دورية أكاديمية
In the fight against HIV/AIDS: the arduous implementation of government-funded pre-exposure prophylaxis programme in Taiwan.
| العنوان: | In the fight against HIV/AIDS: the arduous implementation of government-funded pre-exposure prophylaxis programme in Taiwan. |
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| المؤلفون: | Huang HY; Division of Chronic Infectious Diseases, Taiwan Centers for Disease Control, Taipei, Taiwan., Huang JR; Division of Chronic Infectious Diseases, Taiwan Centers for Disease Control, Taipei, Taiwan., Chan PC; Division of Chronic Infectious Diseases, Taiwan Centers for Disease Control, Taipei, Taiwan pcanita.tw@cdc.gov.tw.; Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan.; Division of Pediatric Infectious Diseases, Department of Pediatrics, National Taiwan University Hospital, Taipei, Taiwan., Lee CC; Division of Chronic Infectious Diseases, Taiwan Centers for Disease Control, Taipei, Taiwan. |
| المصدر: | Sexually transmitted infections [Sex Transm Infect] 2024 May 31; Vol. 100 (4), pp. 216-221. Date of Electronic Publication: 2024 May 31. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: BMJ Pub. Group Country of Publication: England NLM ID: 9805554 Publication Model: Electronic Cited Medium: Internet ISSN: 1472-3263 (Electronic) Linking ISSN: 13684973 NLM ISO Abbreviation: Sex Transm Infect Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: London : BMJ Pub. Group, c1998- |
| مواضيع طبية MeSH: | Pre-Exposure Prophylaxis*/methods , HIV Infections*/prevention & control , HIV Infections*/epidemiology, Humans ; Male ; Taiwan/epidemiology ; Adult ; Retrospective Studies ; Female ; Sexual Behavior ; Surveys and Questionnaires ; Sexual Partners ; Young Adult ; Financing, Government ; Risk-Taking ; Seroconversion ; Middle Aged ; Government Programs |
| مستخلص: | Introduction: The government-funded pre-exposure prophylaxis (PrEP) programme was targeted to those aged under 30 years or serodiscordant couples and implemented in September 2018-October 2020 in Taiwan. The study aimed to examine the effectiveness of the programme and the relationship between sexually transmitted disease (STD) and HIV seroconversion. Methods: This study was a retrospective cohort analysis with questionnaires designed for participants who joined the aforementioned programme in the PrEP-designated hospitals. The questionnaires included sociodemographic factors, sexual risk behaviours, number and types of sexual partners, and usage of narcotics filled in at the beginning of the programme and every 3 months. The McNemar test was used for the paired questionnaire analysis. The HIV seroconversion status among STD-notified patients nationwide was confirmed by using the data linkage method, followed up until October 2021 with stratification of PrEP programme participation or not. Results: The programme recruited 2155 people. 11 participants (0.5%) had seroconversion within the programme, while 26 (1.2%) had seroconversion after withdrawing from the programme. Overall, 1892 subjects with repeated questionnaires were included in the analysis for behaviour changes with median follow-up of 289 days. After joining the programme, 94.7% of them claimed that they had sexual behaviours: the rate of those who had condomless sex rose to 5.5% (p<0.001) and the rate of those who used narcotics decreased to 2% (p<0.001), compared with their response in the pre-questionnaire. Notably, the frequency of non-use of narcotics in recent 3 months increased from 16.9% to 38.4% in the pre-questionnaire and post-questionnaire responses, among the 177 who had claimed narcotics usage in recent 12 months (p=0.003). More HIV seroconversion was found among patients with STD who did not join the programme than those who joined the programme (8.7% vs 4.9%, p=0.031). Conclusions: The government-funded programme showed HIV case reduction and positive changes in health behaviours except for condomless sex which had increased prevalence. The reduction of HIV cases was also observed among people with STD. More resources should be allocated to the PrEP programme. Competing Interests: Competing interests: None declared. (© Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY. Published by BMJ.) |
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| فهرسة مساهمة: | Keywords: HIV; HIV Seropositivity; HIV pre-exposure prophylaxis |
| تواريخ الأحداث: | Date Created: 20240404 Date Completed: 20240531 Latest Revision: 20240622 |
| رمز التحديث: | 20240622 |
| مُعرف محوري في PubMed: | PMC11187399 |
| DOI: | 10.1136/sextrans-2023-055917 |
| PMID: | 38575314 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1472-3263 |
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| DOI: | 10.1136/sextrans-2023-055917 |