دورية أكاديمية
أعرض في EDS

Patient Sex Mediates the Influence of Patient Age on Superior Canal Dehiscence Repair Outcome.

التفاصيل البيبلوغرافية
العنوان: Patient Sex Mediates the Influence of Patient Age on Superior Canal Dehiscence Repair Outcome.
المؤلفون: Yang HH; Department of Head and Neck Surgery, David Geffen School of Medicine at University of California, Los Angeles, California, U.S.A., Yang I; Department of Neurosurgery, David Geffen School of Medicine at University of California, Los Angeles, California, U.S.A., Gopen QS; Department of Head and Neck Surgery, David Geffen School of Medicine at University of California, Los Angeles, California, U.S.A.
المصدر: The Laryngoscope [Laryngoscope] 2024 Jul; Vol. 134 (7), pp. 3363-3370. Date of Electronic Publication: 2024 Feb 21.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 8607378 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1531-4995 (Electronic) Linking ISSN: 0023852X NLM ISO Abbreviation: Laryngoscope Subsets: MEDLINE
أسماء مطبوعة: Publication: <2009- >: Philadelphia, PA : Wiley-Blackwell
Original Publication: St. Louis, Mo. : [s.n., 1896-
مواضيع طبية MeSH: Semicircular Canal Dehiscence*/surgery, Humans ; Female ; Male ; Middle Aged ; Sex Factors ; Age Factors ; Treatment Outcome ; Adult ; Retrospective Studies ; Aged ; Otologic Surgical Procedures/methods ; Otologic Surgical Procedures/adverse effects ; Cohort Studies
مستخلص: Objective: To investigate the independent and interactive effects of patient age and sex on superior canal dehiscence (SCD) repair outcomes.
Methods: This was a cohort study of consecutive SCD repairs via the middle fossa approach at an institution between 2011 and 2022. We constructed multivariable regression models assessing surgical outcomes with age and sex as the primary predictors. Models controlled for surgery duration, follow-up duration, and relevant surgical and medical history. Subsequently, we repeated each model with the incorporation of an interaction term between patient age and sex.
Results: Among 402 repairs, average age was 50 years, and 63% of cases were females. There was a significant interaction between patient age and sex with respect to symptom resolution score (SRS) (adj. β 0.80, 95% C.I. 0.04-1.56). Older age was associated with lower SRS among females (-0.84, -1.29 to -0.39 point per year) but not significantly associated with SRS among males (0.04, -0.65 to 0.56 point per year). Furthermore, older age independently predicted a greater magnitude of increase in air conduction at 8000 Hz following surgery regardless of sex (adj. β 2.1, 0.2-4.0 dB per 10-year increase).
Conclusions: This is the first study on the interactive effect between patient age and sex with respect to SCD repair outcomes. Older age predicted poorer symptomatic response among female patients but did not predict symptomatic response among male patients. Furthermore, older age predicted more severe high-frequency hearing loss following SCD repairs among both female and male patients.
Level of Evidence: 3 Laryngoscope, 134:3363-3370, 2024.
(© 2024 The American Laryngological, Rhinological and Otological Society, Inc.)
References: Eberhard KE, Chari DA, Nakajima HH, Klokker M, Cayé‐Thomasen P, Lee DJ. Current trends, controversies, and future directions in the evaluation and management of superior canal dehiscence syndrome. Front Neurol. 2021;12:638574.
Ward BK, Carey JP, Minor LB. Superior canal dehiscence syndrome: lessons from the first 20 years. Front Neurol. 2017;8:177.
Carey JP, Minor LB, Nager GT. Dehiscence or thinning of bone overlying the superior semicircular canal in a temporal bone survey. Arch Otolaryngol Head Neck Surg. 2000;126(2):137‐147.
Niesten MEF, Lookabaugh S, Curtin H, et al. Familial superior canal dehiscence syndrome. JAMA Otolaryngol Head Neck Surg. 2014;140(4):363‐368.
Jackson NM, Allen LM, Morell B, et al. The relationship of age and radiographic incidence of superior semicircular canal dehiscence in pediatric patients. Otol Neurotol. 2015;36(1):99‐105.
Nguyen T, Sheppard JP, Duong C, et al. Age and gender considerations on the symptomology in patients with superior semicircular canal dehiscence: a systematic review and case illustration. J Clin Neurosci. 2019;65:112‐120.
Kulinich DP, Kjos A, Anderson R, et al. Assessment of metabolic markers and osteoporosis in 250 patients with superior semicircular canal dehiscence treated with middle fossa craniotomy. World Neurosurg. 2022;166:e52‐e59.
Yu A, Teich DL, Moonis G, Wong ET. Superior semicircular canal dehiscence in East Asian women with osteoporosis. BMC Ear Nose Throat Disord. 2012;12:8.
Nadgir RN, Ozonoff A, Devaiah AK, Halderman AA, Sakai O. Superior semicircular canal dehiscence: congenital or acquired condition? AJNR Am J Neuroradiol. 2011;32(5):947‐949.
Yang HH, Lum M, Kaur T, Yang I, Gopen QS. Postoperative Pneumolabyrinth following the middle cranial fossa approach for superior Semicircular Canal dehiscence repair, 2014–2020. Otolaryngol Head Neck Surg. 2023;168(3):453‐461.
