دورية أكاديمية
أعرض في EDS

Evaluating the association between opium abuse, blood lead levels, and the complexity of coronary artery disease.

التفاصيل البيبلوغرافية
العنوان: Evaluating the association between opium abuse, blood lead levels, and the complexity of coronary artery disease.
المؤلفون: Khameneh Bagheri R; Department of Cardiovascular Diseases, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran., Mousavi SH; Medical Toxicology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran., Mehrad-Majd H; Clinical Research Development Unit, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran., Jamili MJ; Department of Cardiovascular Diseases, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran., Nasimi Shad A; Student Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran., Baradaran Rahimi V; Department of Cardiovascular Diseases, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.; Pharmacological Research Center of Medicinal Plants, Mashhad University of Medical Sciences, Mashhad, Iran.
المصدر: Physiological reports [Physiol Rep] 2024 Mar; Vol. 12 (5), pp. e15975.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: published by Wiley Periodicals, Inc. on behalf of the American Physiological Society and The Physiological Society Country of Publication: United States NLM ID: 101607800 Publication Model: Print Cited Medium: Internet ISSN: 2051-817X (Electronic) Linking ISSN: 2051817X NLM ISO Abbreviation: Physiol Rep Subsets: MEDLINE
أسماء مطبوعة: Original Publication: [Malden MA] : published by Wiley Periodicals, Inc. on behalf of the American Physiological Society and The Physiological Society, 2013-
مواضيع طبية MeSH: Coronary Artery Disease*/diagnostic imaging , Coronary Artery Disease*/epidemiology , Coronary Artery Disease*/etiology , Percutaneous Coronary Intervention* , Opium Dependence*/complications , Opium Dependence*/epidemiology, Humans ; Lead/adverse effects ; Opium/adverse effects ; Severity of Illness Index
مستخلص: Opium abuse and exposure to heavy metals elevate the risk of coronary artery disease (CAD). Therefore, we aimed to determine the association between opium abuse and blood lead levels (BLLs) and the CAD complexity. We evaluated patients with acute coronary symptoms who underwent coronary angiography, and those with >50% stenosis in at least one of the coronary arteries were included. Furthermore, Synergy between PCI with Taxus and Cardiac Surgery I (SYNTAX I) score and BLLs were measured. Based on the opium abuse, 95 patients were subdivided into opium (45) and control (50) groups. Differences in demographics and CAD risk factors were insignificant between the two groups. The median BLLs were remarkably higher in the opium group than in controls (36 (35.7) and 20.5 μg/dL (11.45), respectively, p = 0.003). We also revealed no significant differences in SYNTAX score between the two groups (15.0 (9.0) and 17.5 (14.0), respectively, p = 0.28). Additionally, we found no significant correlation between BLLs and the SYNTAX scores (p = 0.277 and r = -0.113). Opium abuse was associated with high BLLs. Neither opium abuse nor high BLLs were correlated with the complexity of CAD. Further studies are warranted to establish better the relationship between opium abuse, BLLs, and CAD.
(© 2024 The Authors. Physiological Reports published by Wiley Periodicals LLC on behalf of The Physiological Society and the American Physiological Society.)
References: J Geriatr Cardiol. 2021 Nov 28;18(11):857-866. (PMID: 34908923)
Daru. 2018 Sep;26(1):77-83. (PMID: 30159760)
Int J Environ Res Public Health. 2020 Mar 23;17(6):. (PMID: 32210108)
Heart. 2014 Feb;100(4):276-87. (PMID: 23878176)
Am J Cardiol. 2004 May 15;93(10):1295-7. (PMID: 15135709)
Sci Rep. 2019 Nov 5;9(1):15995. (PMID: 31690775)
Postgrad Med. 2010 Nov;122(6):87-97. (PMID: 21084785)
Br J Pharmacol. 2015 Apr;172(8):2026-50. (PMID: 25521834)
Int J Prev Med. 2010 Summer;1(3):182-6. (PMID: 21566789)
Nat Rev Cardiol. 2013 Dec;10(12):733-40. (PMID: 24145895)
Eur J Pharmacol. 2018 Jun 5;828:1-8. (PMID: 29559303)
Int J Mol Sci. 2021 Mar 03;22(5):. (PMID: 33802308)
Cancer Epidemiol Biomarkers Prev. 2004 Jun;13(6):1068-70. (PMID: 15184266)
Pain Med. 2016 Mar;17(3):444-455. (PMID: 26361245)
J Res Med Sci. 2010 Jan;15(1):27-32. (PMID: 21526055)
Arch Iran Med. 2016 Dec;19(12):870-876. (PMID: 27998163)
Physiol Rep. 2022 Nov;10(22):e15513. (PMID: 36394077)
Physiol Rep. 2024 Mar;12(5):e15975. (PMID: 38480374)
Addict Health. 2021 Apr;13(2):77-84. (PMID: 34703528)
PLoS One. 2023 Apr 19;18(4):e0283707. (PMID: 37074987)
Nat Rev Nephrol. 2022 Feb;18(2):113-128. (PMID: 34621058)
Biofactors. 2022 Jul;48(4):857-882. (PMID: 35648433)
Heart Views. 2014 Oct-Dec;15(4):99-105. (PMID: 25774251)
Environ Health Perspect. 2021 Feb;129(2):27006. (PMID: 33621129)
Lancet Public Health. 2018 Apr;3(4):e177-e184. (PMID: 29544878)
Noncoding RNA. 2018 Sep 17;4(3):. (PMID: 30227648)
Front Chem. 2020 Aug 27;8:737. (PMID: 33195013)
J Res Med Sci. 2012 Oct;17(10):958-61. (PMID: 23825997)
Environ Sci Pollut Res Int. 2017 Oct;24(28):22275-22283. (PMID: 28799038)
Int J Drug Policy. 2022 Jun;104:103695. (PMID: 35472727)
Chemosphere. 2017 Aug;180:540-544. (PMID: 28431391)
Subst Abuse Treat Prev Policy. 2017 Oct 5;12(1):43. (PMID: 28982369)
Am Soc Clin Oncol Educ Book. 2015;:e593-9. (PMID: 25993228)
Int J Environ Res Public Health. 2019 Jul 18;16(14):. (PMID: 31323774)
Inflammopharmacology. 2021 Oct;29(5):1379-1387. (PMID: 34420187)
Nat Rev Cardiol. 2014 May;11(5):276-89. (PMID: 24663092)
معلومات مُعتمدة: 980721 Mashhad University of Medical Sciences (MUMS)
فهرسة مساهمة: Keywords: SYNTAX I score; blood lead level; coronary artery disease; opium
المشرفين على المادة: 2P299V784P (Lead)
8008-60-4 (Opium)
تواريخ الأحداث: Date Created: 20240313 Date Completed: 20240315 Latest Revision: 20240316
رمز التحديث: 20240316
مُعرف محوري في PubMed: PMC10937294
DOI: 10.14814/phy2.15975
PMID: 38480374
قاعدة البيانات: MEDLINE
الوصف
تدمد:2051-817X
DOI:10.14814/phy2.15975