دورية أكاديمية
أعرض في EDS

Evidence and antibiotic resistance profiles of clinical Acinetobacter calcoaceticus-Acinetobacter baumannii (ACB) and non-ACB complex members in companion animals: A 2020-2022 retrospective study.

التفاصيل البيبلوغرافية
العنوان: Evidence and antibiotic resistance profiles of clinical Acinetobacter calcoaceticus-Acinetobacter baumannii (ACB) and non-ACB complex members in companion animals: A 2020-2022 retrospective study.
المؤلفون: Attili AR; School of Biosciences and Veterinary Medicine, University of Camerino, Via Circonvallazione 93/95, Macerata, Matelica 62024, Italy., Nocera FP; Department of Veterinary Medicine and Animal Production, University of Naples 'Federico II', Via F. Delpino n. 1, Naples 80137, Italy. Electronic address: francescapaola.nocera@unina.it., Sisto M; School of Biosciences and Veterinary Medicine, University of Camerino, Via Circonvallazione 93/95, Macerata, Matelica 62024, Italy., Linardi M; School of Biosciences and Veterinary Medicine, University of Camerino, Via Circonvallazione 93/95, Macerata, Matelica 62024, Italy., Gigli F; School of Biosciences and Veterinary Medicine, University of Camerino, Via Circonvallazione 93/95, Macerata, Matelica 62024, Italy., Ngwa VN; School of Veterinary Medicine and Sciences, University of Ngaoundéré, P.O. Box 454, Ngaoundéré, Cameroon., Fiorito F; Department of Veterinary Medicine and Animal Production, University of Naples 'Federico II', Via F. Delpino n. 1, Naples 80137, Italy., Cerracchio C; Department of Veterinary Medicine and Animal Production, University of Naples 'Federico II', Via F. Delpino n. 1, Naples 80137, Italy., Meligrana MCT; School of Biosciences and Veterinary Medicine, University of Camerino, Via Circonvallazione 93/95, Macerata, Matelica 62024, Italy., Bonacucina E; Veterinary Practitioner Freelance, Via Monte d'Aria, Castelraimondo, Macerata 62022, Italy., Cuteri V; School of Biosciences and Veterinary Medicine, University of Camerino, Via Circonvallazione 93/95, Macerata, Matelica 62024, Italy., De Martino L; Department of Veterinary Medicine and Animal Production, University of Naples 'Federico II', Via F. Delpino n. 1, Naples 80137, Italy.
المصدر: Comparative immunology, microbiology and infectious diseases [Comp Immunol Microbiol Infect Dis] 2024 Jun; Vol. 109, pp. 102185. Date of Electronic Publication: 2024 Apr 17.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 7808924 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1667 (Electronic) Linking ISSN: 01479571 NLM ISO Abbreviation: Comp Immunol Microbiol Infect Dis Subsets: MEDLINE
أسماء مطبوعة: Publication: Exeter : Elsevier Science Ltd
Original Publication: Oxford, Elmsford, N. Y., Pergamon Press.
مواضيع طبية MeSH: Acinetobacter Infections*/veterinary , Acinetobacter Infections*/microbiology , Acinetobacter Infections*/epidemiology , Acinetobacter Infections*/drug therapy , Anti-Bacterial Agents*/pharmacology , Acinetobacter baumannii*/drug effects , Acinetobacter baumannii*/genetics , Microbial Sensitivity Tests* , Drug Resistance, Multiple, Bacterial* , Dog Diseases*/microbiology , Dog Diseases*/drug therapy , Cat Diseases*/microbiology , Cat Diseases*/drug therapy, Animals ; Retrospective Studies ; Dogs ; Cats/microbiology ; Horses/microbiology ; Pets/microbiology ; Acinetobacter calcoaceticus/drug effects ; Acinetobacter calcoaceticus/genetics ; Horse Diseases/microbiology ; Horse Diseases/drug therapy
مستخلص: To evaluate the frequency of Acinetobacter spp., belonging to both Acinetobacter calcoaceticus-baumannii (ACB) and non-ACB complex, and their antibiotic resistance profiles in veterinary medicine, a three-year (2020-2022) retrospective study was carried out on sick companion animals. Epidemiological data from different clinical canine, feline, and equine samples, were acquired. For each strain, MALDI-TOF MS identification and susceptibility to a panel of 11 antibiotics, by Kirby-Bauer and E-test methods, were performed. Out of 628 bacteriological examinations, 2.5% resulted positive for strains belonging to Acinetobacter genus. Frequencies of 2.3%, 1.9%, and 3% were obtained from both in-visiting and hospitalized dogs, cats, and horses, respectively. Members of ACB-complex accounted for 50% of isolates. Since all strains resulted susceptible to aminoglycosides and polymyxins, no pandrug-resistant (PDR) species were recorded. While 12.5% A. baumannii resulted extensively-drug resistant (XDR), a higher percentage of multidrug-resistant strains was recorded among non-ACB strains (35.5%) than ACB strains (25%). Susceptibility was observed in the same percentage in both groups (62.5%). All ACB strains confirmed their intrinsic resistances. Non-ACB species showed lower resistances against antipseudomonal penicillins plus beta-lactamase inhibitors (P=0.1306), III generation cephalosporins (P=0.0547), and tetracyclines (P=0.0209) than ACB species. Carbapenem-resistance was observed for XDR A. baumannii (12.5%) and, in particular for MDR non-ACB complex members (25%). To our knowledge, A. lactucae represents the first description in two sick dogs in Italy. Furthermore, our results emphasize the role of non-ACB-complex species as important zoonotic pathogens, which could be reservoirs of clinically relevant resistance profiles.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.)
فهرسة مساهمة: Keywords: Acinetobacter bereziniae; Acinetobacter calcoaceticus-baumannii complex; Acinetobacter lactucae; Antibiotic resistance profiles; Cats; Dogs; Horses; Public health
تواريخ الأحداث: Date Created: 20240425 Date Completed: 20240519 Latest Revision: 20240519
رمز التحديث: 20240520
DOI: 10.1016/j.cimid.2024.102185
PMID: 38663213
قاعدة البيانات: MEDLINE
الوصف
تدمد:1878-1667
DOI:10.1016/j.cimid.2024.102185