دورية أكاديمية
Phenotypic and genotypic antimicrobial resistance of Listeria spp. in Spain.
| العنوان: | Phenotypic and genotypic antimicrobial resistance of Listeria spp. in Spain. |
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| المؤلفون: | Markovich Y; Research Group Intracellular Pathogens: Biology and Infection, Departamento Producción y Sanidad Animal, Salud Pública Veterinaria y Ciencia y Tecnología de los Alimentos, Facultad de Veterinaria, Universidad Cardenal Herrera-CEU, CEU Universities, Carrer Tirant lo Blanc, 7, Alfara del Patriarca, Valencia 46115, Spain. Electronic address: yuval.markovich@uchceu.es., Palacios-Gorba C; Research Group Intracellular Pathogens: Biology and Infection, Departamento Producción y Sanidad Animal, Salud Pública Veterinaria y Ciencia y Tecnología de los Alimentos, Facultad de Veterinaria, Universidad Cardenal Herrera-CEU, CEU Universities, Carrer Tirant lo Blanc, 7, Alfara del Patriarca, Valencia 46115, Spain. Electronic address: carla.palaciosgorba@uchceu.es., Gomis J; Research Group Microbiological Agents Associated with Animal Reproduction (ProVaginBIO), Departamento Producción y Sanidad Animal, Salud Pública Veterinaria y Ciencia y Tecnología de los Alimentos, Facultad de Veterinaria, Universidad Cardenal Herrera-CEU, CEU Universities, Carrer Tirant lo Blanc, 7 Alfara del Patriarca, Valencia 46115, Spain. Electronic address: jesus.gomis1@uchceu.es., Gómez-Martín Á; Research Group Microbiological Agents Associated with Animal Reproduction (ProVaginBIO), Departamento Producción y Sanidad Animal, Salud Pública Veterinaria y Ciencia y Tecnología de los Alimentos, Facultad de Veterinaria, Universidad Cardenal Herrera-CEU, CEU Universities, Carrer Tirant lo Blanc, 7 Alfara del Patriarca, Valencia 46115, Spain. Electronic address: angel.gomezmartin@uchceu.es., Ortolá S; Public Health Laboratory of Valencia, 21, Avenida Catalunya, Valencia 46020, Spain. Electronic address: ortola_sus@gva.es., Quereda JJ; Research Group Intracellular Pathogens: Biology and Infection, Departamento Producción y Sanidad Animal, Salud Pública Veterinaria y Ciencia y Tecnología de los Alimentos, Facultad de Veterinaria, Universidad Cardenal Herrera-CEU, CEU Universities, Carrer Tirant lo Blanc, 7, Alfara del Patriarca, Valencia 46115, Spain. Electronic address: juan.quereda@uchceu.es. |
| المصدر: | Veterinary microbiology [Vet Microbiol] 2024 Jun; Vol. 293, pp. 110086. Date of Electronic Publication: 2024 Apr 06. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Scientific Pub. Co Country of Publication: Netherlands NLM ID: 7705469 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2542 (Electronic) Linking ISSN: 03781135 NLM ISO Abbreviation: Vet Microbiol Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Amsterdam, Elsevier Scientific Pub. Co. |
| مواضيع طبية MeSH: | Listeria*/drug effects , Listeria*/genetics , Listeria*/classification , Listeria*/isolation & purification , Anti-Bacterial Agents*/pharmacology , Microbial Sensitivity Tests* , Listeriosis*/microbiology , Listeriosis*/veterinary , Listeriosis*/epidemiology, Animals ; Spain/epidemiology ; Genotype ; Drug Resistance, Bacterial/genetics ; Whole Genome Sequencing ; Listeria monocytogenes/drug effects ; Listeria monocytogenes/genetics ; Listeria monocytogenes/isolation & purification ; Humans ; Phenotype |
| مستخلص: | Listeriosis is a zoonotic disease caused by Listeria monocytogenes and Listeria ivanovii. The genus Listeria currently includes 27 recognized species and is found throughout the environment. The number of systematic studies on antimicrobial resistance in L. monocytogenes isolates from domestic farms using antimicrobial substances is limited. Importantly, dairy ruminant farms are reservoir of hypervirulent lineage I L. monocytogenes isolates, previously associated with human clinical cases. Considering that the classes of antibiotics used in food-producing domestic animals are frequently the same or closely related to those used in human medicine, studies about the impact of antibiotic use on the acquisition of antibiotic resistance in Listeria spp. in domestic animal farms are, therefore, of high importance. Here, susceptibility to 25 antibiotics was determined. Eighty-one animal-related, 35 food and 21 human pathogenic Listeria spp. isolates and 114 animal-related non-pathogenic Listeria spp. isolates were tested. Whole genome sequencing data was used for molecular characterization. Regarding L. monocytogenes, 2 strains from the clinical-associated linage I showed resistance to erythromycin, both related to dairy ruminants. Acquired resistance to one antibiotic was exhibited in 1.5% of L. monocytogenes isolates compared with 14% of non-pathogenic Listeria spp. isolates. Resistance to tetracycline (7.9%), doxycycline (7.9%), penicillin (4.4%), and ampicillin (4.4%) were the most frequently observed in non-pathogenic Listeria spp. While resistance to two or more antibiotics (5.6%) was most common in Listeria spp., isolates, resistance to one antibiotic was also observed (1.6%). The present results show that non-pathogenic Listeria spp. harbour antimicrobial resistance genes. Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (Copyright © 2024. Published by Elsevier B.V.) |
| فهرسة مساهمة: | Keywords: Antibiotic pressure; Listeria spp.; Resistance genes; WGS |
| المشرفين على المادة: | 0 (Anti-Bacterial Agents) |
| تواريخ الأحداث: | Date Created: 20240414 Date Completed: 20240513 Latest Revision: 20240513 |
| رمز التحديث: | 20240514 |
| DOI: | 10.1016/j.vetmic.2024.110086 |
| PMID: | 38615477 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1873-2542 |
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| DOI: | 10.1016/j.vetmic.2024.110086 |