دورية أكاديمية
أعرض في EDS

The Putative GATA Transcription Factor Sb GATA22 as a Novel Regulator of Dhurrin Biosynthesis.

التفاصيل البيبلوغرافية
العنوان: The Putative GATA Transcription Factor Sb GATA22 as a Novel Regulator of Dhurrin Biosynthesis.
المؤلفون: Rosati VC; School of Biological Sciences, Monash University, Wellington Road, Clayton, VIC 3800, Australia., Quinn AA; School of Biological Sciences, Monash University, Wellington Road, Clayton, VIC 3800, Australia., Gleadow RM; School of Biological Sciences, Monash University, Wellington Road, Clayton, VIC 3800, Australia.; Queensland Alliance for Agriculture & Food Innovation, The University of Queensland, St Lucia, QLD 4072, Australia., Blomstedt CK; School of Biological Sciences, Monash University, Wellington Road, Clayton, VIC 3800, Australia.
المصدر: Life (Basel, Switzerland) [Life (Basel)] 2024 Apr 03; Vol. 14 (4). Date of Electronic Publication: 2024 Apr 03.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101580444 Publication Model: Electronic Cited Medium: Print ISSN: 2075-1729 (Print) Linking ISSN: 20751729 NLM ISO Abbreviation: Life (Basel) Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI AG, 2011-
مستخلص: Cyanogenic glucosides are specialized metabolites produced by over 3000 species of higher plants from more than 130 families. The deployment of cyanogenic glucosides is influenced by biotic and abiotic factors in addition to being developmentally regulated, consistent with their roles in plant defense and stress mitigation. Despite their ubiquity, very little is known regarding the molecular mechanisms that regulate their biosynthesis. The biosynthetic pathway of dhurrin, the cyanogenic glucoside found in the important cereal crop sorghum ( Sorghum bicolor (L.) Moench), was described over 20 years ago, and yet no direct regulator of the biosynthetic genes has been identified. To isolate regulatory proteins that bind to the promoter region of the key dhurrin biosynthetic gene of sorghum, SbCYP79A1 , yeast one-hybrid screens were performed. A bait fragment containing 1204 base pairs of the SbCYP79A1 5' regulatory region was cloned upstream of a reporter gene and introduced into Saccharomyces cerevisiae . Subsequently, the yeast was transformed with library cDNA representing RNA from two different sorghum developmental stages. From these screens, we identified Sb GATA22, an LLM domain B-GATA transcription factor that binds to the putative GATA transcription factor binding motifs in the SbCYP79A1 promoter region. Transient assays in Nicotiana benthamiana show that Sb GATA22 localizes to the nucleus. The expression of SbGATA22 , in comparison with SbCYP79A1 expression and dhurrin concentration, was analyzed over 14 days of sorghum development and in response to nitrogen application, as these conditions are known to affect dhurrin levels. Collectively, these findings suggest that Sb GATA22 may act as a negative regulator of SbCYP79A1 expression and provide a preliminary insight into the molecular regulation of dhurrin biosynthesis in sorghum.
References: Plant Physiol. 2019 Jul;180(3):1336-1350. (PMID: 31123092)
Plant Direct. 2017 Oct 16;1(4):e00016. (PMID: 31245665)
Clin Pharm. 1986 Sep;5(9):737-41. (PMID: 3530615)
Annu Rev Plant Biol. 2014;65:155-85. (PMID: 24579992)
Plant Physiol. 2007 Dec;145(4):1144-54. (PMID: 18056864)
Plant Physiol. 2004 Apr;134(4):1718-32. (PMID: 15084732)
Curr Protoc Mol Biol. 2001 Aug;Chapter 12:Unit 12.12. (PMID: 18265084)
BMC Plant Biol. 2022 Jul 27;22(1):372. (PMID: 35896980)
