دورية أكاديمية
Magnesium Disorders: Core Curriculum 2024.
| العنوان: | Magnesium Disorders: Core Curriculum 2024. |
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| المؤلفون: | Adomako EA; Division of Nephrology and Hypertension, Department of Internal Medicine, Jared Grantham Kidney Institute, University of Kansas Medical Center, Kansas City, Kansas., Yu ASL; Division of Nephrology and Hypertension, Department of Internal Medicine, Jared Grantham Kidney Institute, University of Kansas Medical Center, Kansas City, Kansas. Electronic address: ayu@kumc.edu. |
| المصدر: | American journal of kidney diseases : the official journal of the National Kidney Foundation [Am J Kidney Dis] 2024 Jun; Vol. 83 (6), pp. 803-815. Date of Electronic Publication: 2024 Feb 17. |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: W.B. Saunders Country of Publication: United States NLM ID: 8110075 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1523-6838 (Electronic) Linking ISSN: 02726386 NLM ISO Abbreviation: Am J Kidney Dis Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Philadelphia Pa : W.B. Saunders Original Publication: New York, N.Y. : Grune & Stratton, c1981- |
| مواضيع طبية MeSH: | Magnesium*/blood , Magnesium Deficiency*, Humans ; Sodium-Glucose Transporter 2 Inhibitors/therapeutic use |
| مستخلص: | Magnesium is ubiquitous in nature. It sits at the origin of the food chain, occupying the center of chlorophyl in plants. In humans, magnesium is critical to diverse molecular and catalytic processes, including energy transfer and maintenance of the genome. Despite its abundance, hypomagnesemia is common and often goes undiagnosed. This is in spite of epidemiologic data linking low magnesium with chronic diseases including diabetes mellitus. Clinically significant hypermagnesemia is encountered less frequently, but the presentation may be dramatic. Advances in molecular biology and the elucidation of the genetic causes of magnesium disorders have enhanced our understanding of their pathophysiology. Treatment approaches are also changing. The repurposing of newer medications, such as sodium/glucose cotransporter 2 inhibitors, offers new therapeutic options. In this review we integrate knowledge in this rapidly evolving field to provide clinicians and trainees with a resource for approaching common clinical scenarios involving magnesium disorders. (Copyright © 2024 The Authors. Published by Elsevier Inc. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Hypermagnesemia; TRPM6; hypomagnesemia; magnesium supplement; magnesium transport |
| المشرفين على المادة: | I38ZP9992A (Magnesium) 0 (Sodium-Glucose Transporter 2 Inhibitors) |
| تواريخ الأحداث: | Date Created: 20240219 Date Completed: 20240523 Latest Revision: 20240808 |
| رمز التحديث: | 20240809 |
| DOI: | 10.1053/j.ajkd.2023.10.017 |
| PMID: | 38372687 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 1523-6838 |
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| DOI: | 10.1053/j.ajkd.2023.10.017 |