دورية أكاديمية
Ambulatory Extracorporeal Membrane Oxygenation Use in Patients Listed for Lung Transplant.
| العنوان: | Ambulatory Extracorporeal Membrane Oxygenation Use in Patients Listed for Lung Transplant. |
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| المؤلفون: | Trivedi JR; From the Department of Cardiothoracic Surgery, University of Louisville, Louisville, Kentucky., Endo T, Sharma A, Fox MP, Slaughter MS, van Berkel VH |
| المصدر: | ASAIO journal (American Society for Artificial Internal Organs : 1992) [ASAIO J] 2024 Jul 01; Vol. 70 (7), pp. 625-632. Date of Electronic Publication: 2024 Feb 01. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9204109 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-943X (Electronic) Linking ISSN: 10582916 NLM ISO Abbreviation: ASAIO J Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Hagerstown, MD : Lippincott Williams & Wilkins Original Publication: Philadelphia, PA : Published for the Society by J.B. Lippincott Co., c1992- |
| مواضيع طبية MeSH: | Extracorporeal Membrane Oxygenation*/methods , Extracorporeal Membrane Oxygenation*/statistics & numerical data , Lung Transplantation*/methods , Lung Transplantation*/statistics & numerical data , Waiting Lists*/mortality, Humans ; Male ; Female ; Middle Aged ; Adult ; Retrospective Studies ; Ambulatory Care/statistics & numerical data ; Ambulatory Care/methods |
| مستخلص: | There has been an increase in the use of extracorporeal membrane oxygenation (ECMO) to bridge critically ill patients to lung transplant (LTX). This study evaluates how ambulatory status on ECMO affected waitlist and post-LTX outcomes. The United Network of Organ Sharing (UNOS) database was queried for patients aged of greater than or equal to 18 years and between 2016 and 2021 to identify pre-LTX patients supported by ECMO. The patients were classified in venous-arterial (VA) ECMO and veno-venous (VV) ECMO cohorts and further classified as ambulatory (AMB) and non-AMB (nAMB). Each cohort was controlled against the non-ECMO patients. Univariate statistical tests, as well as Kaplan-Meier survival curves, were used for analysis. The 90 day waitlist survival was the highest among the non-ECMO group (96%), but both AMB VV and VA groups had superior survival compared to the nAMB group (85% vs. 75%, 78% vs. 65%, p < 0.01). After adjusting for the median lung allocation score (LAS) (88) in the VV ECMO group, the waitlist survival was superior in the AMB VV ECMO compared to those not on ECMO (86% vs. 78%, p > 0.01). The 1 year post-LTX survival between non-ECMO and AMB VV ECMO was comparable (88% vs. 88%, p = 0.66). Ambulating patients or use of physical therapy while on ECMO can help improve lung transplant outcomes. Competing Interests: Disclosure: The authors have no conflicts of interest to report. (Copyright © ASAIO 2024.) |
| References: | Valapour M, Lehr CJ, Schladt DP, et al.: OPTN/SRTR 2021 Annual Data Report: Lung. Am J Transplant. 23: S379–S442, 2023. Egan TM, Murray S, Bustami RT, et al.: Development of the new lung allocation system in the United States. Am J Transplant. 6: 1212–1227, 2006. Russo MJ, Worku B, Iribarne A, et al.: Does lung allocation score maximize survival benefit from lung transplantation? J Thorac Cardiovasc Surg. 141: 1270–1277, 2011. Hayanga JWA, Hayanga HK, Holmes SD, et al.: Mechanical ventilation and extracorporeal membrane oxygenation as a bridge to lung transplantation: Closing the gap. J Heart Lung Transplant. 38: 1104–1111, 2019. Hayes K, Hodgson CL, Webb MJ, Romero L, Holland AE: Rehabilitation of adult patients on extracorporeal membrane oxygenation: A scoping review. Aust Crit Care. 35: 575–582, 2022. Peek GJ, Mugford M, Tiruvoipati R, et al.: Efficacy and economic assessment of conventional ventilatory support versus extracorporeal membrane oxygenation for severe adult respiratory failure (CESAR): A multicentre randomised controlled trial. Lancet. 