دورية أكاديمية
أعرض في EDS

Atypical post-infectious glomerulonephritis with c-ANCA positivity followed by endocarditis.

التفاصيل البيبلوغرافية
العنوان: Atypical post-infectious glomerulonephritis with c-ANCA positivity followed by endocarditis.
المؤلفون: Ryou S; Division of Nephrology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea., Park H; Division of Nephrology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea., Chae SY; Division of Nephrology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea., Kim Y; Division of Nephrology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea., Choi YJ; Department of Hospital Pathology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea., Park CW; Division of Nephrology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.; Institute for Aging and Metabolic Diseases, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
المصدر: Nephrology (Carlton, Vic.) [Nephrology (Carlton)] 2024 Sep; Vol. 29 (9), pp. 607-611. Date of Electronic Publication: 2024 Mar 28.
نوع المنشور: Case Reports; Journal Article
اللغة: English
بيانات الدورية: Publisher: Blackwell Science Country of Publication: Australia NLM ID: 9615568 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1440-1797 (Electronic) Linking ISSN: 13205358 NLM ISO Abbreviation: Nephrology (Carlton) Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Carlton, Vic., Australia : Blackwell Science,
مواضيع طبية MeSH: Antibodies, Antineutrophil Cytoplasmic*/blood , Antibodies, Antineutrophil Cytoplasmic*/immunology , Endocarditis, Bacterial*/diagnosis , Endocarditis, Bacterial*/microbiology , Endocarditis, Bacterial*/immunology , Endocarditis, Bacterial*/complications , Endocarditis, Bacterial*/drug therapy , Glomerulonephritis*/immunology , Glomerulonephritis*/microbiology , Glomerulonephritis*/diagnosis , Glomerulonephritis*/etiology , Glomerulonephritis*/drug therapy , Aggregatibacter actinomycetemcomitans*/isolation & purification , Aggregatibacter actinomycetemcomitans*/immunology, Humans ; Male ; Adult ; Acute Kidney Injury/etiology ; Acute Kidney Injury/immunology ; Acute Kidney Injury/diagnosis ; Acute Kidney Injury/microbiology ; Pasteurellaceae Infections/diagnosis ; Pasteurellaceae Infections/microbiology ; Treatment Outcome ; Heart Valve Prosthesis Implantation ; Biopsy ; Anti-Bacterial Agents/therapeutic use ; Biomarkers/blood ; Nephritis, Interstitial/immunology ; Nephritis, Interstitial/diagnosis ; Nephritis, Interstitial/microbiology ; Nephritis, Interstitial/etiology ; Nephritis, Interstitial/drug therapy
مستخلص: Post-infectious glomerulonephritis (PIGN), an uncommon variety of glomerulonephritis (GN), is characterized by emergence of nephritic syndrome within a few weeks following an infectious event. PIGN typically presents as a mild condition and tends to resolve by the time of diagnosis for GN. Aggregatibacter actinomycetemcomitans belongs to the HACEK group of bacteria, which constitutes less than 3% of bacteria responsible for community-acquired infective endocarditis. We present a case of 29-year-old man suspected of lymphoma with B-symptoms along with severe splenomegaly and nephromegaly. Shortly after, he developed an episode of nephritic syndrome accompanied by acute kidney injury (AKI) and high titers of cytoplasmic ANCA (c-ANCA)-positivity. Kidney biopsy revealed PIGN with tubulointerstitial nephritis. Despite treatment with antibiotics and corticosteroid, he visited the emergency room due to worsening dyspnea and multi-organ failure. An echocardiogram showed a bicuspid aortic valve with vegetation unseen on previous echocardiogram. He underwent aortic valve replacement immediately without adverse events. Four months after valve replacement, his renal function and cardiac performance have remained stable. We report a case of PIGN with AKI and high titers of c-ANCA appearing later as an infective endocarditis due to Aggregatibacter actinomycetemcomitans. With careful clinical observation and appropriate and timely management, satisfactory outcomes for patient health are possible.
