Left ventricular concentric remodeling in COPD patients: A cross-sectional observational study.

التفاصيل البيبلوغرافية
العنوان:	Left ventricular concentric remodeling in COPD patients: A cross-sectional observational study.
المؤلفون:	Tais Leonardi N; Department of Physical Therapy, Federal University of Sao Carlos, Rodovia Washington Luís, Km 235, Jardim Guanabara, 13565-905 São Carlos, São Paulo, Brazil., da Silva Rocha Tomaz C; Department of Physical Therapy, Federal University of Sao Carlos, Rodovia Washington Luís, Km 235, Jardim Guanabara, 13565-905 São Carlos, São Paulo, Brazil., Zavaglia Kabbach E; Department of Physical Therapy, Federal University of Sao Carlos, Rodovia Washington Luís, Km 235, Jardim Guanabara, 13565-905 São Carlos, São Paulo, Brazil., Domingues Heubel A; Department of Physical Therapy, Federal University of Sao Carlos, Rodovia Washington Luís, Km 235, Jardim Guanabara, 13565-905 São Carlos, São Paulo, Brazil., Souza Schafauser N; Department of Physical Therapy, Federal University of Sao Carlos, Rodovia Washington Luís, Km 235, Jardim Guanabara, 13565-905 São Carlos, São Paulo, Brazil., Mayumi de Oliveira Kawakami D; Department of Physical Therapy, Federal University of Sao Carlos, Rodovia Washington Luís, Km 235, Jardim Guanabara, 13565-905 São Carlos, São Paulo, Brazil., Borghi-Silva A; Department of Physical Therapy, Federal University of Sao Carlos, Rodovia Washington Luís, Km 235, Jardim Guanabara, 13565-905 São Carlos, São Paulo, Brazil., Goi Roscani M; Department of Medicine, Federal University of Sao Carlos (UFSCar), Rodovia Washington Luís, Km 235, Jardim Guanabara, 13565-905 São Carlos, São Paulo, Brazil., Castello-Simões V; Department of Physical Therapy, Federal University of Sao Carlos, Rodovia Washington Luís, Km 235, Jardim Guanabara, 13565-905 São Carlos, São Paulo, Brazil., Gonçalves Mendes R; Department of Physical Therapy, Federal University of Sao Carlos, Rodovia Washington Luís, Km 235, Jardim Guanabara, 13565-905 São Carlos, São Paulo, Brazil. Electronic address: renatamendes@ufscar.br.
المصدر:	Medicina clinica [Med Clin (Barc)] 2024 Jul 12; Vol. 163 (1), pp. 8-13. Date of Electronic Publication: 2024 Apr 12.
نوع المنشور:	Journal Article; Observational Study; Research Support, Non-U.S. Gov't
اللغة:	English; Spanish; Castilian
بيانات الدورية:	Publisher: Elsevier España Country of Publication: Spain NLM ID: 0376377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1578-8989 (Electronic) Linking ISSN: 00257753 NLM ISO Abbreviation: Med Clin (Barc) Subsets: MEDLINE
أسماء مطبوعة:	Publication: <2009- > : Madrid : Elsevier España Original Publication: Barcelona : Ediciones Doyma, S.A.
مواضيع طبية MeSH:	Pulmonary Disease, Chronic Obstructive/physiopathology , Ventricular Remodeling , Severity of Illness Index*, Humans ; Male ; Cross-Sectional Studies ; Female ; Aged ; Middle Aged ; Echocardiography ; Forced Expiratory Volume ; Walk Test ; Body Mass Index
مستخلص:	Objective: To investigate the association between left ventricular structure and disease severity in COPD patients. Methods: Twenty-eight COPD patients were stratified according to the disease severity, using the BODE index, into L ower (n=17) and H igher (n=11) groups, composed of patients with lower severity (BODE <5) and higher severity (BODE ≥5), respectively. Left ventricle (LV) was assessed by 2D-echocardiography. BODE index was calculated using body mass index (BMI); forced expiratory volume in the first second (FEV 1 , %); modified Medical Research Council (mMRC) and distance walked during 6-minute walk test (6MWD). Results: Patients in the H igher group showed lower oxygen arterial saturation (p=0.02), FEV 1 (p<0.01) and 6MWD (p=0.02) and higher value of relative posterior wall thickness (RWT) compared to L ower group (p=0.02). There were significant associations between LV end-systolic diameter (LVESD) and BODE index (r=-0.38, p=0.04), LV end-diastolic diameter (LVEDD) and FEV 1 (r=0.44, p=0.02), LVEDD and BMI (r=0.45, p=0.02), LVESD and BMI (r=0.54, p=0.003) and interventricular septal thickness and 6MWD (r=-0.39, p=0.04). Conclusions: More severe COPD patients, BODE score ≥5, may have higher RWT, featuring a possible higher concentric remodeling of LV in this group. Besides that, a greater disease severity may be related to LV chamber size reduction. (Copyright © 2024 Elsevier España, S.L.U. All rights reserved.)
فهرسة مساهمة:	Keywords: BODE index; Chronic obstructive pulmonary disease; Enfermedad pulmonar obstructiva crónica; Left ventricle; Remodelación ventricular; Ventricular remodeling; Ventrículo izquierdo; Índice BODE
تواريخ الأحداث:	Date Created: 20240413 Date Completed: 20240701 Latest Revision: 20240828
رمز التحديث:	20240830
DOI:	10.1016/j.medcli.2024.01.024
PMID:	38614905
قاعدة البيانات:	MEDLINE

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تدمد:	1578-8989
DOI:	10.1016/j.medcli.2024.01.024