دورية أكاديمية
أعرض في EDS

Potentially inappropriate prescriptions and potential prescription omissions in older people living with HIV.

التفاصيل البيبلوغرافية
العنوان: Potentially inappropriate prescriptions and potential prescription omissions in older people living with HIV.
المؤلفون: Fernández-Fradejas J; Pharmacy Department, University Hospital Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain., Delgado-Silveira E; Pharmacy Department, University Hospital Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain., González-Burgos E; Department of Pharmacology, Pharmacognosy and Botany, Faculty of Pharmacy, Complutense University of Madrid, Madrid, Spain., Álvarez-Díaz AM; Pharmacy Department, University Hospital Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain., Vélez-Díaz-Pallarés M; Pharmacy Department, University Hospital Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain.
المصدر: HIV medicine [HIV Med] 2024 May; Vol. 25 (5), pp. 587-599. Date of Electronic Publication: 2024 Jan 23.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Multicenter Study
اللغة: English
بيانات الدورية: Publisher: Wiley Country of Publication: England NLM ID: 100897392 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-1293 (Electronic) Linking ISSN: 14642662 NLM ISO Abbreviation: HIV Med Subsets: MEDLINE
أسماء مطبوعة: Publication: Oxford : Wiley
Original Publication: Oxford : Blackwell Science, c1999-
مواضيع طبية MeSH: Inappropriate Prescribing*/statistics & numerical data , HIV Infections*/drug therapy , HIV Infections*/epidemiology, Humans ; Male ; Female ; Aged ; Retrospective Studies ; Cross-Sectional Studies ; Spain/epidemiology ; Aged, 80 and over ; Risk Factors ; Potentially Inappropriate Medication List ; Prevalence ; Drug Prescriptions/statistics & numerical data
مستخلص: Objectives: This study aimed to determine the prevalence of potentially inappropriate prescriptions (PIPs) and potential prescription omissions (PPOs) in a Spanish cohort of people living with HIV (PLWH) aged ≥65 years and to identify risk factors for the presence of PIPs and PPOs.
Methods: This retrospective cross-sectional study was conducted across 10 public hospitals in the Autonomous Community of Madrid, Spain. Clinical and demographic data were cross-checked against hospital and community pharmacy dispensation registries. PIPs and PPOs were assessed using the American Geriatrics Society (AGS)/Beers and Screening Tool of Older Persons' Prescriptions (STOPP)/Screening Tool to Alert Doctors to Right Treatment (START) criteria. Risk factors for PIPs and PPOs and agreement between AGS/Beers and STOPP/START criteria were statistically analysed.
Results: This study included 313 PLWH (median age 72 years), of whom 80.5% were men. PIP prevalence rates were 29.4% and 44.4% based on the AGS/Beers and STOPP criteria, respectively. The concordance between AGS/Beers and STOPP criteria was moderate. Benzodiazepines and proton pump inhibitors were the chronic comedications most commonly involved in PIPs. PPOs were observed in 61.4% of the patients. The leading omissions were insufficient influenza and pneumococcal vaccine coverage and inadequate bone health-related treatments. The number of chronic comedications, female sex, neuropsychiatric disorders, and cancer diagnosis were risk factors for PIPs, whereas osteopenia and osteoporosis were risk factors for PPOs.
Conclusions: A high prevalence of PIPs and PPOs was observed in our cohort of older PLWH. These findings emphasize the importance of comprehensive medication reviews in this population to reduce inappropriate medication use and address their specific and underserved therapeutic needs.
(© 2024 British HIV Association.)
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فهرسة مساهمة: Keywords: HIV; aged; inappropriate prescribing; polypharmacy
تواريخ الأحداث: Date Created: 20240123 Date Completed: 20240508 Latest Revision: 20240607
رمز التحديث: 20240607
DOI: 10.1111/hiv.13616
PMID: 38258538
قاعدة البيانات: MEDLINE
الوصف
تدمد:1468-1293
DOI:10.1111/hiv.13616