دورية أكاديمية
أعرض في EDS

The effect of acupuncture on oxidative stress in animal models of vascular dementia: a systematic review and meta-analysis.

التفاصيل البيبلوغرافية
العنوان: The effect of acupuncture on oxidative stress in animal models of vascular dementia: a systematic review and meta-analysis.
المؤلفون: Bao QN; Department of Traditional Chinese Medicine, The First People's Hospital of Yunnan Province, Kunming, Yunnan, China.; The Affiliated Hospital of Kunming University of Science and Technology, Kunming, Yunnan, China.; School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China., Xia MZ; School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China., Xiong J; Department of Rehabilitation, West China Hospital of Sichuan University, Chengdu, Sichuan, China., Liu YW; Department of Rehabilitation, West China Hospital of Sichuan University, Chengdu, Sichuan, China., Li YQ; School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China., Zhang XY; School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China., Chen ZH; School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China., Yao J; School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China., Wu KX; School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China., Zhong WQ; School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China., Xu SJ; Department of Traditional Chinese Medicine, The First People's Hospital of Yunnan Province, Kunming, Yunnan, China. xinyun1220@126.com.; The Affiliated Hospital of Kunming University of Science and Technology, Kunming, Yunnan, China. xinyun1220@126.com., Yin ZH; School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China. yinzihan@stu.cdutcm.edu.cn., Liang FR; School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China. acuresearch@126.com.
المصدر: Systematic reviews [Syst Rev] 2024 Feb 08; Vol. 13 (1), pp. 59. Date of Electronic Publication: 2024 Feb 08.
نوع المنشور: Meta-Analysis; Systematic Review; Journal Article
اللغة: English
بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101580575 Publication Model: Electronic Cited Medium: Internet ISSN: 2046-4053 (Electronic) Linking ISSN: 20464053 NLM ISO Abbreviation: Syst Rev Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : BioMed Central
مواضيع طبية MeSH: Acupuncture Therapy*/methods , Dementia, Vascular*/therapy, Animals ; Models, Animal ; Oxidative Stress ; Reactive Oxygen Species/metabolism
مستخلص: Background: Growing evidence showed that acupuncture may improve cognitive function by reducing oxidative stress, key to the pathogenesis in vascular dementia (VaD), but this is yet to be systematically analysed. This study aimed to summarize and evaluate the effect of acupuncture on oxidative stress in animal models of VaD.
Method: Eight databases including PubMed, Embase, Web of Science, Cochrane library, CNKI, Wan Fang, CBM, and VIP were searched since their establishment until April 2023, for studies that reported the effect of acupuncture on oxidative stress in VaD animal models. Relevant literature was screened, and information was extracted by two reviewers. The primary outcomes were the levels of oxidative stress indicators. The methodological quality was assessed via the SYRCLE Risk of Bias Tool. Statistical analyses were performed using the RevMan and Stata software.
Results: In total, 22 studies with 747 animals were included. The methodology of most studies had flaws or uncertainties. The meta-analysis indicated that, overall, acupuncture significantly reduced the expression of pro-oxidants including reactive oxygen species (standardized mean differences [SMDs] = -4.29, 95% confidence interval [CI]: -6.26, -2.31), malondialdehyde (SMD = -2.27, 95% CI: -3.07, -1.47), nitric oxide (SMD = -0.85, 95% CI: -1.50, -0.20), and nitric oxide synthase (SMD = -1.01, 95% CI: -1.69, -0.34) and enhanced the levels of anti-oxidants including super oxide dismutase (SMD = 2.80, 95% CI: 1.98, 3.61), glutathione peroxidase (SMD = 1.32, 95% CI: -0.11, 2.76), and catalase (SMD = 1.31, 95% CI: 0.05, 2.58) in VaD animal models. In subgroup analyses, acupuncture showed significant effects on most variables. Only partial modelling methods and treatment duration could interpret the heterogeneity of some outcomes.
Conclusion: Acupuncture may inhibit oxidative stress to improve cognitive deficits in animal models of VaD. Nevertheless, the methodological quality is unsatisfactory. More high-quality research with a rigorous design and further experimental researches and clinical trials are needed to confirm these findings.
Systematic Review Registration: This study was registered in PROSPERO (CRD42023411720).
(© 2024. The Author(s).)
