دورية أكاديمية
Galectin-9 is a target for the treatment of cancer: A patent review.
| العنوان: | Galectin-9 is a target for the treatment of cancer: A patent review. |
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| المؤلفون: | Rodrigues CF; RENORBIO, Federal University of Ceara, Fortaleza, Brazil., Santos FA; Department of Biochemistry and Molecular Biology, Federal University of Ceara, Fortaleza, Brazil., Amorim LAA; Department of Biochemistry and Molecular Biology, Federal University of Ceara, Fortaleza, Brazil., da Silva ALC; Department of Biochemistry and Molecular Biology, Federal University of Ceara, Fortaleza, Brazil; Post Graduate Program in Biotechnology of Natural Resources, Federal University of Ceara, Fortaleza, Brazil., Marques LGA; Post Graduate Program in Biotechnology of Natural Resources, Federal University of Ceara, Fortaleza, Brazil., Rocha BAM; RENORBIO, Federal University of Ceara, Fortaleza, Brazil; Department of Biochemistry and Molecular Biology, Federal University of Ceara, Fortaleza, Brazil; Post Graduate Program in Biotechnology of Natural Resources, Federal University of Ceara, Fortaleza, Brazil. Electronic address: bruno.rocha@ufc.br. |
| المصدر: | International journal of biological macromolecules [Int J Biol Macromol] 2024 Jan; Vol. 254 (Pt 1), pp. 127768. Date of Electronic Publication: 2023 Oct 30. |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Amsterdam : Elsevier Original Publication: Guildford, Eng., IPC Science and Technology Press. |
| مواضيع طبية MeSH: | Galectins*/metabolism , Neoplasms*/diagnosis , Neoplasms*/drug therapy, Humans ; Carbohydrates |
| مستخلص: | Galectins, which correspond to a group of proteins capable of recognizing and reversibly binding to β-galactoside carbohydrates, have been the subject of innovation and development of technological products. Galectins play biological roles, such as cell proliferation and apoptosis, and some studies showed differences in the concentrations of galectins dispersed in serum of patients with cancer. For this reason, different studies have evaluated the biotechnological potential of these proteins as biomarkers for the prognosis and/or diagnosis of physiological disorders. Thus, this review discusses recent technological advancements in targeting galectins for the treatment of cancer and using galectins for cancer prognosis and diagnosis. Data mining was performed using the search descriptors "Galectin 9* and cancer*" and the ESPACENET and Cortellis Drug Discovery Intelligence (CDDI) databases. PRISMA guidelines were followed as a basis for literature review which aimed to conduct a systematic study of galectin-9 patents related to cancer prognosis, diagnosis and treatment. Results showed the importance of galectin-9 protein patents in furthering biomedical advancements in the global fight against cancer. Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (Copyright © 2023 Elsevier B.V. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Diagnosis; Inhibitors; Lectins; Oncology; cancer treatment |
| المشرفين على المادة: | 0 (Galectins) 0 (Carbohydrates) |
| تواريخ الأحداث: | Date Created: 20240130 Date Completed: 20240131 Latest Revision: 20240131 |
| رمز التحديث: | 20240131 |
| DOI: | 10.1016/j.ijbiomac.2023.127768 |
| PMID: | 38287577 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1879-0003 |
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| DOI: | 10.1016/j.ijbiomac.2023.127768 |