دورية أكاديمية
Testicular volume is a noninvasive predictor of sperm retrieval failure in idiopathic nonobstructive azoospermia.
| العنوان: | Testicular volume is a noninvasive predictor of sperm retrieval failure in idiopathic nonobstructive azoospermia. |
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| المؤلفون: | Xiao H; Department of Andrology and Sexual Medicine, First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, China., Tang SX, Yao RJ, Ding YL, Yang P, Chen Q, Huang HL, Chen X, Zhou HL |
| المصدر: | Asian journal of andrology [Asian J Androl] 2024 Jul 01; Vol. 26 (4), pp. 421-425. Date of Electronic Publication: 2024 Feb 13. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Shanghai Materia Medica Country of Publication: China NLM ID: 100942132 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1745-7262 (Electronic) Linking ISSN: 1008682X NLM ISO Abbreviation: Asian J Androl Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Shanghai : Shanghai Materia Medica Original Publication: Beijing : Science Press, |
| مواضيع طبية MeSH: | Azoospermia*/pathology , Sperm Retrieval* , Testis*/pathology , Testis*/surgery , Testis*/diagnostic imaging, Humans ; Male ; Adult ; Organ Size ; Treatment Failure ; Prognosis ; Retrospective Studies ; ROC Curve ; Seminiferous Tubules/pathology |
| مستخلص: | We investigated the prognostic importance of noninvasive factors in predicting sperm retrieval failure in idiopathic nonobstructive azoospermia (iNOA). We studied 193 patients with nonobstructive azoospermia who underwent microsurgical testicular sperm extraction. The Chi-square test and Mann-Whitney U tests for clinical parameters and seminiferous tubule distribution were used for between-group comparisons. A logistic regression analysis was conducted to identify predictors of retrieval failure. Area under the receiver operating characteristic curve for each variable was evaluated, and the net clinical benefit was calculated using a clinical decision curve. Patients with iNOA had a lower sperm retrieval rate than those with known causes. Moreover, testicular volume was an independent factor affecting sperm extraction outcomes (odds ratio = 0.79, P < 0.05). The testicular volume cut-off value was 6.5 ml (area under the curve: 0.694). The patients with iNOA were categorized into two groups on the basis of the distribution of seminiferous tubules observed. The sperm retrieval rate and testicular volume were significantly different between the groups with a uniform or heterogeneous tubule distribution. There was also a significant association between a uniform tubule distribution and testicular volume. In conclusion, a testicular volume of more than 6.5 ml effectively predicts microsurgical testicular sperm extraction failure due to a uniform tubule distribution in patients with iNOA. (Copyright © 2024 Copyright: ©The Author(s)(2024).) |
| References: | J Urol. 2014 Jan;191(1):175-8. (PMID: 23911635) Hum Reprod Update. 2018 Jul 1;24(4):442-454. (PMID: 29726895) Fertil Steril. 1996 Jul;66(1):110-7. (PMID: 8752620) Hum Reprod. 2023 Aug 1;38(8):1464-1472. (PMID: 37322566) Eur Urol. 2022 Oct;82(4):377-384. (PMID: 35599183) Asian J Androl. 2019 Mar-Apr;21(2):109-114. (PMID: 30381580) Front Endocrinol (Lausanne). 2022 Oct 17;13:1006208. (PMID: 36325443) Transl Androl Urol. 2019 Aug;8(4):366-373. (PMID: 31555560) Lancet. 2021 Jan 23;397(10271):319-333. (PMID: 33308486) Basic Clin Androl. 2019 Jul 15;29:11. (PMID: 31338196) Clinics (Sao Paulo). 2013;68 Suppl 1:15-26. (PMID: 23503951) Asian J Androl. 2023 Feb 07;:. (PMID: 36814170) Medicine (Baltimore). 2020 May;99(18):e19934. (PMID: 32358364) Asian J Androl. 2023 Jan-Feb;25(1):38-42. (PMID: 35645045) |
| SCR Disease Name: | Azoospermia, Nonobstructive |
| تواريخ الأحداث: | Date Created: 20240214 Date Completed: 20240701 Latest Revision: 20240728 |
| رمز التحديث: | 20240728 |
| مُعرف محوري في PubMed: | PMC11280197 |
| DOI: | 10.4103/aja202379 |
| PMID: | 38353461 |
| قاعدة البيانات: | MEDLINE |
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