دورية أكاديمية
Chromones from the endophytic fungus Bipolaris eleusines.
العنوان: | Chromones from the endophytic fungus Bipolaris eleusines. |
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المؤلفون: | Fan YZ; School of Pharmaceutical Sciences, South-Central Minzu University, Wuhan, 430074, People's Republic of China., Tian C; School of Pharmaceutical Sciences, South-Central Minzu University, Wuhan, 430074, People's Republic of China., Tong SY; School of Pharmaceutical Sciences, South-Central Minzu University, Wuhan, 430074, People's Republic of China., Liu Q; School of Pharmaceutical Sciences, South-Central Minzu University, Wuhan, 430074, People's Republic of China., Xu F; School of Pharmaceutical Sciences, South-Central Minzu University, Wuhan, 430074, People's Republic of China., Shi BB; School of Pharmaceutical Sciences, South-Central Minzu University, Wuhan, 430074, People's Republic of China. Electronic address: shibb0505@163.com., Ai HL; School of Pharmaceutical Sciences, South-Central Minzu University, Wuhan, 430074, People's Republic of China. Electronic address: aihonglian@mail.scuec.edu.cn., Liu JK; School of Pharmaceutical Sciences, South-Central Minzu University, Wuhan, 430074, People's Republic of China. Electronic address: liujikai@mail.scuec.edu.cn. |
المصدر: | Phytochemistry [Phytochemistry] 2024 May; Vol. 221, pp. 114046. Date of Electronic Publication: 2024 Mar 07. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Elsevier Country of Publication: England NLM ID: 0151434 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3700 (Electronic) Linking ISSN: 00319422 NLM ISO Abbreviation: Phytochemistry Subsets: MEDLINE |
أسماء مطبوعة: | Publication: 2003- : London : Elsevier Original Publication: 1961-2003: Oxford : Pergamon Press. |
مواضيع طبية MeSH: | Chromones*/pharmacology , Chromones*/chemistry , Ascomycota*/chemistry, Molecular Structure ; Bipolaris |
مستخلص: | Eight previously undescribed chromones eleusineketones A-H (1-8), as well as eight known compounds (9-16), were isolated from the endophytic fungus Bipolaris eleusines. These planar structures were created using an in-depth analysis of their spectral data, which included 1D, 2D, and HRESIMS data. Furthermore, the absolute configurations of compounds 1, 2, and 6 were determined by spectroscopic analysis and quantum chemical computational approaches, and compound 5 was determined by single-crystal X-ray diffraction analysis. The cytotoxic activity assay revealed that compounds 1 and 5 both inhibited MDA-MB-231 cells with IC Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (Copyright © 2024 Elsevier Ltd. All rights reserved.) |
فهرسة مساهمة: | Keywords: Absolute configurations; Bipolaris eleusines; Chromones; Cytotoxic activity; Endophytic fungus |
المشرفين على المادة: | 0 (Chromones) |
SCR Organism: | Bipolaris eleusines |
تواريخ الأحداث: | Date Created: 20240309 Date Completed: 20240408 Latest Revision: 20240408 |
رمز التحديث: | 20240408 |
DOI: | 10.1016/j.phytochem.2024.114046 |
PMID: | 38460780 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1873-3700 |
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DOI: | 10.1016/j.phytochem.2024.114046 |