دورية أكاديمية

Self-reported side effects of COVID-19 vaccines among health professions students in India.

التفاصيل البيبلوغرافية
العنوان: Self-reported side effects of COVID-19 vaccines among health professions students in India.
المؤلفون: Majumder MAA; Faculty of Medical Sciences, The University of the West Indies, Cave Hill Campus, Bridgetown, Barbados.; Public Health Foundation of Bangladesh, Dhaka, Bangladesh., Bharatha A; Faculty of Medical Sciences, The University of the West Indies, Cave Hill Campus, Bridgetown, Barbados., Kumar S; Karnavati University, Ahmedabad, Gujarat, India., Chatterjee M; Shri Ramkrishna Institute of Medical Science, Durgapur, West Bengal, India., Gupta S; Faculty of Medical Sciences, The University of the West Indies, Cave Hill Campus, Bridgetown, Barbados., Harewood H; Faculty of Medical Sciences, The University of the West Indies, Cave Hill Campus, Bridgetown, Barbados., Singh K; Faculty of Medical Sciences, The University of the West Indies, Cave Hill Campus, Bridgetown, Barbados., Johnson W; Sree Balaji Medical College and Hospital, Chennai, Tamil Nadu, India., Rajasundaram A; Sree Balaji Medical College and Hospital, Chennai, Tamil Nadu, India., Dutta SB; Department of Medical Surgical Nursing (Critical care nursing), Shri Anand Institute of Nursing, Rajkot, Gujarat, India., Prasad SV; Govt. Medical College, Shivpuri, Madhya Pradesh, India., Rahman S; American University of Integrative Sciences (AUIS), Bridgetown, Barbados., Kabir R; Anglia Ruskin University, Chelmsford, Essex, United Kingdom., Parsa AD; Anglia Ruskin University, Chelmsford, Essex, United Kingdom., Gaur U; Faculty of Medical Sciences, The University of the West Indies, Cave Hill Campus, Bridgetown, Barbados., Rabbi AMF; Department of Population Sciences, University of Dhaka, Dhaka, Bangladesh., Krishnamurthy K; Faculty of Medical Sciences, The University of the West Indies, Cave Hill Campus, Bridgetown, Barbados., Mohammad S; Health Education Department, Empower Me First College, Geneva, Switzerland., Chode V; Queen Elizabeth Hospital, Bridgetown, Barbados., Haque M; National Defence University of Malaysia, Kuala Lumpur, Malaysia., Campbell MH; Faculty of Medical Sciences, The University of the West Indies, Cave Hill Campus, Bridgetown, Barbados.
المصدر: PeerJ [PeerJ] 2024 Apr 05; Vol. 12, pp. e17083. Date of Electronic Publication: 2024 Apr 05 (Print Publication: 2024).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: PeerJ Inc Country of Publication: United States NLM ID: 101603425 Publication Model: eCollection Cited Medium: Internet ISSN: 2167-8359 (Electronic) Linking ISSN: 21678359 NLM ISO Abbreviation: PeerJ Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Corte Madera, CA : PeerJ Inc.
مواضيع طبية MeSH: COVID-19*/epidemiology , Students, Health Occupations*, Female ; Humans ; ChAdOx1 nCoV-19 ; COVID-19 Vaccines/adverse effects ; Cross-Sectional Studies ; Fatigue ; Fever ; Headache ; Health Occupations ; India/epidemiology ; Pain ; Self Report ; Male
مستخلص: Studies focusing on the safety and common side effects of vaccines play a crucial role in enhancing public acceptance of vaccination. Research is scarce regarding the usage of COVID-19 vaccines and the side effects experienced by health professions students in India and other countries. This study aimed to document self-reported side effects associated with COVID-19 vaccination among medical and dental students of six medical and dental colleges and teaching hospitals in four states (Tamil Nadu, Madhya Pradesh, Gujarat, and West Bengal) of India. A cross-sectional survey using purposive sampling of medical and dental students was conducted from 26 April to 26 May 2021. Data was collected using a Google Forms questionnaire capturing information regarding receiving COVID-19 vaccines, side effects and symptoms, onset and duration of symptoms, use of treatment to alleviate symptoms, awareness of haematologic risks associated with vaccination, and side effects from previous (non-COVID-19) vaccinations. The majority (94.5%) of participants received both doses of the Covishield/AstraZeneca COVID-19 vaccine. Among participants ( n  = 492), 45.3% ( n  = 223) reported one or more side effects. The most frequently reported side effects were soreness of the injected arm (80.3%), tiredness (78.5%), fever (71.3%), headache (64.1%), and hypersomnia (58.7%). The two most common severe symptoms were fever (14.8%) and headache (13%). Most side effects appeared on the day of vaccination: soreness of the injection site (57%), fever (43.1%), and tiredness (42.6%). Most reported symptoms persisted for one to three days-soreness of the injection site (53%), fever (47.1%), and headache (42.6%). Logistic regression showed that women were almost 85% less likely to report side effects. The study's findings corroborate the safety of the Covishield/AstraZeneca vaccine's first dose, evidenced by the relatively minor and transient nature of the side effects. However, the study underscores the necessity for ongoing research to assess the long-term impacts of COVID-19 vaccines, especially in the context of booster doses, thereby contributing to the global understanding of vaccine safety and efficacy.
