دورية أكاديمية
Hox-A2 protein expression in avian jaws cartilages and muscle primordia development.
| العنوان: | Hox-A2 protein expression in avian jaws cartilages and muscle primordia development. |
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| المؤلفون: | Louryan S; Laboratoire d'anatomie, biomécanique et organogenèse, faculté de médecine, université Libre de Bruxelles, route de Lennik, 808 (CP 619), 1070 Bruxelles, Belgium. Electronic address: slouryan@ulb.ac.be., Duterre M; Laboratoire d'anatomie, biomécanique et organogenèse, faculté de médecine, université Libre de Bruxelles, route de Lennik, 808 (CP 619), 1070 Bruxelles, Belgium., Vanmuylder N; Laboratoire d'anatomie, biomécanique et organogenèse, faculté de médecine, université Libre de Bruxelles, route de Lennik, 808 (CP 619), 1070 Bruxelles, Belgium. |
| المصدر: | Morphologie : bulletin de l'Association des anatomistes [Morphologie] 2024 Sep; Vol. 108 (362), pp. 100780. Date of Electronic Publication: 2024 Apr 11. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Masson Country of Publication: France NLM ID: 9814314 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1286-0115 (Print) Linking ISSN: 12860115 NLM ISO Abbreviation: Morphologie Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Original Publication: Vandoeuvre-lès-Nancy [France] : l'Association des anatomistes, 1997- |
| مواضيع طبية MeSH: | Homeodomain Proteins*/metabolism , Homeodomain Proteins*/genetics , Cartilage*/metabolism , Cartilage*/embryology, Animals ; Chick Embryo ; Chickens/metabolism ; Chickens/genetics ; Jaw/embryology ; Jaw/metabolism ; Branchial Region/metabolism ; Branchial Region/embryology ; Muscle Development ; Gene Expression Regulation, Developmental ; Immunohistochemistry ; Muscle, Skeletal/metabolism ; Muscle, Skeletal/embryology |
| مستخلص: | Objective: To elucidate the branchial origin of the articular and the square (homology of the malleus and the incus of mammals), we used immunohistochemistry to analyse the expression of the Hox-A2 protein during cephalogenesis in chickens. Materials and Methods: Immunohistochemistry on paraffin sections of embryos from stage HH16 to HH40. Results: In addition to the columella (equivalent to the mammalian stapes), the joint between the articular and the quadrate bones, and the retro-articular process of the articular (homologous to the short process of the malleus) express Hox-A2, suggesting an intervention of the 2nd arch in their formation. However, we fortuitously observed very intense expression within the early muscle plate of the second arch, which then generalized to all cephalic muscles, and extended to the trunk's myotomes. In the cartilage, the presence of the protein disappeared at stage 35. Discussion and Conclusion: The present results, while confirming the contribution of the second arch to the development of avian equivalents of the mammalian ear ossicles, strongly suggest that the Hox-A2 gene plays a role in muscle development, which remains to be elucidated by more sophisticated techniques. (Copyright © 2024 Elsevier Masson SAS. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Cephalic cartilages; Chick embryo; Hox-A2; Muscles |
| المشرفين على المادة: | 0 (Homeodomain Proteins) |
| تواريخ الأحداث: | Date Created: 20240412 Date Completed: 20240828 Latest Revision: 20240829 |
| رمز التحديث: | 20240831 |
| DOI: | 10.1016/j.morpho.2024.100780 |
| PMID: | 38608627 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1286-0115 |
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| DOI: | 10.1016/j.morpho.2024.100780 |