دورية أكاديمية
Short term outcomes of neonatal opioid withdrawal syndrome: a comparison of two approaches.
| العنوان: | Short term outcomes of neonatal opioid withdrawal syndrome: a comparison of two approaches. |
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| المؤلفون: | Singh R; Department of Pediatrics, Tufts University School of Medicine, Boston, MA, USA. rachana.singh1@tuftsmedicine.org., Melvin P; Center for Applied Pediatric Quality Analytics, Boston Children's Hospital, Boston, MA, USA., Wachman EM; Department of Pediatrics, Boston Medical Center, Boston, MA, USA., Rothstein R; Department of Pediatrics, Baystate Children's Hospital, Springfield, MA, USA., Schiff DM; Divisions of Newborn Medicine and General Academic Pediatrics, Massachusetts General for Children, Boston, MA, USA., Murzycki J; Department of Pediatrics, Tufts University School of Medicine, Boston, MA, USA., VanVleet M; Division of Newborn Medicine, Baystate Franklin Medical Center, Greenfield, MA, USA., Gupta M; Division of Newborn Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA., Davis JM; Department of Pediatrics, Tufts University School of Medicine, Boston, MA, USA.; The Tufts Clinical and Translational Science Institute, Boston, MA, USA. |
| مؤلفون مشاركون: | PNQIN Collaborative of Massachusetts |
| المصدر: | Journal of perinatology : official journal of the California Perinatal Association [J Perinatol] 2024 Aug; Vol. 44 (8), pp. 1137-1145. Date of Electronic Publication: 2024 Apr 02. |
| نوع المنشور: | Journal Article; Comparative Study |
| اللغة: | English |
| بيانات الدورية: | Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 8501884 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5543 (Electronic) Linking ISSN: 07438346 NLM ISO Abbreviation: J Perinatol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2001- : New York, NY : Nature Publishing Group Original Publication: [Philadelphia, Pa. : W.B. Saunders, c1984- |
| مواضيع طبية MeSH: | Neonatal Abstinence Syndrome*/therapy , Length of Stay*/statistics & numerical data, Humans ; Infant, Newborn ; Retrospective Studies ; Female ; Male ; Analgesics, Opioid/adverse effects ; Analgesics, Opioid/therapeutic use ; Pregnancy ; Opioid-Related Disorders ; Logistic Models |
| مستخلص: | Objective: To evaluate outcomes in opioid exposed neonates (OENs) assessed by the Eat, Sleep, Console (ESC) tool compared to the Finnegan Neonatal Abstinence Scoring System (FNASS). Methods: Retrospective analysis of a statewide database of OENs from 2017 to 2020 with birthing hospitals classified based on the assessment tool used. Four main outcomes were examined using multivariable and Poisson logistic regression models. Results: Of 2375 OENs, 42.1% received pharmacotherapy (PT) with a consistent decrease in PT, length of treatment (LOT), and length of stay (LOS) over the study period. There was no change in use of mother's own milk (MoM). While outcomes were significantly associated with several specific variables, there were no differences in outcomes between assessment methods. Conclusion: While there was a significant decrease over time in PT, LOT, and LOS, improvements were independent of the assessment tool used and likely related to the increased use of non-pharmacologic care. (© 2024. The Author(s), under exclusive licence to Springer Nature America, Inc.) |
| References: | https://nida.nih.gov/research-topics/trends-statistics/overdose-death-rates . Accessed 10 Jun 2023. Keyes KM, Rutherford C, Hamilton A, Barocas JA, Gelberg KH, Mueller PP, et al. What is the prevalence of and trend in opioid use disorder in the United States from 2010 to 2019? Using multiplier approaches to estimate prevalence for an unknown population size. Drug Alcohol Depend Rep. 2022;3:100052. (PMID: 10.1016/j.dadr.2022.100052357839949248998) Hirai AH, Ko JY, Owens PL, Stocks C, Patrick SW. Neonatal abstinence syndrome and maternal opioid-related diagnoses in the US, 2010-2017. JAMA. 2021;325:146–55. (PMID: 10.1001/jama.2020.24991334335767804920) Patrick SW, Barfield WD, Poindexter B, Committee on Fetus and Newborn, Committee on Substance Use and Prevention. Neonatal Opioid Withdrawal Syndrome. Pediatrics. 