دورية أكاديمية

The role of echocardiographic assessment for the risk of adverse events in liver transplant recipients: A systematic review and meta-analysis.

التفاصيل البيبلوغرافية
العنوان: The role of echocardiographic assessment for the risk of adverse events in liver transplant recipients: A systematic review and meta-analysis.
المؤلفون: Lai Q; General Surgery and Organ Transplantation Unit, Sapienza University of Rome, AOU Policlinico Umberto I, Rome, Italy. Electronic address: quirino.lai@uniroma1.it., Caimano M; Department of Medical and Surgical Sciences, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy., Canale F; General Surgery and Organ Transplantation Unit, Sapienza University of Rome, AOU Policlinico Umberto I, Rome, Italy., Birtolo LI; Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, AOU Policlinico Umberto I, Rome, Italy., Ferri F; Department of Translational and Precision Medicine, Sapienza University of Rome, AOU Umberto I Policlinico of Rome, Rome, Italy., Corradini SG; Department of Translational and Precision Medicine, Sapienza University of Rome, AOU Umberto I Policlinico of Rome, Rome, Italy., Mancone M; Department of Clinical, Internal, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, AOU Policlinico Umberto I, Rome, Italy., Marrone G; Department of Translational Medicine and Surgery, Catholic University of Sacred Heart, Rome, Italy., Pedicino D; Department of Cardiovascular Medicine, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy., Rossi M; General Surgery and Organ Transplantation Unit, Sapienza University of Rome, AOU Policlinico Umberto I, Rome, Italy., Vernole E; Department of Translational Medicine and Surgery, Catholic University of Sacred Heart, Rome, Italy., Pompili M; Department of Translational Medicine and Surgery, Catholic University of Sacred Heart, Rome, Italy., Biolato M; Department of Translational Medicine and Surgery, Catholic University of Sacred Heart, Rome, Italy.
المصدر: Transplantation reviews (Orlando, Fla.) [Transplant Rev (Orlando)] 2024 Apr; Vol. 38 (2), pp. 100838. Date of Electronic Publication: 2024 Feb 22.
نوع المنشور: Meta-Analysis; Systematic Review; Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: W.B. Saunders Country of Publication: United States NLM ID: 8804364 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-9816 (Electronic) Linking ISSN: 0955470X NLM ISO Abbreviation: Transplant Rev (Orlando) Subsets: In Process
أسماء مطبوعة: Publication: Philadelphia Pa : W.B. Saunders
Original Publication: Orlando : Grune & Stratton, c1987-
مستخلص: Background & Aims: Echocardiographic findings may provide valuable information about the cardiac conditions in cirrhotic patients waiting for liver transplantation (LT). However, data on the ability of the different echocardiographic parameters to predict post-transplant risk of mortality are scarce and heterogeneous. This systematic review evaluates the role of different echocardiographic features as predictors of post-LT mortality. A meta-analysis was also performed according to the observed results.
Methods: A systematic review was conducted according to PRISMA guidelines. Medline (PubMed) database was searched through February 2023 for relevant published original articles reporting the prognostic value of echocardiographic findings associated with outcomes of adult LT recipients. The risk of bias in included articles was assessed using ROBINS-E tool. Methodological quality varied from low to high across the risk of bias domains.
Results: Twenty-three studies were identified after the selection process; ten were enrollable for the meta-analyses. According to the results observed, the E/A ratio fashioned as a continuous value (HR = 0.43, 95%CI = 0.25-0.76; P = 0.003), and tricuspid regurgitation (HR = 2.36, 95%CI = 1.05-5.31; P = 0.04) were relevant predicting variables for post-LT death. Other echocardiographic findings failed to merge with statistical relevance.
Conclusion: Tricuspid regurgitation and left ventricular diastolic dysfunction play a role in the prediction of post-LT death. More studies are needed to clarify further the impact of these echocardiographic features in the transplantation setting.
Competing Interests: Declaration of Competing Interest None.
(Copyright © 2024 Elsevier Inc. All rights reserved.)
فهرسة مساهمة: Keywords: E/A ratio; E/e’; Left ventricular diastolic dysfunction; Left ventricular ejection fraction; Tricuspid regurgitation
تواريخ الأحداث: Date Created: 20240228 Latest Revision: 20240807
رمز التحديث: 20240807
DOI: 10.1016/j.trre.2024.100838
PMID: 38417399
قاعدة البيانات: MEDLINE
الوصف
تدمد:1557-9816
DOI:10.1016/j.trre.2024.100838