دورية أكاديمية

Determination of aflatoxin M 1 and ochratoxin A in breast milk in rural centers of Yazd, Iran: Exposure assessment and risk characterization.

التفاصيل البيبلوغرافية
العنوان: Determination of aflatoxin M 1 and ochratoxin A in breast milk in rural centers of Yazd, Iran: Exposure assessment and risk characterization.
المؤلفون: Rezaei Z; Center of Cheshme noshan khorasan (Alis), University of Applied Science and Technology, Chanaran, Iran., Hamzeh Pour S; Department of Pathobiology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran., Ezati P; BioNanocomposite Research Center, Department of Food and Nutrition, Kyung Hee University, 26 Kyungheedae‑Ro, Dongdaemun‑Gu, Seoul, 02447, Republic of Korea., Akrami-Mohajeri F; Infectious Diseases Research Center, Shahid Sadoughi Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Fateme.akrami@gmail.com.; Department of Food Hygiene and Safety, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Fateme.akrami@gmail.com.
المصدر: Mycotoxin research [Mycotoxin Res] 2024 May; Vol. 40 (2), pp. 211-221. Date of Electronic Publication: 2024 Jan 29.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Springer-Verlag Berlin Country of Publication: Germany NLM ID: 8807334 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1867-1632 (Electronic) Linking ISSN: 01787888 NLM ISO Abbreviation: Mycotoxin Res Subsets: MEDLINE
أسماء مطبوعة: Publication: Heidelberg : Springer-Verlag Berlin
Original Publication: Mainz, Federal Republic of Germany : Hans W. Schmidt, 1985-
مواضيع طبية MeSH: Aflatoxin M1*/analysis , Ochratoxins*/analysis , Rural Population* , Milk, Human*/chemistry, Humans ; Iran ; Female ; Adult ; Risk Assessment ; Young Adult ; Food Contamination/analysis ; Infant ; Enzyme-Linked Immunosorbent Assay
مستخلص: Breast milk (BM) is considered as the best source of nutrition which could have prevention effects on various diseases in the first years of a child. Along with nutritive compounds, presence of contaminants such as mycotoxins in BM could be transmitted into neonate. The aim of this study was to determine the occurrence, levels, and factors associated with the presence of aflatoxin M 1 (AFM 1 ) and ocratoxin a (OTA) in BM samples of nursing mothers in rural centers of Yazd, Iran. The presence and average AFM 1 and OTA concentration in 72 BM samples was measured by competitive ELISA. The demographic and diet parameters of nursing mothers were collected by a questionnaire and were analyzed using SPSS 18 software. AFM 1 and OTA were detected in 63 (87.5%) and 47 (65.2%) samples with the mean concentration levels of 19.46 ± 13.26 ng/L (ranges from 5.1 to 53.9) and 200 ± 160 ng/L (ranges from 100 to 2460), respectively. Of these, 32 samples (50.7%) for AFM 1 and 23 samples (48.9%) for OTA had values exceeding the limit set by the European Union regulation for infant foods (25 ng/L for AFM 1 and 500 ng/L for OTA). It was also found that the risk of AFM 1 and OTA occurrence in BM increased significantly with the consumption of beans, bread, cereals, fruit juice and crackers, and cream, respectively. This study showed that the estimated daily intake for AFM 1 and OTA by 1 month of age infants was 2.7 and 28.5 ng/kg bw/day, respectively, while, as the age of the infant increased, the values were lower and close to 0.9 and 9.9 ng/kg bw/day for AFM1 and OTA in 12 months of age infants, respectively. The high occurrence and noticeable levels of AFM 1 and OTA detected in this study indicated that some infants receive undesirable exposures to AFM 1 and OTA with breast milk. Therefore, it is recommended that mothers are advised to avoid certain foods during pregnancy and breastfeeding that are likely sources of mycotoxins.
(© 2024. The Author(s) under exclusive licence to Society for Mycotoxin (Research Gesellschaft für Mykotoxinforschung e.V.) and Springer-Verlag GmbH Germany, part of Springer Nature.)
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معلومات مُعتمدة: 3419 Shahid Sadoughi University of Medical Sciences
فهرسة مساهمة: Keywords: Aflatoxin M1; Breast milk; Mycotoxins; Ocratoxin A
المشرفين على المادة: 6795-23-9 (Aflatoxin M1)
0 (Ochratoxins)
1779SX6LUY (ochratoxin A)
تواريخ الأحداث: Date Created: 20240129 Date Completed: 20240424 Latest Revision: 20240425
رمز التحديث: 20240425
DOI: 10.1007/s12550-024-00519-4
PMID: 38285127
قاعدة البيانات: MEDLINE
الوصف
تدمد:1867-1632
DOI:10.1007/s12550-024-00519-4