دورية أكاديمية
Plasma Sphingomyelins and Carnitine Esters of Infants Consuming Whole Goat or Cow Milk-Based Infant Formulas or Human Milk.
| العنوان: | Plasma Sphingomyelins and Carnitine Esters of Infants Consuming Whole Goat or Cow Milk-Based Infant Formulas or Human Milk. |
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| المؤلفون: | Demmelmair H; Department of Pediatrics, Division of Metabolic and Nutritional Medicine, Ludwig Maximilians University Munich, Dr. von Hauner Children's Hospital, Munich, Germany. Electronic address: hans.demmelmair@med.uni-muenchen.de., Uhl O; Department of Pediatrics, Division of Metabolic and Nutritional Medicine, Ludwig Maximilians University Munich, Dr. von Hauner Children's Hospital, Munich, Germany., Zhou SJ; Food and Wine, School of Agriculture, University of Adelaide, Adelaide, Australia., Makrides M; Woman's and Children's Health Research Institute, University of Adelaide, Adelaide, Australia., Gibson RA; Food and Wine, School of Agriculture, University of Adelaide, Adelaide, Australia., Prosser C; Science Department, Dairy Goat Co-operative (NZ) Ltd, Hamilton, New Zealand., Gallier S; Science Department, Dairy Goat Co-operative (NZ) Ltd, Hamilton, New Zealand., Koletzko B; Department of Pediatrics, Division of Metabolic and Nutritional Medicine, Ludwig Maximilians University Munich, Dr. von Hauner Children's Hospital, Munich, Germany. |
| المصدر: | The Journal of nutrition [J Nutr] 2024 Jun; Vol. 154 (6), pp. 1781-1789. Date of Electronic Publication: 2024 Apr 12. |
| نوع المنشور: | Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: United States NLM ID: 0404243 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1541-6100 (Electronic) Linking ISSN: 00223166 NLM ISO Abbreviation: J Nutr Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2023- : [New York, NY] : Elsevier Original Publication: 1928-1933 : Springfield, Ill. : C. C. Thomas |
| مواضيع طبية MeSH: | Infant Formula*/chemistry , Carnitine*/blood , Carnitine*/analogs & derivatives , Goats* , Milk, Human*/chemistry , Sphingomyelins*/blood , Milk*/chemistry, Humans ; Animals ; Infant ; Female ; Male ; Cattle ; Breast Feeding ; Esters/blood ; Infant, Newborn ; Plant Oils/chemistry |
| مستخلص: | Background: Infant formulas are typically manufactured using skimmed milk, whey proteins, and vegetable oils, which excludes milk fat globule membranes (MFGM). MFGM contains polar lipids, including sphingomyelin (SM). Objective: The objective of this study was comparison of infant plasma SM and acylcarnitine species between infants who are breastfed or receiving infant formulas with different fat sources. Methods: In this explorative study, we focused on SM and acylcarnitine species concentrations measured in plasma samples from the TIGGA study (ACTRN12608000047392), where infants were randomly assigned to receive either a cow milk-based infant formula (CIF) with vegetable oils only or a goat milk-based infant formula (GIF) with a goat milk fat (including MFGM) and vegetable oil mixture to the age ≥4 mo. Breastfed infants were followed as a reference group. Using tandem mass spectrometry, SM species in the study formulas and SM and acylcarnitine species in plasma samples collected at the age of 4 mo were analyzed. Results: Total SM concentrations (∼42 μmol/L) and patterns of SM species were similar in both formulas. The total plasma SM concentrations were not different between the formula groups but were 15 % (CIF) and 21% (GIF) lower in the formula groups than in the breastfed group. Between the formula groups, differences in SM species were statistically significant but small. Total carnitine and major (acyl) carnitine species were not different between the groups. Conclusions: The higher total SM concentration in breastfed than in formula-fed infants might be related to a higher SM content in human milk, differences in cholesterol metabolism, dietary fatty acid intake, or other factors not yet identified. SM and acylcarnitine species composition in plasma is not closely related to the formula fatty acid composition. This trial was registered at Australian New Zealand Clinical Trials Registry as ACTRN12608000047392. (Copyright © 2024 The Author(s). Published by Elsevier Inc. All rights reserved.) |
