دورية أكاديمية
Self-Assembly of Rod-Coil Bottlebrush Copolymers into Degradable Nanodiscs with a UV-Triggered Self-Immolation Process.
| العنوان: | Self-Assembly of Rod-Coil Bottlebrush Copolymers into Degradable Nanodiscs with a UV-Triggered Self-Immolation Process. |
|---|---|
| المؤلفون: | Zeng H; Key Centre for Polymers and Colloids, School of Chemistry, The University of Sydney, 2006, Sydney, NSW, Australia., Liang X; Department of Chemistry and Department of Chemical and Biochemical Engineering, The University of Western Ontario, N6A 5B7, London, Ontario, Canada., Roberts DA; Key Centre for Polymers and Colloids, School of Chemistry, The University of Sydney, 2006, Sydney, NSW, Australia., Gillies ER; Department of Chemistry and Department of Chemical and Biochemical Engineering, The University of Western Ontario, N6A 5B7, London, Ontario, Canada., Müllner M; Key Centre for Polymers and Colloids, School of Chemistry, The University of Sydney, 2006, Sydney, NSW, Australia.; The University of Sydney Nano Institute (Sydney Nano), The University of Sydney, 2006, Sydney, NSW, Australia. |
| المصدر: | Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2024 Mar 22; Vol. 63 (13), pp. e202318881. Date of Electronic Publication: 2024 Feb 22. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 0370543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3773 (Electronic) Linking ISSN: 14337851 NLM ISO Abbreviation: Angew Chem Int Ed Engl Subsets: PubMed not MEDLINE; MEDLINE |
| أسماء مطبوعة: | Publication: <2004-> : Weinheim : Wiley-VCH Original Publication: Weinheim/Bergstr. : New York, : Verlag Chemie ; Academic Press, c1962- |
| مستخلص: | Polymer nanodiscs, especially with stimuli-responsive features, represent an unexplored frontier in the nanomaterial landscape. Such 2D nanomaterials are considered highly promising for advanced biomedicine applications. Herein, we designed a rod-coil copolymer architecture based on an amphiphilic, tadpole-like bottlebrush copolymer, which can directly self-assemble into core-shell nanodiscs in an aqueous environment. As the bottlebrush side chains are made of amorphous, UV-responsive poly(ethyl glyoxylate) (PEtG) chains, they can undergo rapid end-to-end self-immolation upon light irradiation. This triggered nanodisc disassembly can be used to boost small molecule release from the nanodisc core, which is further aided by a morphological change from discs to spheres. (© 2024 The Authors. Angewandte Chemie International Edition published by Wiley-VCH GmbH.) |
