jan 18. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: MDPI Country of Publication: Switzerland NLM ID: 101526829 Publication Model: Electronic Cited Medium: Print ISSN: 2072-6694 (Print) Linking ISSN: 20726694 NLM ISO Abbreviation: Cancers (Basel) Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: Basel, Switzerland : MDPI |
| مستخلص: | Weight loss is a significant health problem among patients with head and neck cancer (HNC) that is attributable primarily to the tumor or tumor therapy. Critical weight loss (CWL) is defined as the unintentional loss of ≥5% of weight. Therefore, this study's goal was to investigate and determine the possible factors influencing CWL among patients with HNC who have received radiotherapy or concurrent chemoradiotherapy (CCRT). We conducted a retrospective analysis of 175 patients who received radiotherapy or CCRT as either their primary, adjuvant, or combined treatment at the Oncology Center in King Abdullah Medical City. All patients were ≥18 years of age and diagnosed with HNC with no metastasis. The study results showed that 107 patients (61%) had CWL, while 68 (39%) did not. The following factors were significantly predictive of CWL with a multivariate regression analysis: pretreatment BMI (AOR = 1.1, 95% CI = 1.02-1.17), oral cavity cancer (AOR = 10.36, 95% CI = 1.13-94.55), and male sex (AOR = 3.15, 95% CI = 1.39-7.11). In conclusion, weight loss is highly prevalent among HNC patients during treatment. Accordingly, pretreatment BMI, cancer in the oral cavity, and being male can be considered predictive factors for CWL. |
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| فهرسة مساهمة: | Keywords: Makkah; chemotherapy; critical weight loss; head and neck cancer; radiotherapy |
| تواريخ الأحداث: | Date Created: 20240123 Latest Revision: 20240128 |
| رمز التحديث: | 20240128 |
| مُعرف محوري في PubMed: | PMC10814742 |
| DOI: | 10.3390/cancers16020414 |
| PMID: | 38254902 |
| قاعدة البيانات: | MEDLINE |
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