دورية أكاديمية

Vitamin D 3 among neonates born after in vitro fertilization compared with neonates from the general population.

التفاصيل البيبلوغرافية
العنوان: Vitamin D 3 among neonates born after in vitro fertilization compared with neonates from the general population.
المؤلفون: Walker KC; Research Unit for Dietary Studies, The Parker Institute, Bispebjerg and Frederiksberg Hospital, Frederiksberg, Denmark., Pristed SG; Department of Obstetrics and Gynecology, Aalborg University Hospital, Aalborg, Denmark.; Program of Biomedical Laboratory Science, University College of Northern Denmark, Aalborg, Denmark., Thorsteinsdottir F; Research Unit for Dietary Studies, The Parker Institute, Bispebjerg and Frederiksberg Hospital, Frederiksberg, Denmark.; The Department of Public Health, Section for General Practice, University of Copenhagen, Copenhagen, Denmark., Specht IO; Research Unit for Dietary Studies, The Parker Institute, Bispebjerg and Frederiksberg Hospital, Frederiksberg, Denmark.; The Department of Public Health, Section for General Practice, University of Copenhagen, Copenhagen, Denmark., Cohen A; Department for Congenital Disorders, Danish Center for Neonatal Screening, Statens Serum Institute, Copenhagen, Denmark., Heitmann BL; Research Unit for Dietary Studies, The Parker Institute, Bispebjerg and Frederiksberg Hospital, Frederiksberg, Denmark.; The Department of Public Health, Section for General Practice, University of Copenhagen, Copenhagen, Denmark.; The Boden Institute of Obesity, Nutrition, Exercise & Eating Disorders, The University of Sydney, Sydney, Australia., Kesmodel US; Department of Obstetrics and Gynecology, Aalborg University Hospital, Aalborg, Denmark.; Department of Obstetrics and Gynecology, Herlev University Hospital, Herlev, Denmark.
المصدر: Acta obstetricia et gynecologica Scandinavica [Acta Obstet Gynecol Scand] 2024 Jul; Vol. 103 (7), pp. 1329-1338. Date of Electronic Publication: 2024 Apr 18.
نوع المنشور: Journal Article; Comparative Study
اللغة: English
بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 0370343 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-0412 (Electronic) Linking ISSN: 00016349 NLM ISO Abbreviation: Acta Obstet Gynecol Scand Subsets: MEDLINE
أسماء مطبوعة: Publication: 2011- : Malden, MA : Wiley
Original Publication: Copenhagen : Munksgaard
مواضيع طبية MeSH: Fertilization in Vitro* , Cholecalciferol*/blood, Humans ; Infant, Newborn ; Female ; Denmark/epidemiology ; Pregnancy ; Male ; Adult ; Cohort Studies ; Registries ; Vitamin D Deficiency/epidemiology ; Vitamin D Deficiency/blood
مستخلص: Introduction: Sufficient levels of vitamin D have been associated with higher chances for both clinical pregnancy and live birth among women undergoing assisted reproductive techniques, whereas low levels of maternal vitamin D have been associated with preeclampsia and late miscarriage. In Denmark, subgroups at risk for low vitamin D levels, including neonates and toddlers, are recommended to use supplementation. The aim was to study the level of vitamin D 3 among neonates born after in vitro fertilization compared with neonates from the general population.
Material and Methods: In this cohort study a random sample of 1326 neonates representing the general population and 1200 neonates conceived by in vitro fertilization born in Denmark from 1995 to 2002 were identified from registries covering the whole Danish population. Information on use of assisted reproduction was collected from the Danish In Vitro Fertilization register, ICD-10 code: DZ358F. 25-Hydroxyvitamin D was measured from dried blood spots routinely collected by heel prick 48-72 h after birth and corrected according to the hematocrit fraction for capillary blood of neonates. Linear regression analysis was performed, both crude and adjusted, for predefined putative confounders, identified through directed acyclic graphs.
Results: Vitamin D 3 analysis could be performed from a total of 1105 neonates from the general population and 1072 neonates conceived by in vitro fertilization that were subsequently included in the study. The median vitamin D 3 was 24.0 nmol/L (interquartile range [IQR] 14.1-39.3) and 33.0 nmol/L (IQR 21.3-48.8) among neonates from the general population and neonates conceived by in vitro fertilization, respectively. The adjusted mean difference between neonates from the general population and those conceived by in vitro fertilization was 6.1 nmol/L (95% confidence interval 4.1-8.1).
Conclusions: In this study, children born after in vitro fertilization have a higher vitamin D 3 than a random sample of neonates in Denmark.
(© 2024 The Authors. Acta Obstetricia et Gynecologica Scandinavica published by John Wiley & Sons Ltd on behalf of Nordic Federation of Societies of Obstetrics and Gynecology (NFOG).)
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معلومات مُعتمدة: Herlev University Hospital; 11-116213 The Danish Council for Strategic Research; OCAY-18-774-OFIL Oak Foundation
فهرسة مساهمة: Keywords: in vitro fertilization; infertility; neonate; vitamin D
المشرفين على المادة: 1C6V77QF41 (Cholecalciferol)
تواريخ الأحداث: Date Created: 20240419 Date Completed: 20240612 Latest Revision: 20240614
رمز التحديث: 20240614
مُعرف محوري في PubMed: PMC11168265
DOI: 10.1111/aogs.14819
PMID: 38637997
قاعدة البيانات: MEDLINE
الوصف
تدمد:1600-0412
DOI:10.1111/aogs.14819