دورية أكاديمية
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Transcriptome Analysis Reveals the Mechanisms of Accumulation and Conversion of Folate Derivatives during Germination of Quinoa ( Chenopodium quinoa Willd.) Seeds.

التفاصيل البيبلوغرافية
العنوان: Transcriptome Analysis Reveals the Mechanisms of Accumulation and Conversion of Folate Derivatives during Germination of Quinoa ( Chenopodium quinoa Willd.) Seeds.
المؤلفون: He Y; College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China., Li C; College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China., Yang M; College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China., Wang C; Hebei Tongfu Group Co., Ltd., Shijiazhuang 050000, China., Guo H; Hebei Tongfu Group Co., Ltd., Shijiazhuang 050000, China., Liu J; College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China., Liu H; College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China.
المصدر: Journal of agricultural and food chemistry [J Agric Food Chem] 2024 Feb 21; Vol. 72 (7), pp. 3800-3813. Date of Electronic Publication: 2024 Feb 07.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0374755 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5118 (Electronic) Linking ISSN: 00218561 NLM ISO Abbreviation: J Agric Food Chem Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Washington, American Chemical Society.
مواضيع طبية MeSH: Chenopodium quinoa*/genetics , Chenopodium quinoa*/chemistry, Folic Acid ; Seeds/genetics ; Seeds/chemistry ; Gene Expression Profiling ; Carbon/analysis
مستخلص: Folate was enriched during quinoa germination, while molecular mechanisms were not well understood. In this study, three quinoa varieties were selected for germination, and changes in substrate content and enzyme activity of the folate biosynthesis pathway were monitored. 5-Methyltetrahydrofolate (5-CH 3 -THF) and 5-formyltetrahydrofolate (5-CHO-THF) were significantly enriched in quinoa sprouts. Among the selected varieties, QL-2 exhibited the lowest content of the oxidation product MeFox and the highest total folate content. Based on transcriptome analysis, the p -ABA branch was found to be crucial for folate accumulation, while the pterin branch served as a key control point for the one carbon pool by folate pathway, which limited further folate biosynthesis. In the one carbon pool by folate pathway, genes CqMTHFR and CqAMT significantly contributed to the enrichment of 5-CH 3 -THF and 5-CHO-THF. Findings gained here would facilitate the potential application of quinoa sprouts as an alternative strategy for folate supplementation.
فهرسة مساهمة: Keywords: 5-CH3-THF; 5-CHO-THF; folate biosynthesis; germination; quinoa (Chenopodium quinoa Willd.); transcriptome analysis
المشرفين على المادة: 935E97BOY8 (Folic Acid)
7440-44-0 (Carbon)
تواريخ الأحداث: Date Created: 20240208 Date Completed: 20240222 Latest Revision: 20240222
رمز التحديث: 20240222
DOI: 10.1021/acs.jafc.3c08209
PMID: 38327020
قاعدة البيانات: MEDLINE
الوصف
تدمد:1520-5118
DOI:10.1021/acs.jafc.3c08209