دورية أكاديمية
أعرض في EDS

Osteomyelitis by Microsporum canis and Staphylococcus spp. in cat (Felis catus) - case report.

التفاصيل البيبلوغرافية
العنوان: Osteomyelitis by Microsporum canis and Staphylococcus spp. in cat (Felis catus) - case report.
المؤلفون: Soares FO; Hospital Veterinário Uniube, Universidade de Uberaba, Uberaba, Minas Gerais, Brazil., Rosado IR; Hospital Veterinário Uniube, Universidade de Uberaba, Uberaba, Minas Gerais, Brazil., Sousa MVC; Laboratório de Patologia Animal - PAVET, Universidade de Uberaba, Uberaba, Minas Gerais, Brazil., Dumont CF; Laboratório de Epidemiologia Molecular - LEPIMOL, Universidade Federal de Uberlândia, Uberlândia, Minas Gerais, Brazil. carolfdumont@gmail.com.; Programa de Pós-Graduação em Ciências Veterinárias, Universidade Federal de Uberlândia, Av. Ceará, s/n, Bloco 2D43, Uberlândia, CC 38402-018, Brazil. carolfdumont@gmail.com., Bittar JFF; Hospital Veterinário Uniube, Universidade de Uberaba, Uberaba, Minas Gerais, Brazil., Martin I; Hospital Veterinário Uniube, Universidade de Uberaba, Uberaba, Minas Gerais, Brazil., Beletti ME; Laboratório de Epidemiologia Molecular - LEPIMOL, Universidade Federal de Uberlândia, Uberlândia, Minas Gerais, Brazil., Melo RT; Laboratório de Epidemiologia Molecular - LEPIMOL, Universidade Federal de Uberlândia, Uberlândia, Minas Gerais, Brazil., Alves EGL; Hospital Veterinário Uniube, Universidade de Uberaba, Uberaba, Minas Gerais, Brazil.
المصدر: BMC veterinary research [BMC Vet Res] 2024 Feb 19; Vol. 20 (1), pp. 58. Date of Electronic Publication: 2024 Feb 19.
نوع المنشور: Case Reports; Journal Article
اللغة: English
بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101249759 Publication Model: Electronic Cited Medium: Internet ISSN: 1746-6148 (Electronic) Linking ISSN: 17466148 NLM ISO Abbreviation: BMC Vet Res Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : BioMed Central, 2005-
مواضيع طبية MeSH: Dermatomycoses*/veterinary , Osteomyelitis*/drug therapy , Osteomyelitis*/veterinary , Cat Diseases*/drug therapy , Microsporum*, Cats ; Female ; Animals ; Quality of Life ; Antifungal Agents/therapeutic use
مستخلص: Background: Staphylococcus spp and Microsporum canis are zoonotic microorganisms which can cause infections and systemic diseases. The bone infection is usually caused by invasion of pathogen through the hematologic route. Mixed osteomyelitis caused by bacteria and fungi is rare, and to date, there have been no reports of mixed osteomyelitis with Staphylococcus spp. and Microsporum canis.
Case Presentation: This essay reports an atypical presentation of mixed osteomyelitis (Staphylococcus spp. and Microsporum canis) in a domestic cat. A 15-month-old female Persian cat was presented to a veterinary service; the main complaint was the appearance of a nodule in the mandibular ventral rostral region. A radiographic exam performed on the animal showed proliferative and osteolytic bone lesions. The patient was submitted to a biopsy for histopathological evaluation, along with bacterial and fungal cultures. Results showed mixed osteomyelitis by Staphylococcus spp. and Microsporum canis. Microbial Sensitivity Test was performed to choose a more suitable treatment. Two surgical procedures were executed to resect and curette the lesion, and treatments with anti-inflammatory, antibiotic, and antifungal drugs were established, showing a positive clinical evolution. After 8 months of treatment, the patient's owner moved to a different city, and the animal was seen by other veterinarians, who followed along with the same treatment. However, due to complications and a diminishing quality of life over 4 years of diagnosis, the patient was euthanized.
Conclusion: Given the above, mixed osteomyelitis is difficult to treat and can cause losses of life quality resulting death, especially in infections where M. canis is the agent causing the disease. Bacterial osteomyelitis is more frequently reported. But the lack of investigation of microorganisms other than bacteria, such as fungal cases, may imply in underdiagnosed cases. Treatment of osteomyelitis can be difficult considering the difficulties in isolating the pathological agent, resistance to the drug used, prolonged treatment time, and cost.
(© 2024. The Author(s).)
References: Vet Q. 2022 Dec;42(1):1-11. (PMID: 34936853)
J Foot Ankle Surg. 2014 Jul-Aug;53(4):480-4. (PMID: 24713493)
Mycoses. 2021 Apr;64(4):340-348. (PMID: 33217082)
J Vet Diagn Invest. 2014 Jul;26(4):580-584. (PMID: 24821693)
Clin Microbiol Infect. 2012 Mar;18(3):268-81. (PMID: 21793988)
J Am Acad Dermatol. 1994 Jun;30(6):1021-2. (PMID: 8188866)
J Cutan Pathol. 2007 May;34(5):431-4. (PMID: 17448202)
Diagnostics (Basel). 2022 Jan 14;12(1):. (PMID: 35054368)
J Feline Med Surg. 2020 Feb;22(2):129-137. (PMID: 30784342)
Infect Dis Clin North Am. 2017 Jun;31(2):325-338. (PMID: 28483044)
Aust Vet J. 1979 Dec;55(12):587-91. (PMID: 539942)
Vet Dermatol. 2001 Aug;12(4):203-7. (PMID: 11493404)
Vet J. 2019 Aug;250:44-54. (PMID: 31383419)
BMC Surg. 2022 May 4;22(1):156. (PMID: 35509041)
BMC Vet Res. 2012 Dec 06;8:239. (PMID: 23216681)
Vet Dermatol. 2011 Apr;22(2):181-7. (PMID: 21114561)
J Feline Med Surg. 2009 Oct;11(10):878-80. (PMID: 19762260)
Vet Pathol. 2015 Sep;52(5):910-8. (PMID: 26113612)
Vet Clin North Am Small Anim Pract. 2010 Nov;40(6):1171-88. (PMID: 20933143)
J Feline Med Surg. 2018 Oct;20(10):985-996. (PMID: 29256743)
Vet Dermatol. 2006 Oct;17(5):327-31. (PMID: 16961818)
J Vet Intern Med. 1987 Oct-Dec;1(4):158-62. (PMID: 3506100)
Am J Clin Pathol. 1955 Aug;25(8):975-9. (PMID: 14398663)
JFMS Open Rep. 2016 Sep 30;2(2):2055116916668199. (PMID: 28491435)
Pathogens. 2022 Aug 23;11(9):. (PMID: 36145389)
فهرسة مساهمة: Keywords: Domestic cat; Mandible; Microbial sensitivity test; Osteomyelitis
المشرفين على المادة: 0 (Antifungal Agents)
SCR Organism: Microsporum canis
تواريخ الأحداث: Date Created: 20240219 Date Completed: 20240221 Latest Revision: 20240222
رمز التحديث: 20240222
مُعرف محوري في PubMed: PMC10875912
DOI: 10.1186/s12917-024-03904-4
PMID: 38374006
قاعدة البيانات: MEDLINE
الوصف
تدمد:1746-6148
DOI:10.1186/s12917-024-03904-4