دورية أكاديمية
Sebaceous carcinoma in a 54-year-old Black African man after cancer chemotherapy: a case report.
| العنوان: | Sebaceous carcinoma in a 54-year-old Black African man after cancer chemotherapy: a case report. |
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| المؤلفون: | Olaofe OO; Department of Morbid Anatomy and Forensic Medicine, Obafemi Awolowo University, Ile-Ife, Osun State, Nigeria. oolaofe@oauife.edu.ng., Adewara BA; Department of Ophthalmology, Obafemi Awolowo University, Ile-Ife, Osun State, Nigeria., Okongwu CC; Department of Morbid Anatomy and Forensic Medicine, Obafemi Awolowo University, Ile-Ife, Osun State, Nigeria., Abdullahi YO; Department of Surgery, Obafemi Awolowo University, Ile-Ife, Osun State, Nigeria. |
| المصدر: | Journal of medical case reports [J Med Case Rep] 2024 Mar 19; Vol. 18 (1), pp. 159. Date of Electronic Publication: 2024 Mar 19. |
| نوع المنشور: | Case Reports; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: BioMed Central Country of Publication: England NLM ID: 101293382 Publication Model: Electronic Cited Medium: Internet ISSN: 1752-1947 (Electronic) Linking ISSN: 17521947 NLM ISO Abbreviation: J Med Case Rep Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: [London] : BioMed Central, [2007- |
| مواضيع طبية MeSH: | Adenocarcinoma, Sebaceous*/pathology , Adenocarcinoma, Sebaceous*/surgery , Muir-Torre Syndrome* , Blepharoptosis* , Sebaceous Gland Neoplasms*/pathology , Sebaceous Gland Neoplasms*/surgery, Male ; Humans ; Middle Aged |
| مستخلص: | Background: Sebaceous carcinoma is a very rare malignant skin adnexal tumor that is occasionally aggressive. We have not seen a case of sebaceous carcinoma in our center in the last 10 years. It is extremely rare in Black Africans. Case Presentation: We described the case of a 55-year-old man African man who presented to our ophthalmologist with complaints of growth on the right upper eyelid for 8 months. He had surgery and chemotherapy for rectal carcinoma 6 years prior to presentation and received his last dose of chemotherapy 5 years before seeing our ophthalmologist. There was a history of spontaneous unprovoked bleeding from the lesion. He subsequently underwent surgical excision under general anesthesia. Histology of the mass showed an effaced architecture due to proliferating malignant epithelial cells disposed as trabecules, solid nests, and tongues. The microscopic features of widespread multivacuolated cytoplasm of the neoplastic cells led us to conclude that the tumor was a sebaceous carcinoma. The patient is alive and well. Conclusion: Sebaceous carcinoma is a rare malignant skin adnexal tumor in Black Africans. It can present as an eyelid mass with spontaneous bleeding. It can follow cancer chemotherapy either because of its association with other tumors in Muir-Torre syndrome or because of mutagenic effects of chemotherapeutic agents. (© 2024. The Author(s).) |
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| فهرسة مساهمة: | Keywords: African; Carcinoma; Case report; Eyelids; Muir–Torre syndrome; Sebaceous |
| تواريخ الأحداث: | Date Created: 20240319 Date Completed: 20240320 Latest Revision: 20240321 |
| رمز التحديث: | 20240321 |
| مُعرف محوري في PubMed: | PMC10949574 |
| DOI: | 10.1186/s13256-024-04460-z |
| PMID: | 38500211 |
| قاعدة البيانات: | MEDLINE |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 1752-1947 |
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| DOI: | 10.1186/s13256-024-04460-z |