Competing Interests: Russell Kabir is an Academic Editor for PeerJ. The other authors declare that they have no competing interests.
(©2024 Majumder et al.)
References: Expert Rev Vaccines. 2022 Aug;21(8):1011-1014. (PMID: 35475680)
Lancet Infect Dis. 2021 Jul;21(7):939-949. (PMID: 33930320)
Open Forum Infect Dis. 2021 May 19;9(2):ofab259. (PMID: 35071679)
Pharm Pract (Granada). 2022 Jul-Sep;20(3):2689. (PMID: 36733523)
BMJ. 2022 Feb 4;376:o298. (PMID: 35121611)
J Family Med Prim Care. 2022 Jun;11(6):3224-3229. (PMID: 36119236)
J Assoc Physicians India. 2022 Jul;70(7):11-12. (PMID: 35833411)
Cureus. 2022 Jan 18;14(1):e21376. (PMID: 35198288)
Vaccines (Basel). 2022 Feb 27;10(3):. (PMID: 35335005)
Ther Adv Drug Saf. 2022 Sep 5;13:20420986221116452. (PMID: 36072284)
NPJ Vaccines. 2019 Sep 24;4:39. (PMID: 31583123)
Vaccines (Basel). 2022 Jun 15;10(6):. (PMID: 35746556)
FASEB Bioadv. 2022 Mar 24;4(6):379-390. (PMID: 35601057)
Int Immunopharmacol. 2021 Nov;100:108136. (PMID: 34587578)
SN Compr Clin Med. 2020;2(10):1777-1789. (PMID: 32904710)
Indian J Med Res. 2022 Jan;155(1):123-128. (PMID: 35859438)
Vaccines (Basel). 2022 Dec 13;10(12):. (PMID: 36560545)
J Med Virol. 2022 Jun;94(6):2453-2459. (PMID: 35149993)
Cureus. 2021 Sep 15;13(9):e17990. (PMID: 34667668)
Med J Armed Forces India. 2021 Jul;77:S283-S288. (PMID: 34334895)
J Glob Health. 2021 Jun 26;11:03083. (PMID: 34221355)
Lancet Infect Dis. 2022 Jan;22(1):43-55. (PMID: 34480857)
J Inflamm Res. 2021 Feb 26;14:527-550. (PMID: 33679136)
Expert Rev Anti Infect Ther. 2020 Dec;18(12):1201-1211. (PMID: 32749914)
Vaccine. 2015 Aug 14;33(34):4161-4. (PMID: 25896383)
Expert Rev Clin Pharmacol. 2021 May;14(5):601-621. (PMID: 33705239)
Front Med (Lausanne). 2022 Nov 09;9:1023507. (PMID: 36438045)
Int J Gen Med. 2021 Jul 27;14:3909-3927. (PMID: 34349544)
Hum Vaccin Immunother. 2021 Oct 3;17(10):3348-3354. (PMID: 34096836)
Nature. 2022 Aug 26;:. (PMID: 36028769)
NPJ Vaccines. 2021 Apr 21;6(1):60. (PMID: 33883557)
Vaccines (Basel). 2021 Feb 16;9(2):. (PMID: 33669441)
Indian J Clin Biochem. 2021 Oct;36(4):427-439. (PMID: 33814753)
Indian J Clin Biochem. 2021 Jan;36(1):108-111. (PMID: 33162692)
Vaccines (Basel). 2021 May 26;9(6):. (PMID: 34073382)
Infect Drug Resist. 2020 Dec 14;13:4427-4438. (PMID: 33364790)
J Multidiscip Healthc. 2023 Jan 19;16:161-174. (PMID: 36700174)
J Inflamm Res. 2021 May 21;14:2091-2110. (PMID: 34045883)
J Med Ethics. 2024 Jan 23;50(2):126-138. (PMID: 36600579)
Indian J Med Res. 2022 May-Jun;155(5&6):518-525. (PMID: 36348600)
Expert Opin Drug Saf. 2021 Sep;20(9):1125-1136. (PMID: 34162299)
Perspect Psychol Sci. 2021 Mar;16(2):191-203. (PMID: 33501900)
J Multidiscip Healthc. 2021 Nov 30;14:3309-3319. (PMID: 34876817)
EClinicalMedicine. 2021 Jul 23;38:101038. (PMID: 34505032)
Expert Rev Vaccines. 2021 Sep;20(9):1167-1175. (PMID: 34224292)
فهرسة مساهمة: Keywords: COVID-19 vaccine; Covishield/AstraZeneca vaccines; Dental students; Medical students; Side effects; Vaccine hesitancy
المشرفين على المادة: B5S3K2V0G8 (ChAdOx1 nCoV-19)
0 (COVID-19 Vaccines)
تواريخ الأحداث: Date Created: 20240409 Date Completed: 20240410 Latest Revision: 20240418
رمز التحديث: 20240418
مُعرف محوري في PubMed: PMC11000642
DOI: 10.7717/peerj.17083
PMID: 38590705
قاعدة البيانات: MEDLINE
الوصف
تدمد:2167-8359
DOI:10.7717/peerj.17083