دورية أكاديمية
Multi-center study on mortality in children, and adults with sickle cell anemia-risk factors and causes of death.
| العنوان: | Multi-center study on mortality in children, and adults with sickle cell anemia-risk factors and causes of death. |
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| المؤلفون: | Alkindi S; Department of Haematology, College of Medicine and Health Sciences, Sultan Qaboos University, P. O. Box 35, 123, Muscat, Oman. sskindi@yahoo.com., Al-Jadidi S; Department of Haematology, College of Medicine and Health Sciences, Sultan Qaboos University, P. O. Box 35, 123, Muscat, Oman., Al-Adawi S; Department of Haematology, College of Medicine and Health Sciences, Sultan Qaboos University, P. O. Box 35, 123, Muscat, Oman., Elsadek RA; Department of Medicine, Nizwa Hospital, Nizwa, Oman., Al Madhani A; Department of Medicine, Sohar Hospital, Sohar, Oman., Al-Nabhani M; Emergency Department, Royal Hospital, Muscat, Oman., Pathare AV; Department of Haematology, College of Medicine and Health Sciences, Sultan Qaboos University, P. O. Box 35, 123, Muscat, Oman. |
| المصدر: | Scientific reports [Sci Rep] 2024 Apr 13; Vol. 14 (1), pp. 8584. Date of Electronic Publication: 2024 Apr 13. |
| نوع المنشور: | Multicenter Study; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: London : Nature Publishing Group, copyright 2011- |
| مواضيع طبية MeSH: | Acute Chest Syndrome*/etiology , Anemia, Sickle Cell*/complications, Adult ; Female ; Humans ; Male ; Young Adult ; Anti-Bacterial Agents ; Causality ; Cause of Death ; Risk Factors |
| مستخلص: | Sickle cell disease (SCD) is a major public health burden worldwide with increasing morbidity and mortality. The study evaluates the risk factors associated with mortality in SCD patients, between the years 2006 and 2020 at three hospitals in Oman. The analysis includes clinical manifestations, haematological, biochemical, and radiological parameters, use of antibiotics, and blood and exchange transfusions. Our cohort included 123 patients (82 males, 41 females), with a median age of 27 (Interquartile Range 21-35 years). SCD related complications included acute chest syndrome (ACS) in 52.8%, splenic sequestration in 21.1%, right upper quadrant syndrome in 19.5%, more than > 6 VOC/year in 17.9%, and stroke in 13.8%. At the terminal admission, patients had cough, reduced O (© 2024. The Author(s).) |
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| فهرسة مساهمة: | Keywords: Acute chest syndrome; Predictors of mortality; SCD; Sepsis; Sickle cell disease; Sudden death |
| المشرفين على المادة: | 0 (Anti-Bacterial Agents) |
| تواريخ الأحداث: | Date Created: 20240413 Date Completed: 20240415 Latest Revision: 20240430 |
| رمز التحديث: | 20240501 |
| مُعرف محوري في PubMed: | PMC11016086 |
| DOI: | 10.1038/s41598-024-58328-9 |
| PMID: | 38615021 |
| قاعدة البيانات: | MEDLINE |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 2045-2322 |
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| DOI: | 10.1038/s41598-024-58328-9 |