دورية أكاديمية
Case of persistent corneal epithelial damage after cataract surgery leading to diagnosis of vitamin A deficiency.
| العنوان: | Case of persistent corneal epithelial damage after cataract surgery leading to diagnosis of vitamin A deficiency. |
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| المؤلفون: | Yamada F; Department of Ophthalmology, Mie University School of Medicine, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan., Kato K; Department of Ophthalmology, Mie University School of Medicine, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan. k-kato@clin.medic.mie-u.ac.jp., Nagashima R; Department of Ophthalmology, Mie University School of Medicine, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan., Yonekawa Y; Department of Ophthalmology, Mie University School of Medicine, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan., Kashima Y; Department of Ophthalmology, Mie University School of Medicine, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan., Kondo M; Department of Ophthalmology, Mie University School of Medicine, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan. |
| المصدر: | Documenta ophthalmologica. Advances in ophthalmology [Doc Ophthalmol] 2024 Apr; Vol. 148 (2), pp. 121-128. Date of Electronic Publication: 2024 Jan 24. |
| نوع المنشور: | Case Reports; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Kluwer Country of Publication: Netherlands NLM ID: 0370667 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-2622 (Electronic) Linking ISSN: 00124486 NLM ISO Abbreviation: Doc Ophthalmol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Dordrecht : Kluwer Original Publication: s'-Gravenhage [etc.] |
| مواضيع طبية MeSH: | Vitamin A Deficiency*/diagnosis , Vitamin A Deficiency*/etiology , Vision, Low* , Cataract*, Male ; Humans ; Aged ; Electroretinography/methods ; Vitamin A ; Vision Disorders/diagnosis ; Vision Disorders/etiology ; Tomography, Optical Coherence/methods |
| مستخلص: | Purpose: To report our findings of reduced full-field electroretinograms (ff-ERGs) and abnormal optical coherence tomographic (OCT) images in a patient with poor visual acuity after cataract surgery who was eventually diagnosed with vitamin A deficiency (VAD). Methods: This was a clinical study of a patient who complained of blurred vision after cataract surgery. To determine the cause of the reduced vision, we recorded full-field electroretinograms (ff-ERGs) to determine the scotopic and photopic status of the retina. We also performed optical coherence tomography to assess the changes in the retinal structure. Serological tests were performed. Results: A 74-year-old man presented with persistent corneal epithelial damages and reduced vision that developed after conventional cataract surgery. OCT showed an interrupted ellipsoid zone, and fundus autofluorescence (FAF) showed a severe hypofluorescence in the retina of the left eye. The scotopic ff-ERGs were severely reduced, and the photopic ff-ERGs were mildly reduced. Serological examinations revealed a vitamin A concentration < 7 IU/dL (normal, 97-316 IU/dL). Based on these findings, we diagnosed the patient with VAD and started treatment with oral vitamin A supplements. After three months, his visual acuity, ff-ERGs, and OCT findings recovered to normal levels. The amplitudes and implicit times of the RETeval flicker ERGs increased to be within the normal range, and the hypofluorescence of the left eye disappeared. The length of the photoreceptor outer segments increased after the vitamin A supplementation. Conclusion: Our findings indicate that the ERGs are helpful for diagnosing patients with VAD associated with persistent corneal epithelial damages. (© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.) |
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| فهرسة مساهمة: | Keywords: Flicker ERG; Fundus autofluorescence; Optical coherence tomography; Photoreceptor outer segment length; RETeval; Vitamin A deficiency |
| المشرفين على المادة: | 11103-57-4 (Vitamin A) |
| تواريخ الأحداث: | Date Created: 20240124 Date Completed: 20240322 Latest Revision: 20240322 |
| رمز التحديث: | 20240322 |
| DOI: | 10.1007/s10633-023-09963-6 |
| PMID: | 38265517 |
| قاعدة البيانات: | MEDLINE |
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