Plant Physiol Biochem. 2013 Dec;73:83-92. (PMID: 24080394)
Front Plant Sci. 2015 Feb 23;6:90. (PMID: 25755661)
Plant Physiol. 2005 Sep;139(1):363-74. (PMID: 16126856)
Int J Mol Sci. 2021 Feb 18;22(4):. (PMID: 33670757)
Plant Physiol. 2012 Sep;160(1):332-48. (PMID: 22811435)
Biochem J. 2015 Aug 1;469(3):375-89. (PMID: 26205491)
J Exp Bot. 2022 Apr 18;73(8):2650-2665. (PMID: 35083483)
Bioinformatics. 2003 Jul 22;19(11):1439-40. (PMID: 12874059)
Phytochemistry. 1998 Jan;47(2):155-62. (PMID: 9431670)
Plant Mol Biol. 2005 Jul;58(5):699-720. (PMID: 16158244)
Plant J. 2011 Oct;68(2):273-86. (PMID: 21707799)
Front Plant Sci. 2017 Nov 13;8:1944. (PMID: 29181013)
Plant Biotechnol J. 2012 Jan;10(1):54-66. (PMID: 21880107)
Phytochemistry. 2004 Feb;65(3):293-306. (PMID: 14751300)
Mol Plant. 2017 Mar 6;10(3):498-515. (PMID: 27871810)
Annu Rev Plant Biol. 2022 May 20;73:123-148. (PMID: 35130446)
Plant Cell Physiol. 2016 Feb;57(2):373-86. (PMID: 26493517)
Front Plant Sci. 2023 Aug 04;14:1163357. (PMID: 37600205)
BMC Genomics. 2016 Dec 13;17(1):1021. (PMID: 27964718)
Plant Physiol. 2013 May;162(1):132-44. (PMID: 23548780)
Funct Plant Biol. 2018 Jun;45(7):705-718. (PMID: 32291046)
J Biol Chem. 1995 Feb 24;270(8):3506-11. (PMID: 7876084)
Mol Syst Biol. 2021 Nov;17(11):e10625. (PMID: 34816587)
Plant Physiol. 2014 Sep;166(1):293-305. (PMID: 25077795)
Plant Direct. 2018 Feb 26;2(2):e00038. (PMID: 31245705)
J Mol Biol. 2010 Feb 5;395(5):937-49. (PMID: 19962994)
Annu Rev Plant Physiol Plant Mol Biol. 1998 Jun;49:525-555. (PMID: 15012245)
Planta. 2021 Nov 11;254(6):119. (PMID: 34762174)
Mol Plant. 2016 Sep 6;9(9):1272-1285. (PMID: 27373216)
Plant Physiol. 2012 Jan;158(1):423-38. (PMID: 22065421)
Plant Physiol. 1989 Aug;90(4):1552-9. (PMID: 16666964)
Arch Biochem Biophys. 1995 Oct 20;323(1):177-86. (PMID: 7487064)
Proc Natl Acad Sci U S A. 2007 Nov 20;104(47):18848-53. (PMID: 18003897)
Nucleic Acids Res. 1989 Mar 25;17(6):2362. (PMID: 2468132)
Cell. 2014 Sep 11;158(6):1431-1443. (PMID: 25215497)
Science. 2019 Jun 14;364(6445):1095-1098. (PMID: 31197015)
BMC Genomics. 2022 Aug 2;23(1):549. (PMID: 35918632)
Plants (Basel). 2020 Dec 17;9(12):. (PMID: 33348715)
Acta Biochim Pol. 2006;53(2):289-98. (PMID: 16582986)
Plant J. 2018 Jun;94(6):1109-1125. (PMID: 29659075)
Plant Physiol. 2002 Jul;129(3):1222-31. (PMID: 12114576)
Plant Biol (Stuttg). 2023 Jun;25(4):498-508. (PMID: 36992539)
Theor Appl Genet. 2022 Mar;135(3):1037-1047. (PMID: 35001177)
Bioinformatics. 2009 May 1;25(9):1189-91. (PMID: 19151095)
Methods. 2012 Aug;57(4):441-7. (PMID: 22884952)
Nucleic Acids Res. 2016 Jan 4;44(D1):D1154-60. (PMID: 26476450)
Endocrinology. 2002 Oct;143(10):3963-73. (PMID: 12239108)
J Chem Ecol. 2002 Jul;28(7):1301-13. (PMID: 12199497)
EMBO J. 1999 May 17;18(10):2812-22. (PMID: 10329627)
Nucleic Acids Res. 2004 Mar 19;32(5):1792-7. (PMID: 15034147)
Plant Mol Biol. 1998 Feb;36(3):393-405. (PMID: 9484480)
Plant Cell. 2016 Mar;28(3):646-60. (PMID: 26917680)
Nucleic Acids Res. 2017 Jan 4;45(D1):D1040-D1045. (PMID: 27924042)
Plant Physiol. 2016 Apr;170(4):2295-311. (PMID: 26829982)
PLoS One. 2011;6(11):e26765. (PMID: 22102866)
معلومات مُعتمدة: LP100100434 Australian Research Council; DP130101049 Australian Research Council
فهرسة مساهمة: Keywords: GATA transcription factor; cyanogenesis; cyanogenic glucosides; regulation; specialized metabolites
تواريخ الأحداث: Date Created: 20240427 Latest Revision: 20240429
رمز التحديث: 20240429
مُعرف محوري في PubMed: PMC11051066
DOI: 10.3390/life14040470
PMID: 38672741
قاعدة البيانات: MEDLINE
الوصف
تدمد:2075-1729
DOI:10.3390/life14040470