دورية أكاديمية
YELLOW ALERT: Persistent Yellow Fever Virus Circulation among Non-Human Primates in Urban Areas of Minas Gerais State, Brazil (2021-2023).
العنوان: | YELLOW ALERT: Persistent Yellow Fever Virus Circulation among Non-Human Primates in Urban Areas of Minas Gerais State, Brazil (2021-2023). |
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المؤلفون: | Garcia-Oliveira GF; Laboratório de Vírus, Departament of Microbiology, Universidade Federal de Minas Gerais, Belo Horizonte CEP 31270-901, Brazil., Guimarães ACDS; Laboratório de Vírus, Departament of Microbiology, Universidade Federal de Minas Gerais, Belo Horizonte CEP 31270-901, Brazil., Moreira GD; Laboratório de Vírus, Departament of Microbiology, Universidade Federal de Minas Gerais, Belo Horizonte CEP 31270-901, Brazil., Costa TA; Laboratório de Vírus, Departament of Microbiology, Universidade Federal de Minas Gerais, Belo Horizonte CEP 31270-901, Brazil., Arruda MS; Laboratório de Vírus, Departament of Microbiology, Universidade Federal de Minas Gerais, Belo Horizonte CEP 31270-901, Brazil., de Mello ÉM; Centro de Controle de Zoonoses, Prefeitura de Belo Horizonte, Belo Horizonte CEP 31270-705, Minas Gerais, Brazil., Silva MC; Laboratório de Zoonoses, Prefeitura de Belo Horizonte, Belo Horizonte CEP 31270-705, Minas Gerais, Brazil., de Almeida MG; Laboratório de Zoonoses, Prefeitura de Belo Horizonte, Belo Horizonte CEP 31270-705, Minas Gerais, Brazil., Hanley KA; Department of Biology, New Mexico State University, Las Cruces, NM 88003-8801, USA., Vasilakis N; Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555-0609, USA.; Center for Vector-Borne and Zoonotic Diseases, The University of Texas Medical Branch, Galveston, TX 77555-0609, USA.; Institute for Human Infection and Immunity, University of Texas Medical Branch, Galveston, TX 77555-0610, USA., Drumond BP; Laboratório de Vírus, Departament of Microbiology, Universidade Federal de Minas Gerais, Belo Horizonte CEP 31270-901, Brazil. |
المصدر: | Viruses [Viruses] 2023 Dec 23; Vol. 16 (1). Date of Electronic Publication: 2023 Dec 23. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915 (Electronic) Linking ISSN: 19994915 NLM ISO Abbreviation: Viruses Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: Basel, Switzerland : MDPI |
مواضيع طبية MeSH: | Yellow fever virus*/genetics , Yellow Fever*/epidemiology , Yellow Fever*/veterinary, Animals ; Brazil/epidemiology ; 5' Untranslated Regions ; Callithrix |
مستخلص: | Yellow fever virus (YFV) is the agent of yellow fever (YF), which affects both humans and non-human primates (NHP). Neotropical NHP are highly susceptible to YFV and considered sentinels for YFV circulation. Brazil faced a significant YF outbreak in 2017-2018, with over 2000 human cases and 2000 epizootics cases, mainly in the State of Minas Gerais, Brazil. This study aimed to investigate whether YFV circulation persisted in NHP after the human outbreak had subsided. To this end, NHP carcass samples collected in Minas Gerais from 2021 to 2023 were screened for YFV. RNA was extracted from tissue fragments and used in RT-qPCR targeting the YFV 5'UTR. Liver and lung samples from 166 animals were tested, and the detection of the β-actin mRNA was used to ensure adequacy of RNA isolation. YFV RNA was detected in the liver of 18 NHP carcasses collected mainly from urban areas in 2021 and 2022. YFV positive NHP were mostly represented by Callithrix, from 5 out of the 12 grouped municipalities (mesoregions) in Minas Gerais state. These findings reveal the continued YFV circulation in NHP in urban areas of Minas Gerais during 2021 and 2022, with the attendant risk of re-establishing the urban YFV cycle. |
References: | PLoS Negl Trop Dis. 2018 Jun 4;12(6):e0006538. (PMID: 29864115) Emerg Infect Dis. 2021 Jan;27(1):47-56. (PMID: 33350931) Emerg Top Life Sci. 2020 Dec 11;4(4):399-410. (PMID: 33258924) Rev Saude Publica. 2010 Dec;44(6):1144-9. (PMID: 21109907) Virol J. 2013 Feb 14;10:58. (PMID: 23410000) PLoS Negl Trop Dis. 2020 Oct 5;14(10):e0008658. (PMID: 33017419) Virol J. 2020 Jan 23;17(1):9. (PMID: 31973727) Vaccines (Basel). 2019 Dec 04;7(4):. (PMID: 31817103) Viruses. 2023 Mar 15;15(3):. (PMID: 36992466) J Clin Virol. 2015 Mar;64:160-73. (PMID: 25453327) Viruses. 2021 Oct 01;13(10):. (PMID: 34696408) Mem Inst Oswaldo Cruz. 2022 Dec 02;117:e220127. (PMID: 36478156) J Clin Microbiol. 2012 Dec;50(12):4054-60. (PMID: 23052311) PLoS Negl Trop Dis. 2023 Jun 5;17(6):e0011407. (PMID: 37276217) Sci Justice. 2004 Jan-Mar;44(1):35-41. (PMID: 14964820) Sci Rep. 2021 Aug 11;11(1):16277. (PMID: 34381111) Trends Microbiol. 2018 Nov;26(11):913-928. (PMID: 29933925) Viruses. 2023 Feb 04;15(2):. (PMID: 36851651) Parasit Vectors. 2020 Feb 19;13(1):90. (PMID: 32075684) |
معلومات مُعتمدة: | U01 AI151807 United States AI NIAID NIH HHS |
فهرسة مساهمة: | Keywords: Brazil; Orthoflavivirus; epizootics; non-human primate; outbreaks; surveillance; yellow fever; yellow fever virus |
المشرفين على المادة: | 0 (5' Untranslated Regions) |
تواريخ الأحداث: | Date Created: 20240123 Date Completed: 20240124 Latest Revision: 20240523 |
رمز التحديث: | 20240523 |
مُعرف محوري في PubMed: | PMC10818614 |
DOI: | 10.3390/v16010031 |
PMID: | 38257732 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1999-4915 |
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DOI: | 10.3390/v16010031 |