2020;146:e2020029074. (PMID: 10.1542/peds.2020-02907433106341) Finnegan LP, Connaughton JF Jr, Kron RE, Emich JP. Neonatal abstinence syndrome: assessment and management. Addict Dis. 1975;2:141–58. (PMID: 1163358) Devlin LA, Breeze JL, Terrin N, Pomar EG, Bada H, Finnegan LP, et al. Association of a simplified Finnegan neonatal abstinence scoring Method with the need for pharmacologic treatment for neonatal abstinence syndrome. JAMA Netw Open. 2020;3:e202275. (PMID: 10.1001/jamanetworkopen.2020.2275322675137142377) Grossman MR, Lipshaw MJ, Osborn RR, Berkwitt AK. A novel approach to assessing infants with neonatal abstinence syndrome. Hosp Pediatr. 2018;8:1–6. (PMID: 10.1542/hpeds.2017-012829263121) Wachman EM, Houghton M, Melvin P, Isley BC, Murzycki J, Singh R, et al. A quality improvement initiative to implement the eat, sleep, console neonatal opioid withdrawal syndrome care method in Massachusetts’ PNQIN collaborative. J Perinatol. 2020;40:1560–9. (PMID: 10.1038/s41372-020-0733-y32678314) Young LW, Ounpraseuth ST, Merhar SL, Hu Z, Simon AE, Bremer AA et al. ACT NOW Collaborative. Eat, sleep, console approach or usual care for neonatal opioid withdrawal. N Engl J Med. 2023;388:2326–37. Singh R, Houghton M, Melvin P, Wachman EM, Diop H, Iverson R, et al. Predictors of pharmacologic therapy for neonatal opioid withdrawal syndrome: a retrospective analysis of a statewide database. J Perinatol. 2021;41:1381–8. (PMID: 10.1038/s41372-021-00969-z33608626) Singh R, Rothstein R, Ricci K, Vistainer P, Shenberger J, Attwood E, et al. Partnering with parents to improve outcomes for substance exposed newborns—a pilot program. J Perinatol. 2020;40:1041–9. (PMID: 10.1038/s41372-020-0662-932203180) Kilpatrick SJ, Papile LA, Macones GA. Organization of perinatal healthcare. In: Guidelines for Perinatal Care. 8 th Edition:1-36. American Academy of Pediatrics and American College of Obstetrics and Gynecology; 2017. https://matracking.ehs.state.ma.us/eohhs_regions/eohhs_regions.html . Accessed 10 Aug 2023. Pregnancy to Early Life Longitudinal Data System (PELL). NAS Dashboard New Data v6a - 2023-02-21 - MHT (mass.gov). Accessed 10 Aug 2023 https://www.mass.gov/info-details/neonatal-abstinence-syndrome-nas-data . Jilani SM, Jordan CJ, Jansson LM, Davis JM. Definitions of neonatal abstinence syndrome in clinical studies of mothers and infants: an expert literature review. J Perinatol. 2021;41:1364–71. (PMID: 10.1038/s41372-020-00893-8335148788225507) Jilani SM, Jones HE, Davis JM. Implementation of a standardized clinical definition of opioid withdrawal in the neonate: challenges and opportunities. JAMA. 2022;327:1643–4. (PMID: 10.1001/jama.2022.540635420630) Jones HE, Kaltenbach K, Heil SH, Stein S. M., Coyle M. G., Arria A. M. et al. Neonatal abstinence syndrome after methadone or buprenorphine exposure. N. Engl J Med. 2010;363:2320–31. (PMID: 10.1056/NEJMoa1005359211425343073631) Singh R, Davis JM. Escaping the Finnegan - Is it time? Semin Fetal Neonatal Med. 2021;26:101218. (PMID: 10.1016/j.siny.2021.10121833663940) Czynski AJ, Davis JM, Dansereau LM, Engelhardt B, Marro P, Bogen DL, et al. Neurodevelopmental outcomes of neonates randomized to morphine or methadone for treatment of neonatal abstinence syndrome. J Pediatr. 2020;219:146–51.e1. (PMID: 10.1016/j.jpeds.2019.12.018319876537161698) Jones H, Baer G, Davis JM. Neonatal Abstinence Syndrome. In: Boardman JP, Groves A, Ramasethu J editors. Avery and MacDonald’s Neonatology, Pathophysiology and Management of the Newborn, 8 th edition, J.B. Lippincott Co., Philadelphia, PA, 2021. Pahl A, Young L, Buss-Frank ME, Marcellus L, Soll R. Non-pharmacological care for opioid withdrawal in newborns. Cochrane Database of Systematic Reviews 2020, Art. No. : CD013217. Accessed Oct 31 2023. Morrison TM, MacMillan KDL, Melvin P, Singh R, Murzycki J, VanVleet MW, et al. Neonatal opioid withdrawal syndrome: a comparison of as-needed pharmacotherapy. Hosp Pediatr. 2022;12:530–8. (PMID: 10.1542/hpeds.2021-00630135403199) |
| المشرفين على المادة: | 0 (Analgesics, Opioid) |
| تواريخ الأحداث: | Date Created: 20240402 Date Completed: 20240805 Latest Revision: 20240805 |
| رمز التحديث: | 20240806 |
| DOI: | 10.1038/s41372-024-01953-z |
| PMID: | 38565652 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1476-5543 |
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| DOI: | 10.1038/s41372-024-01953-z |