| References: | N. J. W. Penfold, J. Yeow, C. Boyer, S. P. Armes, ACS Macro Lett. 2019, 8, 1029-1054. J. Cao, Y. Tan, Y. Chen, L. Zhang, J. Tan, Macromol. Rapid Commun. 2021, 42, 2100498. T. Ravula, N. Z. Hardin, A. Ramamoorthy, Chem. Phys. Lipids 2019, 219, 45-49. J. Bariwal, H. Ma, G. A. Altenberg, H. Liang, Chem. Soc. Rev. 2022, 51, 1702-1728. M. D. Farrelly, L. L. Martin, S. H. Thang, Chem. Eur. J. 2021, 27, 12922-12939. K. Yasuhara, J. Arakida, T. Ravula, S. K. Ramadugu, B. Sahoo, J. I. Kikuchi, A. Ramamoorthy, J. Am. Chem. Soc. 2017, 139, 18657-18663. E. Prade, M. Mahajan, S.-C. Im, M. Zhang, K. A. Gentry, G. M. Anantharamaiah, L. Waskell, A. Ramamoorthy, Angew. Chem. 2018, 130, 8594-8598. B. R. Sahoo, T. Genjo, M. Bekier, S. J. Cox, A. K. Stoddard, M. Ivanova, K. Yasuhara, C. A. Fierke, Y. Wang, A. Ramamoorthy, Chem. Commun. 2018, 54, 12883-12886. K. Bavishi, T. Laursen, K. L. Martinez, B. L. Møller, E. A. Della Pia, Sci. Rep. 2016, 6, 29459. T. J. Knowles, R. Finka, C. Smith, Y. P. Lin, T. Dafforn, M. Overduin, J. Am. Chem. Soc. 2009, 131, 7484-7485. M. C. Fiori, Y. Jiang, W. Zheng, M. Anzaldua, M. J. Borgnia, G. A. Altenberg, H. Liang, Sci. Rep. 2017, 7, 15227. E. R. L. Brisson, M. J. H. Worthington, S. Kerai, M. Müllner, Chem. Soc. Rev. 2024, 53, 1984-2021. M. Nakano, K. Matsumoto, H. Matsuoka, H. Yamaoka, Macromolecules 1999, 32, 4023-4029. D. Richter, D. Schneiders, M. Monkenbusch, L. Willner, L. J. Fetters, J. S. Huang, M. Lin, K. Mortensen, B. Farago, Macromolecules 1997, 30, 1053-1068. F. Jia, F. Liang, Z. Yang, ACS Macro Lett. 2016, 5, 1344-1347. Y. Zhang, F. Jia, L. Tang, P. Zhou, B. Jiang, F. Liang, Z. Yang, Macromol. Rapid Commun. 2019, 40, 1900067. H. Zhu, Y. Cui, J. Wang, H. Qiu, RSC Adv. 2019, 9, 9443-9448. B. J. Toebes, D. A. Wilson, Soft Matter 2021, 17, 1724-1730. Q. Zhang, H. Fan, L. Zhang, Z. Jin, Macromolecules 2020, 53, 7025-7033. J. Zhu, S. Zhang, K. Zhang, X. Wang, J. W. Mays, K. L. Wooley, D. J. Pochan, Nat. Commun. 2013, 4, 2297. Z. Tong, Y. Xie, M. C. Arno, Y. Zhang, I. Manners, R. K. O'Reilly, A. P. Dove, Nat. Chem. 2023, 15, 824-831. R. Deng, X. Mao, S. Pearce, J. Tian, Y. Zhang, I. Manners, J. Am. Chem. Soc. 2022, 144, 19051-19059. L. Cao, I. Manners, M. A. Winnik, Macromolecules 2002, 35, 8258-8260. Z. Shi, Y. Wei, C. Zhu, J. Sun, Z. Li, Macromolecules 2018, 51, 6344-6351. X. Jin, F. Wu, J. Lin, C. Cai, L. Wang, J. Chen, L. Gao, Langmuir 2021, 37, 3148-3157. T. W. Schleuss, R. Abbel, M. Gross, D. Schollmeyer, H. Frey, M. Maskos, R. Berger, A. F. M. Kilbinger, Angew. Chem. Int. Ed. 2006, 45, 2969-2975. Y. Shi, W. Zhu, D. Yao, M. Long, B. Peng, K. Zhang, Y. Chen, ACS Macro Lett. 2014, 3, 70-73. L. Ren, F. Ke, Y. Chen, D. Liang, J. Huang, Macromolecules 2008, 41, 5295-5300. M. Long, Y. Shi, K. Zhang, Y. Chen, Macromol. Rapid Commun. 2016, 37, 605-609. X. Fu, L. Hosta-Rigau, R. Chandrawati, J. Cui, Chem 2018, 4, 2084-2107. T. Manouras, M. Vamvakaki, Polym. Chem. 2017, 8, 74-96. M. A. C. Stuart, W. T. S. Huck, J. Genzer, M. Müller, C. Ober, M. Stamm, G. B. Sukhorukov, I. Szleifer, V. V. Tsukruk, M. Urban, F. Winnik, S. Zauscher, I. Luzinov, S. Minko, Nat. Mater. 