دورية أكاديمية
أعرض في EDS

Efficacy of isobutylamido thiazolyl resorcinol for prevention of laser-induced post-inflammatory hyperpigmentation: A randomized, controlled trial.

التفاصيل البيبلوغرافية
العنوان: Efficacy of isobutylamido thiazolyl resorcinol for prevention of laser-induced post-inflammatory hyperpigmentation: A randomized, controlled trial.
المؤلفون: Vachiramon V; Division of Dermatology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand., Sakpuwadol N; Division of Dermatology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand., Yongpisarn T; Division of Dermatology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand., Anuntrangsee T; Division of Dermatology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand., Palakornkitti P; Division of Dermatology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
المصدر: Journal of cosmetic dermatology [J Cosmet Dermatol] 2024 Jul; Vol. 23 (7), pp. 2450-2457. Date of Electronic Publication: 2024 Mar 18.
نوع المنشور: Journal Article; Randomized Controlled Trial
اللغة: English
بيانات الدورية: Publisher: Blackwell Science Country of Publication: England NLM ID: 101130964 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1473-2165 (Electronic) Linking ISSN: 14732130 NLM ISO Abbreviation: J Cosmet Dermatol Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Oxford, UK : Blackwell Science, c2002-
مواضيع طبية MeSH: Resorcinols*/administration & dosage , Resorcinols*/adverse effects , Resorcinols*/therapeutic use , Hyperpigmentation*/prevention & control , Hyperpigmentation*/etiology , Lasers, Solid-State*/therapeutic use , Lentigo*/etiology , Lentigo*/prevention & control , Lentigo*/therapy, Humans ; Female ; Adult ; Middle Aged ; Male ; Treatment Outcome ; Single-Blind Method
مستخلص: Background: Q-switched (QS) Nd: YAG laser is one of the treatment options for solar lentigines (SLs). However, the incidence of post-inflammatory hyperpigmentation (PIH) is a common complication, especially in dark-complexioned skin. Isobutylamido thiazolyl resorcinol (ITR) has been reported as a preventive modality for ultraviolet B (UVB)-induced hyperpigmentation.
Aims: This study aims to evaluate the efficacy and safety of ITR for the prevention of laser-induced PIH.
Patients/methods: A randomized, evaluator-blinded study including 24 subjects with SLs was conducted. Three SLs of each patient were randomized into three groups, which were to apply ITR twice daily, once daily, and no application for 2 weeks. Thereafter, 532-nm QS Nd: YAG laser was performed. Incidence of laser-induced PIH, relative melanin index (RMI), mean luminance score (L*), hyperpigmentation score, and adverse events were recorded for 2 months post-laser.
Results: The incidence of PIH at the 4th week after laser treatment was significantly lower in the ITR twice-daily group compared to the no-application group (20.83% vs. 50%, p = 0.028). There was no statistically significant difference in RMI, mean L*, and hyperpigmentation score between treatments at all visits. No serious adverse events were reported regarding ITR application and laser treatment.
Conclusion: Two-week application of ITR prior to QS: Nd YAG laser treatment may potentially reduce the incidence of PIH. A longer duration of application, including after the laser procedure, may be more beneficial for the prevention of laser-induced PIH.
(© 2024 The Authors. Journal of Cosmetic Dermatology published by Wiley Periodicals LLC.)
References: Ortonne JP. Pigmentary changes of the ageing skin. Br J Dermatol. 1990;122(Suppl 35):21‐28. doi:10.1111/j.1365-2133.1990.tb16121.x.
Ortonne JP, Pandya AG, Lui H, Hexsel D. Treatment of solar lentigines. J Am Acad Dermatol. 2006;54(5 Suppl 2):S262‐S271. doi:10.1016/j.jaad.2005.12.043.
Rhodes AR, Harrist TJ, Momtaz TK. The PUVA‐induced pigmented macule: a lentiginous proliferation of large, sometimes cytologically atypical, melanocytes. J Am Acad Dermatol. 1983;9(1):47‐58. doi:10.1016/s0190-9622(83)70106-4.
Vachiramon V, Panmanee W, Techapichetvanich T, Chanprapaph K. Comparison of Q‐switched Nd: YAG laser and fractional carbon dioxide laser for the treatment of solar lentigines in Asians. Lasers Surg Med. 2016;48(4):354‐359. doi:10.1002/lsm.22472.
