دورية أكاديمية
Pediatric cutaneous mucormicosis.
| العنوان: | Pediatric cutaneous mucormicosis. |
|---|---|
| المؤلفون: | Matei MC; Department of Dermatology, Hospital Miguel Servet, Zaragoza, Spain. marimatei.96@gmail.com., Ramirez SC, Sanz SS, Cazana TG, Gomez CL, Arnau NM, Alonso MB, Alonso IB |
| المصدر: | Dermatology online journal [Dermatol Online J] 2023 Dec 15; Vol. 29 (6). Date of Electronic Publication: 2023 Dec 15. |
| نوع المنشور: | Case Reports; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: University of California, Davis Country of Publication: United States NLM ID: 9610776 Publication Model: Electronic Cited Medium: Internet ISSN: 1087-2108 (Electronic) Linking ISSN: 10872108 NLM ISO Abbreviation: Dermatol Online J Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: [Davis, Calif.] : University of California, Davis, c1995- |
| مواضيع طبية MeSH: | Amphotericin B*/therapeutic use , Mucormycosis*/diagnosis , Mucormycosis*/therapy, Male ; Humans ; Child ; Rhizopus ; Skin/pathology ; Necrosis/complications ; Antifungal Agents/therapeutic use |
| مستخلص: | A 9-year-old boy diagnosed with acute myeloblastic leukemia and undergoing chemotherapy, was admitted with febrile neutropenia. During his admission, several violaceous plaques appeared on the upper extremities and anterior left hemithorax, which worsened and acquired a necrotic center. We performed a biopsy and histology showed a cutaneous infarction at the dermoepidermal and subcutaneous level. We observed abundant wide hyphae with right-angled branching and a culture isolated Rhizopus oryzae. A plastic surgery consultant performed a surgical debridement of the lesions and treatment was started with intravenous amphotericin B. The patient did well on treatment and after almost a month of hospitalization, he was discharged with oral posaconazole. Mucormycosis is an opportunistic fungal infection associated with immunosuppression, particularly involving prematurity and hematological diseases in the pediatric age group. Multiple lesions, as in our case, are infrequent. The clinical presentation is variable. Direct smear or histological observation is the quickest diagnostic technique whereas culture is the most definitive. The combination of surgical debridement and amphotericin B is the treatment with the highest survival rates. |
| المشرفين على المادة: | 7XU7A7DROE (Amphotericin B) 0 (Antifungal Agents) |
| تواريخ الأحداث: | Date Created: 20240313 Date Completed: 20240315 Latest Revision: 20240315 |
| رمز التحديث: | 20240315 |
| DOI: | 10.5070/D329662994 |
| PMID: | 38478665 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1087-2108 |
|---|---|
| DOI: | 10.5070/D329662994 |