دورية أكاديمية

Scratching beneath the surface: An evaluation of the management of scabies 2017-2023.

التفاصيل البيبلوغرافية
العنوان: Scratching beneath the surface: An evaluation of the management of scabies 2017-2023.
المؤلفون: Broster B; Brighton and Hove Sexual Health and Contraception Service, University Hospitals Sussex NHS Foundation Trust, Brighton, UK., Clarke A; Brighton and Hove Sexual Health and Contraception Service, University Hospitals Sussex NHS Foundation Trust, Brighton, UK., Iwuji C; Brighton and Hove Sexual Health and Contraception Service, University Hospitals Sussex NHS Foundation Trust, Brighton, UK., Soni S; Brighton and Hove Sexual Health and Contraception Service, University Hospitals Sussex NHS Foundation Trust, Brighton, UK.
المصدر: International journal of STD & AIDS [Int J STD AIDS] 2024 Jul; Vol. 35 (8), pp. 616-619. Date of Electronic Publication: 2024 Mar 27.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Sage Country of Publication: England NLM ID: 9007917 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1758-1052 (Electronic) Linking ISSN: 09564624 NLM ISO Abbreviation: Int J STD AIDS Subsets: MEDLINE
أسماء مطبوعة: Publication: Dec. 2012- : London : Sage
Original Publication: London, U.K. : Royal Society of Medicine Services, c1990-
مواضيع طبية MeSH: Scabies*/drug therapy , Scabies*/epidemiology , Ivermectin*/therapeutic use , Permethrin*/therapeutic use, Humans ; Male ; Female ; Adult ; Middle Aged ; Insecticides/therapeutic use ; Young Adult ; Adolescent ; United Kingdom/epidemiology ; Aged
مستخلص: Introduction: Possible resistance to recommended treatments for scabies has emerged recently. In response to anecdotal reports of a recent increase in treatment failure with permethrin, the British Association for Sexual Health and HIV (BASHH) released a statement alerting members to this.
Aims: To examine attendances and the treatment pathways for scabies cases seen at local sexual health clinics.
Methodology: A case note review of scabies attendances between January 2017 and December 2023 was conducted. Data collected included patient demographics, clinical information, and scabies treatment histories. Statistical analysis was performed.
Results: 143 patients attended with scabies. The number of scabies cases did not appear to increase significantly from 2017 to 2023 ( p = .09). There was significant increase in median number of treatments per case per year over time ( p = .013). The number of individuals needing second-line treatments increased significantly over time ( p -trend < 0.001).
Discussion: Individuals with scabies are requiring more treatments to clear infection. Use of ivermectin has risen in the last year suggesting that second-line treatment is increasingly needed for eradication. Whilst treatment failure may be due to non-compliance with treatment and decontamination efforts for both index and contacts, the more recent change in findings could be attributed to a fall in permethrin efficacy.
Competing Interests: Declaration of conflicting interestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
فهرسة مساهمة: Keywords: Europe; Scabies (Sarcoptes scabiei); location; other; parasitic disease; prevention; treatment
المشرفين على المادة: 70288-86-7 (Ivermectin)
509F88P9SZ (Permethrin)
0 (Insecticides)
تواريخ الأحداث: Date Created: 20240327 Date Completed: 20240728 Latest Revision: 20240728
رمز التحديث: 20240728
DOI: 10.1177/09564624241242167
PMID: 38536716
قاعدة البيانات: MEDLINE
الوصف
تدمد:1758-1052
DOI:10.1177/09564624241242167