دورية أكاديمية
Relationship between idiopathic interstitial pneumonias (IIPs) and connective tissue disease-related interstitial lung disease (CTD-ILD): A narrative review.
| العنوان: | Relationship between idiopathic interstitial pneumonias (IIPs) and connective tissue disease-related interstitial lung disease (CTD-ILD): A narrative review. |
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| المؤلفون: | Enomoto N; Second Division, Department of Internal Medicine, Hamamatsu University School of Medicine, 1-20-1 Handayama, Hamamatsu, 431-3192, Japan; Health Administration Center, Hamamatsu University School of Medicine, 1-20-1 Handayama, Hamamatsu, 431-3192, Japan. Electronic address: norieno@hama-med.ac.jp. |
| المصدر: | Respiratory investigation [Respir Investig] 2024 May; Vol. 62 (3), pp. 465-480. Date of Electronic Publication: 2024 Apr 01. |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101581124 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2212-5353 (Electronic) Linking ISSN: 22125345 NLM ISO Abbreviation: Respir Investig Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Amsterdam : Elsevier |
| مواضيع طبية MeSH: | Lung Diseases, Interstitial*/diagnosis , Idiopathic Interstitial Pneumonias*/complications , Idiopathic Interstitial Pneumonias*/diagnosis , Idiopathic Pulmonary Fibrosis*/complications , Connective Tissue Diseases*/complications , Connective Tissue Diseases*/diagnosis, Humans ; Aged ; Prognosis |
| مستخلص: | While idiopathic interstitial pneumonia (IIP) centering on idiopathic pulmonary fibrosis (IPF) is the most prevalent interstitial lung disease (ILD), especially in the older adult population, connective tissue disease (CTD)-related ILD is the second most prevalent ILD. The pathogenesis of IPF is primarily fibrosis, whereas that of other ILDs, particularly CTD-ILD, is mainly inflammation. Therefore, a precise diagnosis is crucial for selecting appropriate treatments, such as antifibrotic or immunosuppressive agents. In addition, some patients with IIP have CTD-related features, such as arthritis and skin eruption, but do not meet the criteria for any CTD, this is referred to as interstitial pneumonia with autoimmune features (IPAF). IPAF is closely associated with idiopathic nonspecific interstitial pneumonia (iNSIP) and cryptogenic organizing pneumonia (COP). Furthermore, patients with iNSIP or those with NSIP with OP overlap frequently develop polymyositis/dermatomyositis after the diagnosis of IIP. Acute exacerbation of ILD, the most common cause of death, occurs more frequently in patients with IPF than in those with other ILDs. Although acute exacerbation of CTD-ILD occurs at a low rate of incidence, patients with rheumatoid arthritis, microscopic polyangiitis, or systemic sclerosis experience more acute exacerbation of CTD-ILD than those with other CTD. In this review, the features of each IIP, focusing on CTD-related signatures, are summarized, and the pathogenesis and appropriate treatments to improve the prognoses of patients with various ILDs are discussed. Competing Interests: Declaration of competing interest NE received a grant from Boehringer Ingelheim Japan Co., Ltd. (Copyright © 2024 The Japanese Respiratory Society. Published by Elsevier B.V. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Acute exacerbation; Connective tissue disease; Idiopathic interstitial pneumonia; Idiopathic pulmonary fibrosis; Interstitial pneumonia with autoimmune features |
| تواريخ الأحداث: | Date Created: 20240402 Date Completed: 20240422 Latest Revision: 20240422 |
| رمز التحديث: | 20240422 |
| DOI: | 10.1016/j.resinv.2024.03.006 |
| PMID: | 38564878 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 2212-5353 |
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| DOI: | 10.1016/j.resinv.2024.03.006 |