دورية أكاديمية
أعرض في EDS

Possible Correlations between Mean Platelet Volume and Biological, Electrocardiographic, and Echocardiographic Parameters in Patients with Heart Failure.

التفاصيل البيبلوغرافية
العنوان: Possible Correlations between Mean Platelet Volume and Biological, Electrocardiographic, and Echocardiographic Parameters in Patients with Heart Failure.
المؤلفون: Catană A; Department of Cardiology, University of Medicine and Pharmacy 'Carol Davila', Emergency Hospital 'Bagdasar-Arseni', 020021 Bucharest, Romania., Andrei CL; Department of Cardiology, University of Medicine and Pharmacy 'Carol Davila', Emergency Hospital 'Bagdasar-Arseni', 020021 Bucharest, Romania., Guberna S; Department of Cardiology, University of Medicine and Pharmacy 'Carol Davila', Emergency Hospital 'Bagdasar-Arseni', 020021 Bucharest, Romania., Ceban O; Economic Cybernetics and Informatics Department, The Bucharest University of Economic Studies, 010552 Bucharest, Romania., Sinescu CJ; Department of Cardiology, University of Medicine and Pharmacy 'Carol Davila', Emergency Hospital 'Bagdasar-Arseni', 020021 Bucharest, Romania.
المصدر: Life (Basel, Switzerland) [Life (Basel)] 2024 Feb 16; Vol. 14 (2). Date of Electronic Publication: 2024 Feb 16.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101580444 Publication Model: Electronic Cited Medium: Print ISSN: 2075-1729 (Print) Linking ISSN: 20751729 NLM ISO Abbreviation: Life (Basel) Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI AG, 2011-
مستخلص: (1) Background: Despite advancements in medical research and discoveries, heart failure (HF) still represents a significant and prevalent public health challenge. It is characterized by persistently high mortality and morbidity rates, along with increased rates of readmissions, particularly among the elderly population. (2) Methods: This study was conducted retrospectively on 260 patients with stable or decompensated chronic HF. The parameter of interest in the study population was the mean platelet volume (MPV), and the main objective of the research was to identify a possible relationship between MPV and several variables-biological (NT-proBNP, presepsin, red cell distribution width (RDW)), electrocardiographic (atrial fibrillation (AFib) rhythm, sinus rhythm (SR)), and echocardiographic (left ventricle ejection fraction (LVEF), left atrial (LA) diameter, left ventricle (LV) diameter, pulmonary hypertension (PH)). (3) Results: By applying logistic and linear regression models, we assessed whether there is a correlation between MPV and biological, electrocardiographic, and echocardiographic variables in patients with HF. The results revealed linear relationships between MPV and NT pro-BNP values and between MPV and RDW values, and an increased probability for the patients to have an AFib rhythm, reduced LVEF, dilated LA, dilated LV, and PH as their MPV value increases. The results were deemed statistically relevant based on a p -value below 0.05. (4) Conclusions: Through regression model analyses, our research revealed that certain negative variables in HF patients such as increased levels of NT-proBNP, increased levels of RDW, AFib rhythm, reduced LVEF, dilated LA, dilated LV, and PH, could be predicted based on MPV values.
References: Arterioscler Thromb Vasc Biol. 2011 May;31(5):1215-8. (PMID: 21330610)
Blood Coagul Fibrinolysis. 2008 Jul;19(5):411-4. (PMID: 18600091)
Platelets. 2016 Nov;27(7):607-612. (PMID: 27686008)
Stroke. 2004 Jul;35(7):1688-91. (PMID: 15143290)
J Clin Pathol. 1983 Jun;36(6):693-6. (PMID: 6343437)
Angiology. 2014 Jul;65(6):533-7. (PMID: 23671213)
Thromb Res. 2007;120(5):709-13. (PMID: 17287016)
Platelets. 2013;24(6):493-7. (PMID: 22994845)
PLoS One. 2014 Aug 18;9(8):e104861. (PMID: 25133510)
J Thromb Haemost. 2010 Jan;8(1):148-56. (PMID: 19691485)
Eur J Heart Fail. 2002 Aug;4(4):461-7. (PMID: 12167384)
Eur Heart J. 2021 Dec 21;42(48):4901. (PMID: 34649282)
Eur Heart J. 1993 Feb;14(2):205-12. (PMID: 8449196)
J Clin Med. 2022 Mar 31;11(7):. (PMID: 35407558)
Platelets. 2023 Dec;34(1):2188965. (PMID: 37157842)
Circulation. 1998 Mar 31;97(12):1136-43. (PMID: 9537339)
Biochem Med (Zagreb). 2015;25(1):97-102. (PMID: 25672473)
Eur J Heart Fail. 1999 Aug;1(3):243-9. (PMID: 10935670)
Acta Cardiol Sin. 2017 May;33(3):292-300. (PMID: 28559660)
BMC Cardiovasc Disord. 2015 Jun 16;15:52. (PMID: 26077978)
Thromb Res. 1983 Dec 1;32(5):443-60. (PMID: 6658722)
فهرسة مساهمة: Keywords: NT-proBNP; atrial fibrillation; heart failure; left ventricular ejection fraction; mean platelet volume
تواريخ الأحداث: Date Created: 20240224 Latest Revision: 20240227
رمز التحديث: 20240227
مُعرف محوري في PubMed: PMC10890115
DOI: 10.3390/life14020260
PMID: 38398768
قاعدة البيانات: MEDLINE
الوصف
تدمد:2075-1729
DOI:10.3390/life14020260