Vachiramon V, Iamsumang W, Triyangkulsri K. Q‐switched double frequency Nd:YAG 532‐nm nanosecond laser vs. double frequency Nd:YAG 532‐nm picosecond laser for the treatment of solar lentigines in Asians. Lasers Med Sci. 2018;33(9):1941‐1947. doi:10.1007/s10103-018-2560-3.
Vachiramon V, Namasondhi A, Anuntrangsee T, Jurairattanaporn N. Randomized, evaluator‐blinded comparative study of a potassium titanyl phosphate (KTP) 532‐nm picosecond laser and an alexandrite 755‐nm picosecond laser for the treatment of solar lentigines in Asians. J Cosmet Dermatol. 2022;21(10):4370‐4377. doi:10.1111/jocd.14831.
Chan MWM, Shek SY, Yeung CK, Chan HH. A prospective study in the treatment of Lentigines in Asian skin using 532 nm picosecond Nd:YAG laser. Lasers Surg Med. 2019;51(9):767‐773. doi:10.1002/lsm.23103.
Kawada A, Shiraishi H, Asai M, et al. Clinical improvement of solar lentigines and ephelides with an intense pulsed light source. Dermatol Surg. 2002;28(6):504‐508. doi:10.1046/j.1524-4725.2002.01175.x.
Kang HJ, Na JI, Lee JH, Roh MR, Ko JY, Chang SE. Postinflammatory hyperpigmentation associated with treatment of solar lentigines using a Q‐switched 532‐nm Nd: YAG laser: a multicenter survey. J Dermatolog Treat. 2017;28(5):447‐451. doi:10.1080/09546634.2016.1254330.
Negishi K, Akita H, Tanaka S, Yokoyama Y, Wakamatsu S, Matsunaga K. Comparative study of treatment efficacy and the incidence of post‐inflammatory hyperpigmentation with different degrees of irradiation using two different quality‐switched lasers for removing solar lentigines on Asian skin. J Eur Acad Dermatol Venereol. 2013;27(3):307‐312. doi:10.1111/j.1468-3083.2011.04385.x.
Davis EC, Callender VD. Postinflammatory hyperpigmentation: a review of the epidemiology, clinical features, and treatment options in skin of color. J Clin Aesthet Dermatol. 2010;3(7):20‐31.
Vachiramon V, Kositkuljorn C, Leerunyakul K, Chanprapaph K. Isobutylamido thiazolyl resorcinol for prevention of UVB‐induced hyperpigmentation. J Cosmet Dermatol. 2021;20(3):987‐992. doi:10.1111/jocd.13615.
Cheyasak N, Manuskiatti W, Maneeprasopchoke P, Wanitphakdeedecha R. Topical corticosteroids minimise the risk of postinflammatory hyper‐pigmentation after ablative fractional CO2 laser resurfacing in Asians. Acta Derm Venereol. 2015;95(2):201‐205. doi:10.2340/00015555-1899.
Rutnin S, Pruettivorawongse D, Thadanipon K, Vachiramon V. A prospective randomized controlled study of Oral Tranexamic acid for the prevention of Postinflammatory hyperpigmentation after Q‐switched 532‐nm Nd:YAG laser for solar Lentigines. Lasers Surg Med. 2019;51(10):850‐858. doi:10.1002/lsm.23135.
Mann T, Gerwat W, Batzer J, et al. Inhibition of human Tyrosinase requires molecular motifs distinctively different from mushroom Tyrosinase. J Invest Dermatol. 2018;138(7):1601‐1608. doi:10.1016/j.jid.2018.01.019.
Mann T, Scherner C, Röhm KH, Kolbe L. Structure‐activity relationships of Thiazolyl Resorcinols, potent and selective inhibitors of human Tyrosinase. Int J Mol Sci. 2018;19(3):690. doi:10.3390/ijms19030690.
Roggenkamp D, Dlova N, Mann T, et al. Effective reduction of post‐inflammatory hyperpigmentation with the tyrosinase inhibitor isobutylamido‐thiazolyl‐resorcinol (Thiamidol). Int J Cosmet Sci. 2021;43(3):292‐301. doi:10.1111/ics.12694.
