دورية أكاديمية
أعرض في EDS

Oxygen saturation thresholds in managing sickle cell disease at US children's hospitals.

التفاصيل البيبلوغرافية
العنوان: Oxygen saturation thresholds in managing sickle cell disease at US children's hospitals.
المؤلفون: Yadav A; Department of Pediatrics, McGovern Medical School at the University of Texas Health Science Center at Houston (UTHealth Houston) and Children's Memorial Hermann Hospital, Houston, Texas, USA., Munir F; Department of Pediatrics, Pediatric Hematology Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Chan KH; Division of Hematology/Oncology, Department of Internal Medicine, McGovern Medical School at the University of Texas Health Science Center at Houston (UTHealth Houston), Houston, Texas, USA., Quraishi MZ; Department of Pediatrics, McGovern Medical School at the University of Texas Health Science Center at Houston (UTHealth Houston) and Children's Memorial Hermann Hospital, Houston, Texas, USA., Harris TS; Department of Pediatrics, McGovern Medical School at the University of Texas Health Science Center at Houston (UTHealth Houston) and Children's Memorial Hermann Hospital, Houston, Texas, USA., Brown DL; Department of Pediatrics, McGovern Medical School at the University of Texas Health Science Center at Houston (UTHealth Houston) and Children's Memorial Hermann Hospital, Houston, Texas, USA., Menon N; Department of Pediatrics, McGovern Medical School at the University of Texas Health Science Center at Houston (UTHealth Houston) and Children's Memorial Hermann Hospital, Houston, Texas, USA., Nguyen TT; Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA., Srivaths L; Department of Pediatrics, McGovern Medical School at the University of Texas Health Science Center at Houston (UTHealth Houston) and Children's Memorial Hermann Hospital, Houston, Texas, USA.
المصدر: Pediatric blood & cancer [Pediatr Blood Cancer] 2024 Apr; Vol. 71 (4), pp. e30879. Date of Electronic Publication: 2024 Jan 27.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: John Wiley Country of Publication: United States NLM ID: 101186624 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-5017 (Electronic) Linking ISSN: 15455009 NLM ISO Abbreviation: Pediatr Blood Cancer Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Hoboken, N.J. : John Wiley, c 2004-
مواضيع طبية MeSH: Volatile Organic Compounds* , Anemia, Sickle Cell*/therapy , Anemia, Sickle Cell*/complications , Acute Chest Syndrome*/etiology , Acute Chest Syndrome*/therapy, Child ; Humans ; United States ; Oxygen Saturation ; Oxygen ; Hospitals
مستخلص: Background: Adequate oxygen saturation (SpO 2 ) is crucial for managing sickle cell disease (SCD). Children with SCD are at increased risk for occult hypoxemia; therefore, understanding SpO 2 threshold practices would help identify barriers to oxygen optimization in a population sensitive to oxyhemoglobin imbalances. We investigated SpO 2 cutoff levels used in clinical algorithms for management of acute SCD events at children's hospitals across the United States, and determined their consistency with recommended national guidelines (SpO 2  > 95%).
Methods: Clinical pathways and algorithms used for the management of vaso-occlusive crisis (VOC) and acute chest syndrome (ACS) in SCD were obtained and reviewed from large children's hospitals in the United States.
Results: Responses were obtained from 94% (140/149) of eligible children's hospitals. Of these, 63 (45%) had available clinical algorithms to manage VOC and ACS. SpO 2 cutoff was provided in 71.4% (45/63) of clinical algorithms. Substantial variation in SpO 2 cutoff levels was noted, ranging from ≥90% to more than 95%. Only seven hospitals (5% of total hospitals and 15.6% of hospitals with clinical algorithms available) specified oxygen cutoffs that were consistent with national guidelines. Hospitals geographically located in the South (46.8%; n = 29/62) and Midwest (54.8%; n = 17/31) were more likely to have VOC and ACS clinical algorithms, compared to the Northeast (26.5%; n = 9/34) and West (36.4%; n = 8/22).
Conclusion: There is inconsistency in the use of clinical algorithms and oxygen thresholds for VOC and ACS across US children's hospitals. Children with SCD could be at risk for insufficient oxygen therapy during adverse acute events.
(© 2024 Wiley Periodicals LLC.)
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فهرسة مساهمة: Keywords: clinical algorithm; clinical pathway; disparity; hypoxemia; oxygen; pulse oximetry; sickle cell disease
المشرفين على المادة: 0 (Volatile Organic Compounds)
S88TT14065 (Oxygen)
تواريخ الأحداث: Date Created: 20240127 Date Completed: 20240226 Latest Revision: 20240226
رمز التحديث: 20240226
DOI: 10.1002/pbc.30879
PMID: 38279845
قاعدة البيانات: MEDLINE
الوصف
تدمد:1545-5017
DOI:10.1002/pbc.30879