دورية أكاديمية
Identification of an SCF Ubiquitin Ligase Complex that Contributes to Resistance Against Valsa Canker in Apple.
| العنوان: | Identification of an SCF Ubiquitin Ligase Complex that Contributes to Resistance Against Valsa Canker in Apple. |
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| المؤلفون: | Han P; State Key Laboratory for Crop Stress Resistance and High-Efficiency Production, College of Plant Protection, Northwest A&F University, Yangling, Shaanxi 712100, China., Zhang R; State Key Laboratory for Crop Stress Resistance and High-Efficiency Production, College of Plant Protection, Northwest A&F University, Yangling, Shaanxi 712100, China., Li R; State Key Laboratory for Crop Stress Resistance and High-Efficiency Production, College of Plant Protection, Northwest A&F University, Yangling, Shaanxi 712100, China., Li F; State Key Laboratory for Crop Stress Resistance and High-Efficiency Production, College of Plant Protection, Northwest A&F University, Yangling, Shaanxi 712100, China., Huang L; State Key Laboratory for Crop Stress Resistance and High-Efficiency Production, College of Plant Protection, Northwest A&F University, Yangling, Shaanxi 712100, China. |
| المصدر: | Molecular plant-microbe interactions : MPMI [Mol Plant Microbe Interact] 2024 Jun; Vol. 37 (6), pp. 520-529. Date of Electronic Publication: 2024 Jun 17. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: APS Press Country of Publication: United States NLM ID: 9107902 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0894-0282 (Print) Linking ISSN: 08940282 NLM ISO Abbreviation: Mol Plant Microbe Interact Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: St. Paul, MN : APS Press, [c1987- |
| مواضيع طبية MeSH: | Malus*/microbiology , Malus*/genetics , Malus*/immunology , Plant Diseases*/microbiology , Plant Diseases*/immunology , Disease Resistance*/genetics , SKP Cullin F-Box Protein Ligases*/metabolism , SKP Cullin F-Box Protein Ligases*/genetics , Plant Proteins*/genetics , Plant Proteins*/metabolism , Ascomycota*/physiology, Gene Expression Regulation, Plant ; F-Box Proteins/metabolism ; F-Box Proteins/genetics ; Plants, Genetically Modified |
| مستخلص: | E3 ubiquitin ligases play a critical role in plant disease resistance. Among them, the Skp1-Cullin-F-box protein (SCF) ubiquitin ligase complex is the largest family and regulates the ubiquitination of a wide range of proteins. Apple Valsa canker (AVC) is a fungal disease of apple trees caused by the fungus Valsa mali , which can lead to significant economic losses. However, the function of the SCF complex in apple resistance to this disease is still largely unknown. In this study, we identified an SCF ubiquitin ligase complex that can enhance resistance to Valsa canker in apple. Disease evaluation experiments demonstrated that MdSkp1 increased apple resistance to AVC. Furthermore, MdSkp1 interacted with an F-box protein, MdSKIP14, and interacted with a cullin-1 protein, MdCUL1, to form an SCF ubiquitin ligase complex. Additionally, we revealed both MdSKIP14 and MdCUL1 as positive regulators of AVC resistance. In conclusion, our results identified an SCF complex capable of contributing to apple resistance against AVC, providing a theoretical basis for apple disease resistance and the sustainable development of the industry. [Formula: see text] Copyright © 2024 The Author(s). This is an open access article distributed under the CC BY-NC-ND 4.0 International license. Competing Interests: The author(s) declare no conflict of interest. |
| فهرسة مساهمة: | Keywords: E3 ubiquitin ligases; Malus × domestica; genetic transformation; protein interactions |
| المشرفين على المادة: | EC 2.3.2.27 (SKP Cullin F-Box Protein Ligases) 0 (Plant Proteins) 0 (F-Box Proteins) |
| تواريخ الأحداث: | Date Created: 20240312 Date Completed: 20240627 Latest Revision: 20240627 |
| رمز التحديث: | 20240627 |
| DOI: | 10.1094/MPMI-12-23-0206-R |
| PMID: | 38470518 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 0894-0282 |
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| DOI: | 10.1094/MPMI-12-23-0206-R |