(© 2024 The Authors. Nephrology published by John Wiley & Sons Australia, Ltd on behalf of Asian Pacific Society of Nephrology.)
References: Sethi S, Fervenza FC, Zhang Y, et al. Atypical postinfectious glomerulonephritis is associated with abnormalities in the alternative pathway of complement. Kidney Int. 2013;83(2):293‐299.
Nadasdy T, Hebert LA. Infection‐related glomerulonephritis: understanding mechanisms. Semin Nephrol. 2011;31(4):369‐375.
Nasr SH, Fidler ME, Valeri AM, et al. Postinfectious glomerulonephritis in the elderly. J Am Soc Nephrol. 2011;22(1):187‐195.
Berbari EF, Cockerill FR 3rd, Steckelberg JM. Infective endocarditis due to unusual or fastidious microorganisms. Mayo Clin Proc. 1997;72(6):532‐542.
Viallard JF, Bonnet S, Couzi L, et al. Glomerulonephritis caused by Actinobacillus actinomycetemcomitans mimicking c‐ANCA‐positive vasculitis. Nephrol Dial Transplant. 2002;17(4):663‐665.
Zambon JJ. Actinobacillus actinomycetemcomitans in human periodontal disease. J Clin Periodontol. 1985;12(1):1‐20.
Shah GM, Winer RL. Glomerulonephritis associated with endocarditis caused by Actinobacillus actinomycetemcomitans. Am J Kidney Dis. 1981;1(2):113‐115.
van der Geest KSM, Brouwer E, Sanders JS, et al. Towards precision medicine in ANCA‐associated vasculitis. Rheumatology. 2018;57(8):1332‐1339.
Cronec D, Cronec‐Le Gall E, Fervenza FC, Specks U. ANCA‐associated vasculitis – clinical utility of using ANCA specificity to classify patients. Nat Rev Rheumatol. 2016;12(10):570‐579.
Boils CL, Nasr SH, Walker PD, Couser WG, Larsen CP. Update on endocarditis‐associated glomerulonephritis. Kidney Int. 2015;87(6):1241‐1249.
McAdoo SP, Hall A, Levy J, et al. Proteinase‐3 antineutrophil cytoplasm antibody positivity in patients without primary systemic vasculitis. J Clin Rheumatol. 2012;18:336‐340.
Houben E, Bax WA, van Dam B, et al. Diagnosing ANCA‐associated vasculitis in ANCA positive patients: a retrospective analysis on the role of clinical symptoms and the ANCA titre. Medicine. 2016;95:e5096.
Belloch SL, Salavert M, Lacruz J, López‐Aldeguer J, Pérez‐Bellés C. Subacute endocarditis caused by Actinobacillus actinomycetemcomitans. Enferm Infecc Microbiol Clin. 2000;18(8):379‐384.
Pereira SC, Abrantes AL, António PS, et al. Infective endocarditis risk in patients with bicuspid aortic valve: systematic review and meta‐analysis. Int J Cardiol Heart Vasc. 2023;47:101249.
Chua HS, Soh YH, Loong SK, et al. Aggregatibacter actinomycetemcomitans endocarditis in a patient with chronic periodontitis: a case report. Ann Clin Microbiol Antimicrob. 2023;19(2):72‐75.
معلومات مُعتمدة: RS-2023-00251436 National Research Foundation of Korea
فهرسة مساهمة: Keywords: acute kidney injury; c‐ANCA‐positive vasculitis; infective endocarditis; post‐infectious glomerulonephritis
المشرفين على المادة: 0 (Antibodies, Antineutrophil Cytoplasmic)
0 (Anti-Bacterial Agents)
0 (Biomarkers)
تواريخ الأحداث: Date Created: 20240328 Date Completed: 20240816 Latest Revision: 20240816
رمز التحديث: 20240816
DOI: 10.1111/nep.14298
PMID: 38544475
قاعدة البيانات: MEDLINE
الوصف
تدمد:1440-1797
DOI:10.1111/nep.14298