دورية أكاديمية
Efficacy and safety of a panthenol-enriched mask for individuals with distinct impaired skin barrier subtypes.
| العنوان: | Efficacy and safety of a panthenol-enriched mask for individuals with distinct impaired skin barrier subtypes. |
|---|---|
| المؤلفون: | Zhang X; L'Oreal China, Shanghai, China., Tao H; L'Oreal China, Shanghai, China., Deng Y; Second Affiliated Hospital of Chongqing Medical University, Chongqing, China., He X; L'Oreal China, Shanghai, China., Zhang Z; L'Oreal China, Shanghai, China., Zhong L; L'Oreal China, Shanghai, China., Wen Y; L'Oreal China, Shanghai, China. |
| المصدر: | Journal of cosmetic dermatology [J Cosmet Dermatol] 2024 Jun; Vol. 23 (6), pp. 2109-2116. Date of Electronic Publication: 2024 Feb 17. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Blackwell Science Country of Publication: England NLM ID: 101130964 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1473-2165 (Electronic) Linking ISSN: 14732130 NLM ISO Abbreviation: J Cosmet Dermatol Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Oxford, UK : Blackwell Science, c2002- |
| مواضيع طبية MeSH: | Pantothenic Acid*/administration & dosage , Pantothenic Acid*/adverse effects , Pantothenic Acid*/analogs & derivatives , Water Loss, Insensible*/drug effects , Acne Vulgaris*/drug therapy, Humans ; Female ; Adult ; Male ; Young Adult ; Sebum/metabolism ; Sebum/drug effects ; Middle Aged ; Treatment Outcome ; Skin/drug effects ; Adolescent ; Administration, Cutaneous ; Erythema/etiology ; Erythema/chemically induced |
| مستخلص: | Background: The protection for different skin types with impaired skin barrier in the market is insufficient. Aim: To evaluate the efficacy and safety of a panthenol-enriched mask (La Roche-Posay Mask Pro) in addressing various skin barrier impairment subgroups, including dry sensitive, oily sensitive, and oily acne skin. Methods: A total of 177 participants were enrolled in the study and divided into three subgroups based on their skin type. Participants used the mask following the specified protocol, with measurements taken for skin hydration, transepidermal water loss (TEWL), sebum content, and skin redness-factors that are directly influenced by skin barrier function. Assessments were conducted at baseline and after 1 day (tested 15 min post-application), 7 days, and 14 days of application using Sebumeter, Tewameter, Corneometer, Mexameter, and VISIA. Results: Results showed significant improvements in skin parameters across all subgroups. In the dry sensitive skin subgroup, the mask increased skin hydration, sebum content, and reduced redness. For the oily sensitive skin subgroup, the mask regulated sebum production and improved skin hydration. In the oily acne skin subgroup, the mask reduced sebum content, redness, TEWL, and post-inflammatory erythema and hyperpigmentation. Tolerance was excellent for all skin types, with no adverse reactions observed. Conclusions: This study highlights the efficacy and safety of the panthenol-enriched LRP Mask Pro for individuals with distinct skin barrier impairment subgroups. The mask's versatile formulation and proven efficacy make it a valuable skincare product for addressing various skin concerns and achieving healthier, more balanced skin. (© 2024 L'Oréal China. Journal of Cosmetic Dermatology published by Wiley Periodicals LLC.) |
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| معلومات مُعتمدة: | L'Oreal China |
| فهرسة مساهمة: | Keywords: mask; panthenol; skin barrier |
| المشرفين على المادة: | 0 (dexpanthenol) |
| تواريخ الأحداث: | Date Created: 20240217 Date Completed: 20240518 Latest Revision: 20240518 |
| رمز التحديث: | 20240518 |
| DOI: | 10.1111/jocd.16231 |
| PMID: | 38366684 |
| قاعدة البيانات: | MEDLINE |
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