دورية أكاديمية

Sexual dysfunction among Nigerian women living with HIV infection.

التفاصيل البيبلوغرافية
العنوان: Sexual dysfunction among Nigerian women living with HIV infection.
المؤلفون: Ezechi OC; Center for Reproduction and Population Health Studies, Clinical Sciences Department, Nigerian Institute of Medical Research, Yaba, Lagos State, Nigeria.; Department of Public Health, Faculty of Basic Medical and Health Sciences, Lead City University, Ibadan, Oyo State, Nigeria., Akinsolu FT; Center for Reproduction and Population Health Studies, Clinical Sciences Department, Nigerian Institute of Medical Research, Yaba, Lagos State, Nigeria.; Department of Public Health, Faculty of Basic Medical and Health Sciences, Lead City University, Ibadan, Oyo State, Nigeria., Gbajabiamila TA; Center for Reproduction and Population Health Studies, Clinical Sciences Department, Nigerian Institute of Medical Research, Yaba, Lagos State, Nigeria., Idigbe IE; Center for Reproduction and Population Health Studies, Clinical Sciences Department, Nigerian Institute of Medical Research, Yaba, Lagos State, Nigeria., Ezeobi PM; Center for Reproduction and Population Health Studies, Clinical Sciences Department, Nigerian Institute of Medical Research, Yaba, Lagos State, Nigeria.; Department of Public Health, Faculty of Basic Medical and Health Sciences, Lead City University, Ibadan, Oyo State, Nigeria., Musa AZ; Center for Reproduction and Population Health Studies, Clinical Sciences Department, Nigerian Institute of Medical Research, Yaba, Lagos State, Nigeria.; Department of Public Health, Faculty of Basic Medical and Health Sciences, Lead City University, Ibadan, Oyo State, Nigeria., Wapmuk AE; Center for Reproduction and Population Health Studies, Clinical Sciences Department, Nigerian Institute of Medical Research, Yaba, Lagos State, Nigeria.
المصدر: PloS one [PLoS One] 2024 Apr 18; Vol. 19 (4), pp. e0292294. Date of Electronic Publication: 2024 Apr 18 (Print Publication: 2024).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
أسماء مطبوعة: Original Publication: San Francisco, CA : Public Library of Science
مواضيع طبية MeSH: HIV Infections*/complications , HIV Infections*/epidemiology , Sexual Dysfunctions, Psychological*/epidemiology , Sexual Dysfunctions, Psychological*/etiology , Sexual Dysfunction, Physiological*/etiology , Sexual Dysfunction, Physiological*/complications, Adult ; Humans ; Female ; Cross-Sectional Studies ; Surveys and Questionnaires ; Nigeria/epidemiology ; Protease Inhibitors
مستخلص: Introduction: Sexual dysfunction in women with HIV is a necessary but understudied aspect of HIV complications in women living with HIV. This study reports the prevalence, pattern, and risk factors for sexual dysfunction in women living with HIV in southwest Nigeria.
Methods: A validated Female Sexual Function Index was used to determine sexual dysfunction in a cross-sectional study design involving 2926 adult women living with HIV in a large, publicly funded tertiary HIV treatment centre in Lagos, Nigeria. A score of less than 26.5 indicated sexual dysfunction. Multivariate logistic regression analysis was performed to identify risk factors for sexual dysfunction. P<0.05 was considered statistically significant at a 95% confidence interval (CI).
Results: The prevalence of sexual dysfunction was 71.4%. The types of dysfunctions detected included disorder of desire (76.8%), sexual arousal (66.0%), orgasm (50.0%), pain (47.2%), lubrication (47.2%), and satisfaction (38.8%). Multivariate analysis showed that menopause (aOR: 2.0; 1.4-4.1), PHQ score of 10 and above (aOR: 2.3; 1.7-3.2), co-morbid medical conditions (aOR: 1.8; 1.4-2.7), use of protease inhibitor-based antiretroviral therapy (aOR: 1.3; 1.2-2.1) and non-disclosure of HIV status (aOR: 0.7; 0.6-0.8) were factors associated with sexual dysfunction.
Conclusions: Sexual dysfunction is common among Nigerian women living with HIV. Menopause, use of protease inhibitor-based regimens, PHQ score of at least 10, co-morbid medical condition, and non-disclosure of HIV status were associated with sexual dysfunction. National HIV programmes, in addition to incorporating screening and management of sexual dysfunction in the guidelines, should sensitise and train health workers on the detection and treatment of sexual dysfunction.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright: © 2024 Ezechi et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
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المشرفين على المادة: 0 (Protease Inhibitors)
تواريخ الأحداث: Date Created: 20240418 Date Completed: 20240422 Latest Revision: 20240425
رمز التحديث: 20240425
مُعرف محوري في PubMed: PMC11025868
DOI: 10.1371/journal.pone.0292294
PMID: 38635555
قاعدة البيانات: MEDLINE
الوصف
تدمد:1932-6203
DOI:10.1371/journal.pone.0292294