دورية أكاديمية
The Circulating Selenium Concentration Is Positively Related to the Lipid Accumulation Product: A Population-Based Cross-Sectional Study.
| العنوان: | The Circulating Selenium Concentration Is Positively Related to the Lipid Accumulation Product: A Population-Based Cross-Sectional Study. |
|---|---|
| المؤلفون: | Zhao K; National Key Laboratory for Innovation and Transformation of Luobing Theory, The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences; Department of Cardiology, Qilu Hospital of Shandong University, Jinan 250012, China., Zhang Y; National Key Laboratory for Innovation and Transformation of Luobing Theory, The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences; Department of Cardiology, Qilu Hospital of Shandong University, Jinan 250012, China., Sui W; National Key Laboratory for Innovation and Transformation of Luobing Theory, The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences; Department of Cardiology, Qilu Hospital of Shandong University, Jinan 250012, China. |
| المصدر: | Nutrients [Nutrients] 2024 Mar 23; Vol. 16 (7). Date of Electronic Publication: 2024 Mar 23. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: MDPI Publishing Country of Publication: Switzerland NLM ID: 101521595 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6643 (Electronic) Linking ISSN: 20726643 NLM ISO Abbreviation: Nutrients Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Basel, Switzerland : MDPI Publishing |
| مواضيع طبية MeSH: | Selenium* , Lipid Accumulation Product* , Metabolic Syndrome*/epidemiology, Adult ; Male ; Humans ; Cross-Sectional Studies ; Obesity |
| مستخلص: | The lipid accumulation product (LAP) is a reliable marker of metabolic syndrome, which includes conditions like obesity. However, the correlation between the circulating selenium (CSe) concentration and the LAP is currently unclear. This study aimed to ascertain this correlation. Overall, 12,815 adults aged ≥20 years were enrolled in this study. After adjusting for all the confounding variables, CSe was positively correlated to the LAP (β = 0.41; 95% confidence interval [CI]: 0.28, 0.54; p < 0.001). Compared with the lowest quartile of CSe, the highest quartile of CSe was positively related to the LAP (β = 0.16; 95% CI: 0.12, 0.21; p < 0.001). Moreover, the correlation between CSe and the LAP revealed a positive non-linear trend. In the subgroup analysis, interaction effects were observed for age, sex, smoking, and stroke ( p for interaction < 0.05). The effects were stronger for males (β = 0.64, 95% CI: 0.47, 0.80; p < 0.001) and individuals who smoke at the time of the trial (β = 0.64, 95% CI: 0.37, 0.91; p < 0.001). In conclusion, our results indicated that CSe was positively correlated with the LAP in a non-linear manner. Future research is warranted to explore their relationship and better understand the mechanisms underlying this association. |
