Pancytopenia following adjuvant therapy with interferon-gamma in a patient with disseminated nocardiosis.

التفاصيل البيبلوغرافية
العنوان: Pancytopenia following adjuvant therapy with interferon-gamma in a patient with disseminated nocardiosis.
المؤلفون: Derungs T; Department of Gastroenterology, Infectious Disease and Rheumatology, Charité Universitätsmedizin Berlin, Germany. Electronic address: thomas.derungs@charite.de., Poddubnyy D; Department of Gastroenterology, Infectious Disease and Rheumatology, Charité Universitätsmedizin Berlin, Germany., Schneider T; Department of Gastroenterology, Infectious Disease and Rheumatology, Charité Universitätsmedizin Berlin, Germany.
المصدر: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases [Int J Infect Dis] 2024 May; Vol. 142, pp. 106997. Date of Electronic Publication: 2024 Mar 06.
نوع المنشور: Case Reports
اللغة: English
بيانات الدورية: Publisher: Elsevier Country of Publication: Canada NLM ID: 9610933 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-3511 (Electronic) Linking ISSN: 12019712 NLM ISO Abbreviation: Int J Infect Dis Subsets: MEDLINE
أسماء مطبوعة: Publication: Hamilton, ON : Elsevier
Original Publication: Hamilton, ON : Decker, c1996-
مواضيع طبية MeSH: Pancytopenia*/etiology , Nocardia Infections*/diagnosis , Nocardia Infections*/drug therapy, Humans ; Interferon-gamma ; Recombinant Proteins/therapeutic use
مستخلص: A patient with disseminated nocardiosis developed pancytopenia after treatment with recombinant interferon-gamma (IFN-γ). While no previous clinical reports link pancytopenia to IFN-γ, our observations align with basic research on myelosuppressive effects of IFN-γ. Adjunctive IFN-γ may improve standard nocardiosis therapy, but vigilant monitoring of its hematologic effects is necessary.
Competing Interests: Declarations of competing interest All authors declare to have no conflict of interest.
(Copyright © 2024. Published by Elsevier Ltd.)
فهرسة مساهمة: Keywords: Interferon gamma; Nocardiosis; Pancytopenia
المشرفين على المادة: 82115-62-6 (Interferon-gamma)
0 (Recombinant Proteins)
تواريخ الأحداث: Date Created: 20240308 Date Completed: 20240416 Latest Revision: 20240416
رمز التحديث: 20240416
DOI: 10.1016/j.ijid.2024.106997
PMID: 38458424
قاعدة البيانات: MEDLINE
الوصف
تدمد:1878-3511
DOI:10.1016/j.ijid.2024.106997