| References: | Acta Paediatr. 2015 Dec;104(467):14-9. (PMID: 26211556) Nutr Res Rev. 1998 Dec;11(2):255-78. (PMID: 19094250) Nutr Diabetes. 2014 Oct 20;4:e141. (PMID: 25329603) Curr Nutr Rep. 2022 Jun;11(2):283-300. (PMID: 35334102) Br J Nutr. 2014 May;111(9):1641-51. (PMID: 24502951) Dtsch Arztebl Int. 2016 Jun 24;113(25):435-44. (PMID: 27397020) Appl Environ Microbiol. 2013 May;79(9):3040-8. (PMID: 23455335) PLoS One. 2015 Dec 30;10(12):e0145794. (PMID: 26716698) PLoS One. 2013 Dec 16;8(12):e82459. (PMID: 24358186) Sci Rep. 2019 Oct 4;9(1):14321. (PMID: 31586083) Brain Dev. 2013 Jan;35(1):45-52. (PMID: 22633446) J Pediatr. 2016 Jun;173 Suppl:S53-9. (PMID: 27234412) PLoS One. 2016 Aug 29;11(8):e0162040. (PMID: 27571269) Elife. 2022 Mar 02;11:. (PMID: 35234611) Lipids Health Dis. 2019 Jan 22;18(1):20. (PMID: 30670033) J Pediatr Gastroenterol Nutr. 2015 Sep;61(3):367-72. (PMID: 25782660) Lipids. 2006 Sep;41(9):851-8. (PMID: 17152922) Br J Nutr. 2007 Oct;98 Suppl 1:S68-73. (PMID: 17922964) J Lipid Res. 2006 Jan;47(1):154-71. (PMID: 16251722) Diabetes. 2013 Jan;62(1):1-8. (PMID: 23258903) Pediatr Res. 2018 Nov;84(5):726-732. (PMID: 30120403) J Agric Food Chem. 2023 Jun 7;71(22):8633-8647. (PMID: 37232935) Early Hum Dev. 2012 Aug;88(8):595-601. (PMID: 22289412) J Nutr. 1999 Jul;129(7):1239-50. (PMID: 10395583) Nat Rev Endocrinol. 2017 Feb;13(2):79-91. (PMID: 27767036) PLoS One. 2017 Nov 2;12(11):e0187136. (PMID: 29095868) Rev Endocr Metab Disord. 2018 Mar;19(1):93-106. (PMID: 29926323) FASEB J. 2017 Apr;31(4):1263-1272. (PMID: 28003342) J Agric Food Chem. 2019 Dec 18;67(50):13922-13928. (PMID: 31746600) Pharmacol Rev. 2022 Jul;74(3):506-551. (PMID: 35710135) Pediatr Res. 2014 Oct;76(4):394-400. (PMID: 25116230) J Pediatr Gastroenterol Nutr. 2015 Jul;61(1):8-17. (PMID: 25883056) J Pediatr. 2015 Feb;166(2):276-81.e6. (PMID: 25454937) Front Nutr. 2023 Aug 30;10:1227340. (PMID: 37712002) Sci Rep. 2019 Jan 23;9(1):339. (PMID: 30674917) J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Jan 1;1072:235-243. (PMID: 29195142) J Pediatr Gastroenterol Nutr. 2000 Feb;30(2):115-30. (PMID: 10697128) J Lipid Res. 2009 Mar;50(3):574-585. (PMID: 18832345) Antioxidants (Basel). 2023 Jan 06;12(1):. (PMID: 36671005) Mediators Inflamm. 2015;2015:520618. (PMID: 26648664) Clin Nutr. 2022 Aug;41(8):1735-1745. (PMID: 35779425) J Agric Food Chem. 2021 Feb 17;69(6):1831-1841. (PMID: 33538162) Food Chem. 2023 Jul 30;415:135762. (PMID: 36870206) J Pediatr Gastroenterol Nutr. 2015 Mar;60(3):384-9. (PMID: 25714582) Early Hum Dev. 1998 Dec;53 Suppl:S149-64. (PMID: 10102662) Lipids. 1999 Dec;34(12):1243-71. (PMID: 10652985) J Clin Endocrinol Metab. 2015 Jan;100(1):149-58. (PMID: 25368978) Br J Nutr. 2000 May;83(5):541-7. (PMID: 10953679) Nutrients. 2020 Nov 13;12(11):. (PMID: 33202897) Sci Rep. 2017 Jun 21;7(1):3975. (PMID: 28638093) Aging Cell. 2015 Feb;14(1):112-21. (PMID: 25345489) J Pediatr. 2016 Jun;173 Suppl:S60-5. (PMID: 27234413) Adv Nutr. 2022 Mar;13(2):474-491. (PMID: 34549256) PLoS One. 2013 Apr 09;8(4):e61369. (PMID: 23585895) Eur J Clin Nutr. 2008 Feb;62(2):203-9. (PMID: 17327867) Food Chem. 2022 Sep 15;388:132939. (PMID: 35447582) J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Oct 1;857(2):251-8. (PMID: 17692580) Lancet. 2016 Jan 30;387(10017):475-90. (PMID: 26869575) Nutrients. 2020 Jul 21;12(7):. (PMID: 32708300) Am J Clin Nutr. 2014 Apr;99(4):860-8. (PMID: 24500150) J Pediatr Gastroenterol Nutr. 2011 Nov;53(5):561-8. (PMID: 21637131) Nat Rev Mol Cell Biol. 2018 Mar;19(3):175-191. (PMID: 29165427) J Lipid Res. 1993 Aug;34(8):1403-11. (PMID: 8409771) |
| فهرسة مساهمة: | Keywords: acylcarnitines; breastfeeding; goat milk; infant formula; sphingomyelins; vegetable oil |
| المشرفين على المادة: | S7UI8SM58A (Carnitine) 0 (Sphingomyelins) 0 (acylcarnitine) 0 (Esters) 0 (Plant Oils) |
| تواريخ الأحداث: | Date Created: 20240414 Date Completed: 20240606 Latest Revision: 20240722 |
| رمز التحديث: | 20240723 |
| مُعرف محوري في PubMed: | PMC11217027 |
| DOI: | 10.1016/j.tjnut.2024.04.020 |
| PMID: | 38615734 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1541-6100 |
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| DOI: | 10.1016/j.tjnut.2024.04.020 |