2010, 9, 101-113. Y. Xiao, X. Tan, Z. Li, K. Zhang, J. Mater. Chem. B 2020, 8, 6697-6709. O. Shelef, S. Gnaim, D. Shabat, J. Am. Chem. Soc. 2021, 143, 21177-21188. A. D. Wong, M. A. DeWit, E. R. Gillies, Adv. Drug Delivery Rev. 2012, 64, 1031-1045. A. Sagi, R. Weinstain, N. Karton, D. Shabat, J. Am. Chem. Soc. 2008, 130, 5434-5435. Z. Deng, E. R. Gillies, JACS Au 2023, 3, 2436-2450. T. Pelras, C. S. Mahon, M. Müllner, Angew. Chem. Int. Ed. 2018, 57, 6982-6994. M. Müllner, A. H. E. Müller, Polymer 2016, 98, 389-401. Y. Yan, Y. Shi, W. Zhu, Y. Chen, Polymer 2013, 54, 5634-5642. P. Zhao, Y. Yan, X. Feng, L. Liu, C. Wang, Y. Chen, Polymer 2012, 53, 1992-2000. S. Varlas, R. Keogh, Y. Xie, S. L. Horswell, J. C. Foster, R. K. O'Reilly, J. Am. Chem. Soc. 2019, 141, 20234-20248. H. Sun, S. Chen, X. Li, Y. Leng, X. Zhou, J. Du, Nat. Commun. 2022, 13, 2170. E. Carboni, K. Tschudi, J. Nam, X. Lu, A. W. K. Ma, AAPS PharmSciTech 2014, 15, 762-771. R. Agarwal, V. Singh, P. Jurney, L. Shi, S. V. Sreenivasan, K. Roy, Proc. Natl. Acad. Sci. USA 2013, 110, 17247-17252. G. Adriani, M. D. de Tullio, M. Ferrari, F. Hussain, G. Pascazio, X. Liu, P. Decuzzi, Biomaterials 2012, 33, 5504-5513. Y. Zhang, S. Tekobo, Y. Tu, Q. Zhou, X. Jin, S. A. Dergunov, E. Pinkhassik, B. Yan, ACS Appl. Mater. Interfaces 2012, 4, 4099-4105. J. Allen, K. Howell, J. J. van Netten, J. G. van Baal, M. Sorelli, C. Ince, L. Bocchi, R. Toy, E. Hayden, C. Shoup, H. Baskaran, E. Karathanasis, Nanotechnology 2011, 22, 115101. Y. Geng, P. Dalhaimer, S. Cai, R. Tsai, M. Tewari, T. Minko, D. E. Discher, Nat. Nanotechnol. 2007, 2, 249-255. S. Herrlich, S. Spieth, S. Messner, R. Zengerle, Adv. Drug Delivery Rev. 2012, 64, 1617-1627. B. Fan, E. R. Gillies, Mol. Pharm. 2017, 14, 2548-2559. A. Ishimoto, H. Sasako, M. Omori, K. Higashi, K. Ueda, K. Koyama, K. Moribe, Langmuir 2022, 38, 10454-10464. A. J. Gormley, J. Yeow, G. Ng, Ó. Conway, C. Boyer, R. Chapman, Angew. Chem. Int. Ed. 2018, 57, 1557-1562. A. Rabiee Kenaree, E. R. Gillies, Macromolecules 2018, 51, 5501-5510. G. E. Negri, T. J. Deming, ACS Macro Lett. 2016, 5, 1253-1256. T. N. Forder, P. G. Maschmeyer, H. Zeng, D. A. Roberts, Chem. Asian J. 2021, 16, 287-291. |
| معلومات مُعتمدة: | FT200100185 Australian Research Council; DE190100797 Australian Research Council; RGPIN 2016-04636 Natural Sciences and Engineering Research Council of Canada; CRC-2020-00101 Canada Research Chairs; DP220100452 Australian Research Council |
| فهرسة مساهمة: | Keywords: depolymerisation; drug loading; light-responsiveness; molecular polymer bottlebrushes; shape-transformation |
| تواريخ الأحداث: | Date Created: 20240206 Latest Revision: 20240318 |
| رمز التحديث: | 20240318 |
| DOI: | 10.1002/anie.202318881 |
| PMID: | 38320963 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder كن أول من يترك تعليقا!