دورية أكاديمية
Respiratory Syncytial Virus Hospitalizations Associated With Social Vulnerability by Census Tract: An Opportunity for Intervention?
| العنوان: | Respiratory Syncytial Virus Hospitalizations Associated With Social Vulnerability by Census Tract: An Opportunity for Intervention? |
|---|---|
| المؤلفون: | Thomas CM; Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.; Communicable and Environmental Diseases and Emergency Preparedness Division, Tennessee Department of Health, Nashville, Tennessee, USA., Raman R; Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Schaffner W; Department of Health Policy, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Division of Infectious Diseases, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Markus TM; Department of Health Policy, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Ndi D; Department of Health Policy, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Fill MA; Communicable and Environmental Diseases and Emergency Preparedness Division, Tennessee Department of Health, Nashville, Tennessee, USA., Dunn JR; Communicable and Environmental Diseases and Emergency Preparedness Division, Tennessee Department of Health, Nashville, Tennessee, USA., Talbot HK; Department of Health Policy, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Division of Infectious Diseases, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA. |
| المصدر: | Open forum infectious diseases [Open Forum Infect Dis] 2024 Mar 29; Vol. 11 (5), pp. ofae184. Date of Electronic Publication: 2024 Mar 29 (Print Publication: 2024). |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Published by Oxford University Press on behalf of the Infectious Diseases Society of America Country of Publication: United States NLM ID: 101637045 Publication Model: eCollection Cited Medium: Print ISSN: 2328-8957 (Print) Linking ISSN: 23288957 NLM ISO Abbreviation: Open Forum Infect Dis Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: Cary, NC : Published by Oxford University Press on behalf of the Infectious Diseases Society of America, [2014]- |
| مستخلص: | Background: Respiratory syncytial virus (RSV) can cause hospitalization in young children and older adults. With vaccines and monoclonal antibody prophylaxis increasingly available, identifying social factors associated with severe illnesses can guide mitigation efforts. Methods: Using data collected by the RSV Hospitalization Surveillance Network from 2016 to 2023, we identified RSV hospitalizations in Tennessee. We linked hospitalization information (eg, patient demographic characteristics and outcome) with population-level variables (eg, social vulnerability and health care insurance coverage) from publicly available data sets using census tract of residence. Hospitalization incidence was calculated and stratified by period (2016-2020 and 2020-2023). We modeled social vulnerability effect on hospitalization incidence using Poisson regression. Results: Among 2687 RSV hospitalizations, there were 677 (25.2%) intensive care unit admissions and 38 (1.4%) deaths. The highest RSV hospitalization incidences occurred among children aged <5 years and adults aged ≥65 years: 272.8 per 100 000 person-years (95% CI, 258.6-287.0) and 60.6 (95% CI, 56.0-65.2), respectively. Having public health insurance was associated with higher hospitalization incidence as compared with not having public insurance: 60.5 per 100 000 person-years (95% CI, 57.6-63.4) vs 14.3 (95% CI, 13.4-15.2). Higher hospitalization incidence was associated with residing in a census tract in the most socially vulnerable quartile vs the least vulnerable quartile after adjusting for age, sex, and period (incidence rate ratio, 1.4; 95% CI, 1.3-1.6). Conclusions: RSV hospitalization was associated with living in more socially vulnerable census tracts. Population measures of social vulnerability might help guide mitigation strategies, including vaccine and monoclonal antibody promotion and provision to reduce RSV hospitalization. Competing Interests: Potential conflicts of interest. M.-M. A. F. reports support from the Council of State and Territorial Epidemiologists (CSTE) to attend the CSTE annual meeting and from Johns Hopkins University to attend the Johns Hopkins Center for Health Security Emerging Leaders in Biosecurity Summer Research Symposium; service as an external member on the University of Tennessee's One Health Initiative Board; and participation as a CSTE representative to the Advisory Committee on Immunization Practices’ Adult Immunization Schedules and General Best Practices Work Groups. W. S. reports serving as the medical director of the National Foundation for Infectious Diseases. H. K. T. reports grant and contract funding from the CDC. All other authors report no potential conflicts. (Published by Oxford University Press on behalf of Infectious Diseases Society of America 2024.) |
| References: | MMWR Morb Mortal Wkly Rep. 2023 Jul 21;72(29):793-801. (PMID: 37471262) BMC Infect Dis. 2021 Mar 23;21(1):293. (PMID: 33757443) JAMA Health Forum. 2023 Jun 2;4(6):e231582. (PMID: 37389862) Pediatrics. 2023 Aug 1;152(2):. (PMID: 37449336) MMWR Morb Mortal Wkly Rep. 2020 Oct 23;69(42):1535-1541. (PMID: 33090977) Pediatrics. 2021 Apr;147(4):. (PMID: 33737374) J Biomed Inform. 2019 Jul;95:103208. (PMID: 31078660) Influenza Other Respir Viruses. 2017 Nov;11(6):479-488. (PMID: 28872776) N Engl J Med. 2009 Feb 5;360(6):588-98. (PMID: 19196675) J Biomed Inform. 2009 Apr;42(2):377-81. (PMID: 18929686) MMWR Morb Mortal Wkly Rep. 2023 Aug 25;72(34):920-925. (PMID: 37616235) Pediatrics. 2004 Oct;114(4):e437-44. (PMID: 15466069) N Engl J Med. 2023 Sep 14;389(11):1053-1055. (PMID: 37703563) Public Health Rep. 2019 May/Jun;134(3):241-248. (PMID: 30912998) J Infect Dis. 2024 Mar 1;229(Supplement_1):S61-S69. (PMID: 37797317) Clin Infect Dis. 2019 Jul 2;69(2):197-203. (PMID: 30452608) MMWR Morb Mortal Wkly Rep. 2023 Oct 13;72(41):1115-1122. (PMID: 37824423) Clin Infect Dis. 2023 May 3;76(9):1615-1625. (PMID: 36611252) Circ Cardiovasc Qual Outcomes. 2022 Aug;15(8):e008612. (PMID: 35862003) Pediatrics. 2023 Jul 1;152(1):. (PMID: 37357729) Clin Infect Dis. 2022 Mar 23;74(6):1004-1011. (PMID: 34244735) PLoS One. 2017 Aug 10;12(8):e0182321. (PMID: 28797053) MMWR Morb Mortal Wkly Rep. 2021 Jun 04;70(22):818-824. (PMID: 34081685) Am J Transplant. 2021 Oct;21(10):3481-3486. (PMID: 34624182) Vaccines (Basel). 2022 Jan 29;10(2):. (PMID: 35214670) Epidemiol Infect. 2022 Feb 02;150:e45. (PMID: 35105415) N Engl J Med. 2023 Apr 20;388(16):1465-1477. (PMID: 37018468) MMWR Morb Mortal Wkly Rep. 2023 Apr 07;72(14):355-361. (PMID: 37022977) Am J Epidemiol. 2013 Apr 1;177(7):656-65. (PMID: 23436899) Prev Med. 2022 Oct;163:107226. (PMID: 36029925) MMWR Morb Mortal Wkly Rep. 2022 Oct 28;71(43):1359-1365. (PMID: 36301738) |
| فهرسة مساهمة: | Keywords: ethnicity; insurance; race; social determinant of health; socioeconomic status |
| تواريخ الأحداث: | Date Created: 20240429 Latest Revision: 20240603 |
| رمز التحديث: | 20240603 |
| مُعرف محوري في PubMed: | PMC11055400 |
| DOI: | 10.1093/ofid/ofae184 |
| PMID: | 38680605 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder كن أول من يترك تعليقا!