374: 1351–1363, 9698. Mattar A, Chatterjee S, Loor G: Bridging to lung transplantation. Crit Care Clin. 35: 11–25, 2019. Chiumello D, Coppola S, Froio S, Colombo A, Del Sorbo L: Extracorporeal life support as bridge to lung transplantation: A systematic review. Crit Care. 19: 19, 2015. Hoopes CW, Kukreja J, Golden J, Davenport DL, Diaz-Guzman E, Zwischenberger JB: Extracorporeal membrane oxygenation as a bridge to pulmonary transplantation. J Thorac Cardiovasc Surg. 145: 862–867, 2013. Keller SP: Contemporary approaches in the use of extracorporeal membrane oxygenation to support patients waiting for lung transplantation. Ann Cardiothorac Surg. 9: 29–41, 2020. Nasir BS, Klapper J, Hartwig M: Lung transplant from ECMO: Current results and predictors of post-transplant mortality. Curr Transplant Rep. 8: 140–150, 2021. Kourek C, Nanas S, Kotanidou A, et al.: Modalities of exercise training in patients with extracorporeal membrane oxygenation support. J Cardiovasc Dev Dis. 9: 34, 2022. Ko Y, Cho YH, Park YH, et al.: Feasibility and safety of early physical therapy and active mobilization for patients on extracorporeal membrane oxygenation. ASAIO J. 61: 564–568, 2015. Wells CL, Forrester J, Vogel J, Rector R, Tabatabai A, Herr D: Safety and feasibility of early physical therapy for patients on extracorporeal membrane oxygenator: University of Maryland Medical Center Experience. Crit Care Med. 46: 53–59, 2018. Ferreira DDC, Marcolino MAZ, Macagnan FE, Plentz RDM, Kessler A: Safety and potential benefits of physical therapy in adult patients on extracorporeal membrane oxygenation support: A systematic review. Rev Bras Ter Intensiva. 31: 227–239, 2019. Schweickert WD, Pohlman MC, Pohlman AS, et al.: Early physical and occupational therapy in mechanically ventilated, critically ill patients: A randomised controlled trial. Lancet. 373: 1874–1882, 9678. Keshavamurthy S, Bazan V, Tribble TA, Baz MA, Zwischenberger JB: Ambulatory extracorporeal membrane oxygenation (ECMO) as a bridge to lung transplantation. Indian J Thorac Cardiovasc Surg. 37: 366–379, 2021. Turner DA, Cheifetz IM, Rehder KJ, et al.: Active rehabilitation and physical therapy during extracorporeal membrane oxygenation while awaiting lung transplantation: A practical approach. Crit Care Med. 39: 2593–2598, 2011. Lehr CJ, Zaas DW, Cheifetz IM, Turner DA: Ambulatory extracorporeal membrane oxygenation as a bridge to lung transplantation: Walking while waiting. Chest. 147: 1213–1218, 2015. Hashem MD, Nelliot A, Needham DM: Early mobilization and rehabilitation in the ICU: Moving back to the future. Respir Care. 61: 971–979, 2016. Hodgson C, Bellomo R, Berney S, et al.; TEAM Study Investigators: Early mobilization and recovery in mechanically ventilated patients in the ICU: A bi-national, multi-centre, prospective cohort study. Crit Care. 19: 81, 2015. Stiller K: Physiotherapy in intensive care: An updated systematic review. Chest. 144: 825–847, 2013. Toyoda Y, Bhama JK, Shigemura N, et al.: Efficacy of extracorporeal membrane oxygenation as a bridge to lung transplantation. J Thorac Cardiovasc Surg. 145: 1065–1071, 2013. Valapour M, Lehr CJ, Skeans MA, et al.: OPTN/SRTR 2020 Annual Data Report: Lung. Am J Transplant. 22: 438–518, 2022. Pasrija C, Mackowick KM, Raithel M, et al.: Ambulation with femoral arterial cannulation can be safely performed on venoarterial extracorporeal membrane oxygenation. Ann Thorac Surg. 107: 1389–1394, 2019. Wojack CA, VanBlarcom AG, Casida J: Ambulatory extracorporeal membrane oxygenation: Times are changing. AACN Adv Crit Care. 32: 434–442, 2021. Kearns SK, Hernandez OO: “Awake” extracorporeal membrane oxygenation as a bridge to lung transplant. AACN Adv Crit Care. 27: 293–300, 2016. Mohite PN, Sabashnikov A, Reed A, et al.: Extracorporeal life support in “awake” patients as a bridge to lung transplant. Thorac Cardiovasc Surg. 63: 699–705, 2015. Fuehner T, Kuehn C, Hadem J, et al.: Extracorporeal membrane oxygenation in awake patients as bridge to lung transplantation. Am J Respir Crit Care Med. 185: 763–768, 2012. |
| تواريخ الأحداث: | Date Created: 20240201 Date Completed: 20240701 Latest Revision: 20240909 |
| رمز التحديث: | 20240910 |
| DOI: | 10.1097/MAT.0000000000002154 |
| PMID: | 38300884 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1538-943X |
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| DOI: | 10.1097/MAT.0000000000002154 |