دورية أكاديمية
Considerations for Gender-Affirming Hormonal and Surgical Care Among Transgender and Gender Diverse Adolescents and Adults With Congenital Heart Disease.
| العنوان: | Considerations for Gender-Affirming Hormonal and Surgical Care Among Transgender and Gender Diverse Adolescents and Adults With Congenital Heart Disease. |
|---|---|
| المؤلفون: | Harrison DJ; Colorado Adult and Teen Congenital Heart (C.A.T.C.H.) Program University of Colorado School of Medicine, UCHealth Hospital System and Children's Hospital Colorado Aurora CO USA., Prada F; Division of Adolescent Medicine Children's Hospital Colorado Aurora CO USA., Nokoff NJ; Division of Endocrinology Children's Hospital Colorado Aurora CO USA., Iwamoto SJ; UCHealth Integrated Transgender Program, Division of Endocrinology, Metabolism and Diabetes University of Colorado School of Medicine, Rocky Mountain Regional VA Medical Center Aurora CO USA., Pastor T; Division of Cardiology, Yale New Haven Hospital New Haven CT USA., Jacobsen RM; Colorado Adult and Teen Congenital Heart (C.A.T.C.H.) Program University of Colorado School of Medicine, UCHealth Hospital System and Children's Hospital Colorado Aurora CO USA., Yeung E; Colorado Adult and Teen Congenital Heart (C.A.T.C.H.) Program University of Colorado School of Medicine, UCHealth Hospital System and Children's Hospital Colorado Aurora CO USA. |
| المصدر: | Journal of the American Heart Association [J Am Heart Assoc] 2024 Feb 06; Vol. 13 (3), pp. e031004. Date of Electronic Publication: 2024 Jan 31. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101580524 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2047-9980 (Electronic) Linking ISSN: 20479980 NLM ISO Abbreviation: J Am Heart Assoc Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Oxford : Wiley-Blackwell |
| مواضيع طبية MeSH: | Transgender Persons* , Heart Defects, Congenital*/surgery , Cardiology*, Humans ; Adolescent ; Adult ; Female ; Male ; Child ; Retrospective Studies ; Gender Identity |
| مستخلص: | Background: Transgender and gender diverse (TGD) individuals and long-term survivors with adult congenital heart disease (ACHD) are both growing populations with specialized needs. No studies assess temporal trends or evaluate the care of TGD individuals with ACHD. Methods and Results: Meetings between congenital cardiology and gender-affirming care specialists identified unique considerations in TGD individuals with ACHD. A retrospective chart review was then performed to describe patient factors and outpatient trends in those with an ACHD diagnosis undergoing gender-affirming hormonal or surgical care (GAHT/S) at 1 adult and 1 pediatric tertiary care center. Thirty-three TGD individuals with ACHD were identified, 21 with a history of GAHT/S. Fourteen (66%) had moderate or complex ACHD, 8 (38%) identified as transgender male, 9 (43%) transgender female, and 4 (19%) other gender identities. Three had undergone gender-affirming surgery. There were zero occurrences of the composite end point of unplanned hospitalization or thrombotic event over 71.1 person-years of gender-affirming care. Median age at first gender-affirming appointment was 16.8 years [interquartile range 14.8-21.5]. The most common treatment modification was changing estradiol administration from oral to transdermal to reduce thrombotic risk (n=3). An increasing trend was observed from zero TGD patients with ACHD attending a gender diversity appointment in 2012 to 14 patients in 2022. Conclusions: There is a growing population of TGD patients with ACHD and unique medical and psychosocial needs. Future studies must fully evaluate the reassuring safety profile observed in this small cohort. We share 10 actionable care considerations for providers with a goal of overseeing a safe and fulfilling gender transition across all TGD patients with ACHD. |
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| فهرسة مساهمة: | Keywords: ACHD; congenital heart disease; gender‐affirming care; transgender |
| تواريخ الأحداث: | Date Created: 20240131 Date Completed: 20240207 Latest Revision: 20240430 |
| رمز التحديث: | 20240430 |
| مُعرف محوري في PubMed: | PMC11056179 |
| DOI: | 10.1161/JAHA.123.031004 |
| PMID: | 38293963 |
| قاعدة البيانات: | MEDLINE |
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