| References: | J Clin Epidemiol. 2004 Oct;57(10):1096-103. (PMID: 15528061) Front Nutr. 2022 Aug 16;9:970206. (PMID: 36051904) Eur Heart J. 2020 Jan 7;41(2):255-323. (PMID: 31497854) BMC Cardiovasc Disord. 2005 Sep 08;5:26. (PMID: 16150143) Vital Health Stat 2. 2013 Sep;(161):1-24. (PMID: 25090154) N Engl J Med. 1999 Aug 5;341(6):427-34. (PMID: 10432328) J Atheroscler Thromb. 2014;21(3):282-8. (PMID: 24304961) J Trace Elem Med Biol. 2000 Apr;14(1):1-5. (PMID: 10836527) Clin Nutr. 2022 Apr;41(4):862-884. (PMID: 35276570) BMJ Open Diabetes Res Care. 2016 Aug 12;4(1):e000253. (PMID: 27547419) Int J Obes (Lond). 2015 Feb;39(2):189-98. (PMID: 24909829) JAMA. 2017 Aug 15;318(7):603. (PMID: 28810033) Nutr Metab Cardiovasc Dis. 2022 Nov;32(11):2568-2578. (PMID: 36155151) Metabolites. 2023 Feb 03;13(2):. (PMID: 36837846) Arch Biochem Biophys. 2016 Apr 1;595:113-9. (PMID: 27095226) Cureus. 2023 Mar 4;15(3):e35771. (PMID: 37020489) Biol Trace Elem Res. 2024 Jan;202(1):25-33. (PMID: 37004705) Front Nutr. 2023 Mar 13;10:1098761. (PMID: 36992905) Nutrients. 2021 Sep 17;13(9):. (PMID: 34579115) Eur J Endocrinol. 2023 Mar 2;188(3):R37-R45. (PMID: 36883605) Arch Intern Med. 2001 Jul 9;161(13):1581-6. (PMID: 11434789) Oxid Med Cell Longev. 2017;2017:7478523. (PMID: 29441149) Lancet. 2006 Aug 19;368(9536):666-78. (PMID: 16920472) Int J Mol Sci. 2023 Jan 24;24(3):. (PMID: 36768633) Arch Biochem Biophys. 2022 Nov 30;731:109445. (PMID: 36265651) Sci Rep. 2017 Apr 3;7(1):550. (PMID: 28373703) Front Nutr. 2023 Feb 28;10:1048230. (PMID: 36925956) Eur Heart J. 2007 Aug;28(16):2043-4. (PMID: 17567621) Metallomics. 2017 Jan 25;9(1):21-37. (PMID: 28009916) Cancers (Basel). 2023 Feb 03;15(3):. (PMID: 36765934) Curr Protein Pept Sci. 2014;15(6):598-607. (PMID: 24910086) Eur J Clin Nutr. 2005 Oct;59(10):1181-90. (PMID: 16034362) J Nutr Biochem. 2023 Mar;113:109230. (PMID: 36435293) Mult Scler Relat Disord. 2023 Apr;72:104605. (PMID: 36907120) Antioxidants (Basel). 2022 Dec 10;11(12):. (PMID: 36552647) JAMA Intern Med. 2020 Mar 1;180(3):367-374. (PMID: 31886824) Lancet. 2005 Nov 5;366(9497):1640-9. (PMID: 16271645) PeerJ. 2020 May 04;8:e9127. (PMID: 32411541) Microbiology (Reading). 2010 Sep;156(Pt 9):2608-2620. (PMID: 20522499) J Trace Elem Med Biol. 2003;17(1):13-8. (PMID: 12755496) Biol Trace Elem Res. 2016 Nov;174(1):32-39. (PMID: 27075547) Lancet. 2011 Aug 27;378(9793):804-14. (PMID: 21872749) Lancet. 2012 Mar 31;379(9822):1256-68. (PMID: 22381456) Hum Genet. 2007 Nov;122(3-4):355-65. (PMID: 17641917) Am J Clin Nutr. 1990 Nov;52(5):858-62. (PMID: 2239761) Int J Endocrinol. 2020 May 28;2020:4802739. (PMID: 32565792) Diabetes Care. 2006 Jan;29(1):151-3. (PMID: 16373916) |
| معلومات مُعتمدة: | 82000411 National Natural Science Foundation of China; 82030051 National Natural Science Foundation of China; 2021YFF0501403 National Key R & D Program of China; ZR2020QH023 Key R & D Program of Shandong Province; 2021SFGC0503 Key R & D Program of Shandong Province; 2021ZDSYS05 Key R & D Program of Shandong Province; 2020ZLYS05 Key R & D Program of Shandong Province |
| فهرسة مساهمة: | Keywords: lipid accumulation product; obesity; selenium |
| المشرفين على المادة: | H6241UJ22B (Selenium) |
| تواريخ الأحداث: | Date Created: 20240413 Date Completed: 20240415 Latest Revision: 20240425 |
| رمز التحديث: | 20240425 |
| مُعرف محوري في PubMed: | PMC11013112 |
| DOI: | 10.3390/nu16070933 |
| PMID: | 38612965 |
| قاعدة البيانات: | MEDLINE |
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