دورية أكاديمية
أعرض في EDS

Clinical Trial Racial and Ethnic Disparities in Minimally Invasive Gynecologic Surgery.

التفاصيل البيبلوغرافية
العنوان: Clinical Trial Racial and Ethnic Disparities in Minimally Invasive Gynecologic Surgery.
المؤلفون: Sweterlitsch KM; Department of Obstetrics and Gynecology, Cedars-Sinai Medical Center (Drs. Sweterlitsch, Meyer, Hamilton, Truong, Wright, and Siedhoff), Los Angeles, California. Electronic address: Katherine.moran@cshs.org., Meyer R; Department of Obstetrics and Gynecology, Cedars-Sinai Medical Center (Drs. Sweterlitsch, Meyer, Hamilton, Truong, Wright, and Siedhoff), Los Angeles, California; The Dr. Pinchas Bornstein Talpiot Medical Leadership Program, Sheba Medical Center (Drs. Meyer and Ohayon), Tel Hashomer, Ramat-Gan, Israel., Ohayon A; The Dr. Pinchas Bornstein Talpiot Medical Leadership Program, Sheba Medical Center (Drs. Meyer and Ohayon), Tel Hashomer, Ramat-Gan, Israel., Levin G; Lady Davis Institute for cancer research, Jewish General Hospital, McGill University (Dr. Levin), Quebec, Canada., Hamilton K; Department of Obstetrics and Gynecology, Cedars-Sinai Medical Center (Drs. Sweterlitsch, Meyer, Hamilton, Truong, Wright, and Siedhoff), Los Angeles, California., Truong M; Department of Obstetrics and Gynecology, Cedars-Sinai Medical Center (Drs. Sweterlitsch, Meyer, Hamilton, Truong, Wright, and Siedhoff), Los Angeles, California., Wright KN; Department of Obstetrics and Gynecology, Cedars-Sinai Medical Center (Drs. Sweterlitsch, Meyer, Hamilton, Truong, Wright, and Siedhoff), Los Angeles, California., Siedhoff MT; Department of Obstetrics and Gynecology, Cedars-Sinai Medical Center (Drs. Sweterlitsch, Meyer, Hamilton, Truong, Wright, and Siedhoff), Los Angeles, California.
المصدر: Journal of minimally invasive gynecology [J Minim Invasive Gynecol] 2024 May; Vol. 31 (5), pp. 414-422. Date of Electronic Publication: 2024 Feb 05.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 101235322 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1553-4669 (Electronic) Linking ISSN: 15534650 NLM ISO Abbreviation: J Minim Invasive Gynecol Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Philadelphia, PA : Elsevier, c2005-
مواضيع طبية MeSH: Gynecologic Surgical Procedures*/statistics & numerical data , Gynecologic Surgical Procedures*/methods , Minimally Invasive Surgical Procedures*/statistics & numerical data, Female ; Humans ; Cross-Sectional Studies ; Ethnicity ; Healthcare Disparities/ethnology ; Healthcare Disparities/statistics & numerical data ; Randomized Controlled Trials as Topic ; United States ; Racial Groups
مستخلص: Study Objective: To study racial and ethnic disparities in randomized controlled trials (RCTs) in minimally invasive gynecologic surgery (MIGS).
Design: Cross-sectional study.
Setting: Online review of all published MIGS RCTs in high-impact journals from 2012 to 2023.
Patients: Journals included all first quartile obstetrics and gynecology journals, as well as The New England Journal of Medicine, The Lancet, The British Medical Journal, and The Journal of the American Medical Association. The National Institutes of Health's PubMed and the ClinicalTrials.gov websites were queried using the following search terms from the American Board of Obstetrics and Gynecology's certifying examination bulletin 2022 to obtain relevant trials: adenomyosis, adnexal surgery, abnormal uterine bleeding, cystectomy, endometriosis, fibroids, gynecology, hysterectomy, hysteroscopy, laparoscopy, leiomyoma, minimally invasive gynecology, myomectomy, ovarian cyst, and robotic surgery.
Interventions: The US Census Bureau data were used to estimate the expected number of participants. We calculated the enrollment ratio (ER) of actual to expected participants for US trials with available race and ethnicity data.
Measurements and Main Results: A total of 352 RCTs were identified. Of these, race and/or ethnicity data were available in 65 studies (18.5%). We analyzed the 46 studies that originated in the United States, with a total of 4645 participants. Of these RCTs, only 8 (17.4%) reported ethnicity in addition to race. When comparing published RCT data with expected proportions of participants, White participants were overrepresented (70.8% vs. 59.6%; ER, 1.66; 95% confidence interval [CI], 1.52-1.81), as well as Black or African American participants (15.4% vs. 13.7%; ER, 1.15; 95% CI, 1.03-1.29). Hispanic (6.7% vs. 19.0%; ER, 0.31; 95% CI, 0.27-0.35), Asian (1.7% vs. 6.1%; ER, 0.26; 95% CI, 0.20-0.34), Native Hawaiian or other Pacific Islander (0.1% vs. 0.3%; ER, 0.21; 95% CI, 0.06-0.74), and Indian or Alaska Native participants (0.2% vs. 1.3%; ER, 0.16; 95% CI, 0.08-0.32) were underrepresented. When comparing race/ethnicity proportions in the 20 states where the RCTs were conducted, Black or African American participants were underrepresented.
Conclusion: In MIGS RCTs conducted in the United States, White and Black or African American participants are overrepresented compared with other races, and ethnicity is characterized in fewer than one-fifth of trials. Efforts should be made to improve racial and ethnic recruitment equity and reporting in future MIGS RCTs.
(Copyright © 2024 AAGL. Published by Elsevier Inc. All rights reserved.)
فهرسة مساهمة: Keywords: Clinical trial; Disparities; Ethnicity; Minimally invasive gynecologic surgery; Race
تواريخ الأحداث: Date Created: 20240207 Date Completed: 20240505 Latest Revision: 20240508
رمز التحديث: 20240509
DOI: 10.1016/j.jmig.2024.01.019
PMID: 38325584
قاعدة البيانات: MEDLINE
الوصف
تدمد:1553-4669
DOI:10.1016/j.jmig.2024.01.019