References: Int J Mol Sci. 2021 Oct 31;22(21):. (PMID: 34769277)
Front Pharmacol. 2022 Sep 05;13:948889. (PMID: 36133823)
Int J Mol Sci. 2017 Dec 20;18(12):. (PMID: 29261130)
N Engl J Med. 2013 Aug 1;369(5):489. (PMID: 23902509)
Free Radic Biol Med. 2014 Jan;66:75-87. (PMID: 23899494)
Neuroscience. 2018 May 21;379:281-291. (PMID: 29592844)
Neurochem Int. 2016 Jan;92:35-42. (PMID: 26682902)
BMC Med Res Methodol. 2014 Mar 26;14:43. (PMID: 24667063)
Maturitas. 2017 May;99:66-72. (PMID: 28364871)
J Neurol Sci. 2014 Feb 15;337(1-2):156-61. (PMID: 24321755)
Neurochem Int. 2014 Jan;65:23-9. (PMID: 24361538)
Free Radic Biol Med. 2015 Dec;89:1077-84. (PMID: 26546103)
Chin J Integr Med. 2014 Sep;20(9):661-6. (PMID: 24155069)
Int J Mol Sci. 2017 Nov 22;18(11):. (PMID: 29165383)
Front Neurosci. 2022 Dec 14;16:1053283. (PMID: 36590305)
Lancet. 2015 Oct 24;386(10004):1698-706. (PMID: 26595643)
Neuropharmacology. 2018 May 15;134(Pt B):226-239. (PMID: 29273521)
Front Aging Neurosci. 2022 Aug 18;14:952181. (PMID: 36062145)
CNS Neurosci Ther. 2018 Jan;24(1):39-46. (PMID: 29110407)
Oxid Med Cell Longev. 2019 Nov 11;2019:9613090. (PMID: 31827713)
J Alzheimers Dis. 2009;17(2):245-57. (PMID: 19221412)
BMJ. 2021 Mar 29;372:n71. (PMID: 33782057)
J Cell Biol. 2018 Jun 4;217(6):1915-1928. (PMID: 29669742)
J Neurol Sci. 2002 Nov 15;203-204:195-7. (PMID: 12417383)
CNS Neurosci Ther. 2018 Dec;24(12):1264-1274. (PMID: 30278105)
Zhen Ci Yan Jiu. 2021 Oct 25;46(10):851-6. (PMID: 34698459)
Stroke. 2005 Mar;36(3):619-24. (PMID: 15692125)
BMJ Open Sci. 2020 Apr 15;4(1):e100046. (PMID: 35047688)
J Alzheimers Dis. 2016 Sep 6;54(2):427-43. (PMID: 27567871)
Seizure. 2021 Oct;91:278-286. (PMID: 34252880)
Antioxid Redox Signal. 2014 Aug 1;21(4):533-50. (PMID: 24294978)
Biomed Res Int. 2014;2014:908915. (PMID: 25089278)
Front Physiol. 2018 Jul 03;9:806. (PMID: 30018565)
Cell Calcium. 2004 Sep-Oct;36(3-4):265-75. (PMID: 15261482)
Curr Pharm Des. 2020;26(34):4246-4260. (PMID: 32640953)
Oxid Med Cell Longev. 2017;2017:6501046. (PMID: 28698768)
BMC Geriatr. 2019 Apr 15;19(1):104. (PMID: 30987591)
Free Radic Biol Med. 2023 Jun;202:62-75. (PMID: 36997099)
Antioxid Redox Signal. 2018 Apr 1;28(10):987-1007. (PMID: 28298143)
Neurol Sci. 2013 Mar;34(3):305-12. (PMID: 22391677)
Complement Ther Med. 2022 Nov;70:102857. (PMID: 35843473)
Clin Sci (Lond). 2017 Jun 1;131(11):1059-1068. (PMID: 28515342)
J Cereb Blood Flow Metab. 2016 Jan;36(1):172-86. (PMID: 26174330)
Evid Based Complement Alternat Med. 2021 Apr 26;2021:6624976. (PMID: 33995547)
Oxid Med Cell Longev. 2019 Oct 13;2019:5080843. (PMID: 31737171)
Zhen Ci Yan Jiu. 2022 Apr 25;47(4):298-304. (PMID: 35486008)
Sci Rep. 2023 Apr 5;13(1):5595. (PMID: 37019901)
J Neuroimmune Pharmacol. 2014 Sep;9(4):492-507. (PMID: 24903518)
Sci Rep. 2015 Dec 10;5:17981. (PMID: 26656460)
Neuron. 2013 Nov 20;80(4):844-66. (PMID: 24267647)
J Alzheimers Dis. 2021;82(1):235-248. (PMID: 34057086)
ScientificWorldJournal. 2015;2015:161439. (PMID: 26495416)
J Cereb Blood Flow Metab. 2023 Nov;43(2_suppl):18-36. (PMID: 36883344)
Zhongguo Zhen Jiu. 2021 Sep 12;41(9):979-83. (PMID: 34491646)
Theranostics. 2020 Feb 3;10(6):2832-2848. (PMID: 32194838)
فهرسة مساهمة: Keywords: Acupuncture; Animal model; Meta-analysis; Oxidative stress; Vascular dementia
المشرفين على المادة: 0 (Reactive Oxygen Species)
تواريخ الأحداث: Date Created: 20240208 Date Completed: 20240220 Latest Revision: 20240220
رمز التحديث: 20240221
مُعرف محوري في PubMed: PMC10851587
DOI: 10.1186/s13643-024-02463-x
PMID: 38331921
قاعدة البيانات: MEDLINE
الوصف
تدمد:2046-4053
DOI:10.1186/s13643-024-02463-x