Crovetto MA, Whyte J, Rodriguez OM, et al. Influence of aging and menopause in the origin of the superior semicircular canal dehiscence. Otol Neurotol. 2012;33(4):681‐684.
Davvaz B, Hasani M, Haghnegahdar A. Evaluation of superior Semicircular Canal morphology and its relationship with glenoid fossa roof thickness using cone beam computed tomography. Radiol Res Pract. 2022;2022:1565038 7.
Ward BK, van de Berg R, van Rompaey V, et al. Superior semicircular canal dehiscence syndrome: diagnostic criteria consensus document of the committee for the classification of vestibular disorders of the Bárány society. J Vestib Res. 2021;31(3):131‐141.
Yang HH, Yang I, Gopen QS. Audiometric outcomes after the middle cranial fossa repair of superior Semicircular Canal dehiscence. Otol Neurotol. 2023;44(6):593‐599.
Yang HH, Patel VS, Yang I, Gopen QS. Low‐lying tegmen and surgical outcomes following the middle cranial fossa repair of superior canal dehiscence. Otolaryngol Head Neck Surg. 2023;170:195‐203. https://doi.org/10.1002/ohn.480.
Ellsperman SE, Telian SA, Kileny PR, Welch CM. Auditory outcomes following transmastoid and middle cranial fossa approaches for superior semicircular canal dehiscence repair. Otol Neurotol. 2021;42(10):1544‐1552.
Ward BK, Agrawal Y, Nguyen E, et al. Hearing outcomes after surgical plugging of the superior semicircular canal by a middle cranial fossa approach. Otol Neurotol. 2012;33(8):1386‐1391.
Yang HH, Patel VS, Yang I, Gopen QS. Computed tomography approximated superior semicircular canal dehiscence size and location and their association with clinical presentation. J Clin Neurosci. 2023;112:30‐37.
Equilibrium C on H and. Committee on hearing and equilibrium guidelines for the evaluation of results of treatment of conductive hearing loss*. Otolaryngol Head Neck Surg. 1995;113(3):186‐187.
Paplou V, Schubert NMA, Pyott SJ. Age‐related changes in the cochlea and vestibule: shared patterns and processes. Front Neurosci. 2021;15:680856.
Parthasarathy A, Romero Pinto S, Lewis RM, Goedicke W, Polley DB. Data‐driven segmentation of audiometric phenotypes across a large clinical cohort. Sci Rep. 2020;10(1):6704.
Maes L, Dhooge I, D'Haenens W, et al. The effect of age on the sinusoidal harmonic acceleration test, pseudorandom rotation test, velocity step test, caloric test, and vestibular‐evoked myogenic potential test. Ear Hear. 2010;31(1):84‐94.
Zapala DA, Olsholt KF, Lundy LB. A comparison of water and air caloric responses and their ability to distinguish between patients with normal and impaired ears. Ear Hear. 2008;29(4):585‐600.
Ji L, Zhai S. Aging and the peripheral vestibular system. J Otolaryngol. 2018;13(4):138‐140.
Davey S, Kelly‐Morland C, Phillips JS, Nunney I, Pawaroo D. Assessment of superior semicircular canal thickness with advancing age. Laryngoscope. 2015;125(8):1940‐1945.
Klopp‐Dutote N, Kolski C, Biet A, Strunski V, Page C. A radiologic and anatomic study of the superior semicircular canal. Eur Ann Otorhinolaryngol Head Neck Dis. 2016;133(2):91‐94.
Pietschmann P, Rauner M, Sipos W, Kerschan‐Schindl K. Osteoporosis: an age‐related and gender‐specific disease—a mini‐review. Gerontology. 2009;55(1):3‐12.
Barbara M, Margani V, Voltattorni A, Monini S, Covelli E. Concomitant Dehiscences of the temporal bone: a case‐based study. Ear Nose Throat J. 2022;101(8):NP324‐NP328.
Formeister EJ, Zhang L, Dent J, Aygun N, Carey JP. Predictive factors for concurrent tegmen dehiscence in superior canal dehiscence syndrome. Otol Neurotol. 2022;43(4):494‐499.
Merchant SN, Nadol JB, Schuknecht HF. In: Shelton CT, ed. Schuknecht's Pathology of the Ear. 3rd ed. People's Medical Pub; 2010.
Ikeda R, Nakaya K, Oshima H, Oshima T, Kawase T, Kobayashi T. Effect of aspiration of perilymph during stapes surgery on the endocochlear potential of Guinea pig. Otolaryngol Head Neck Surg. 2011;145(5):801‐805.
Agrawal Y, Migliaccio AA, Minor LB, Carey JP. Vestibular hypofunction in the initial postoperative period after surgical treatment of superior semicircular canal dehiscence. Otol Neurotol. 2009;30(4):502‐506.
فهرسة مساهمة: Keywords: age; middle cranial fossa approach; sex; superior canal dehiscence
تواريخ الأحداث: Date Created: 20240221 Date Completed: 20240617 Latest Revision: 20240617
رمز التحديث: 20240617
DOI: 10.1002/lary.31356
PMID: 38381092
قاعدة البيانات: MEDLINE
الوصف
تدمد:1531-4995
DOI:10.1002/lary.31356