Arrowitz C, Schoelermann AM, Mann T, Jiang LI, Weber T, Kolbe L. Effective Tyrosinase inhibition by Thiamidol results in significant improvement of mild to moderate Melasma. J Invest Dermatol. 2019;139(8):1691‐1698.e6. doi:10.1016/j.jid.2019.02.013.
Anderson RR, Parrish JA. Selective photothermolysis: precise microsurgery by selective absorption of pulsed radiation. Science. 1983;220(4596):524‐527. doi:10.1126/science.6836297.
Burd A, Zhu N, Poon VK. A study of Q‐switched Nd:YAG laser irradiation and paracrine function in human skin cells. Photodermatol Photoimmunol Photomed. 2005;21(3):131‐137. doi:10.1111/j.1600-0781.2005.00155.x.
Imokawa G, Yada Y, Morisaki N, Kimura M. Biological characterization of human fibroblast‐derived mitogenic factors for human melanocytes. Biochem J. 1998;330(Pt 3):1235‐1239. doi:10.1042/bj3301235.
Chaowattanapanit S, Silpa‐Archa N, Kohli I, Lim HW, Hamzavi I. Postinflammatory hyperpigmentation: a comprehensive overview: treatment options and prevention. J Am Acad Dermatol. 2017;77(4):607‐621. doi:10.1016/j.jaad.2017.01.036.
Virador VM, Muller J, Wu X, et al. Influence of alpha‐melanocyte‐stimulating hormone and ultraviolet radiation on the transfer of melanosomes to keratinocytes. FASEB J. 2002;16(1):105‐107. doi:10.1096/fj.01-0518fje.
Bolognia J, Murray M, Pawelek J. UVB‐induced melanogenesis may be mediated through the MSH‐receptor system. J Invest Dermatol. 1989;92(5):651‐656. doi:10.1111/1523-1747.ep12696836.
Hong JY, Lee HW, Park KY, Kim BJ, Kim MN. Brimonidine tartrate gel plus topical steroid for the prevention of laser therapy‐related postinflammatory hyperpigmentation. Dermatol Ther. 2018;31(5):e12657. doi:10.1111/dth.12657.
Lee SJ, Ahn GR, Seo SB, Park KY, Kim BJ, Nam KM. Topical brimonidine‐assisted laser treatment for the prevention of therapy‐related erythema and hyperpigmentation. J Cosmet Laser Ther. 2019;21(4):225‐227. doi:10.1080/14764172.2018.1516887.
Sirithanabadeekul P, Srieakpanit R. Intradermal tranexamic acid injections to prevent post‐inflammatory hyperpigmentation after solar lentigo removal with a Q‐switched 532‐nm Nd:YAG laser. J Cosmet Laser Ther. 2018;20(7–8):398‐404. doi:10.1080/14764172.2018.1444770.
Kato H, Araki J, Eto H, et al. A prospective randomized controlled study of oral tranexamic acid for preventing postinflammatory hyperpigmentation after Q‐switched ruby laser. Dermatol Surg. 2011;37(5):605‐610. doi:10.1111/j.1524-4725.2011.01957.x.
Wanitphakdeedecha R, Phuardchantuk R, Manuskiatti W. The use of sunscreen starting on the first day after ablative fractional skin resurfacing. J Eur Acad Dermatol Venereol. 2014;28(11):1522‐1528. doi:10.1111/jdv.12332.
West TB, Alster TS. Effect of pretreatment on the incidence of hyperpigmentation following cutaneous CO2 laser resurfacing. Dermatol Surg. 1999;25(1):15‐17. doi:10.1046/j.1524-4725.1999.08123.x.
فهرسة مساهمة: Keywords: aged spot; hydroquinone; hyperpigmentation; laser; resorcinol
المشرفين على المادة: 0 (Resorcinols)
تواريخ الأحداث: Date Created: 20240318 Date Completed: 20240619 Latest Revision: 20240808
رمز التحديث: 20240809
DOI: 10.1111/jocd.16287
PMID: 38497328
قاعدة البيانات: MEDLINE
الوصف
تدمد:1473-2165
DOI:10.1111/jocd.16287