دورية أكاديمية
Hepatitis B vaccine birth dose coverage among hepatitis B-exposed and hepatitis B-unexposed infants: evidence from the Healthy Beginning Initiative program in Benue State, Nigeria.
| العنوان: | Hepatitis B vaccine birth dose coverage among hepatitis B-exposed and hepatitis B-unexposed infants: evidence from the Healthy Beginning Initiative program in Benue State, Nigeria. |
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| المؤلفون: | Olakunde BO; Department of Community Prevention and Care Services, National Agency for the Control of AIDS, Abuja, Nigeria.; Center for Translation and Implementation Research, University of Nigeria, Nsukka, Enugu, Nigeria., Itanyi IU; Center for Translation and Implementation Research, University of Nigeria, Nsukka, Enugu, Nigeria.; Department of Community Medicine, College of Medicine, University of Nigeria, Nsukka, Enugu, Nigeria., Onyeka TC; Center for Translation and Implementation Research, University of Nigeria, Nsukka, Enugu, Nigeria.; Department of Anesthesia/Pain and Palliative Care Unit, College of Medicine, University of Nigeria, Nsukka, Nigeria., Paintsil E; Department of Pediatrics, Yale School of Medicine, New Haven, CT 06510, USA.; Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT 06510, USA.; Department of Pharmacology, Yale School of Medicine, New Haven, CT, USA., Torpey K; Department of Population, Family and Reproductive Health, School of Public Health, University of Ghana, Legon-Accra, Ghana., Lasebikan N; Center for Translation and Implementation Research, University of Nigeria, Nsukka, Enugu, Nigeria.; Department of Radiation Medicine, College of Medicine, University of Nigeria, Nsukka, Enugu, Nigeria., Chigbu CO; Center for Translation and Implementation Research, University of Nigeria, Nsukka, Enugu, Nigeria.; Department of Obstetrics and Gynaecology, College of Medicine, University of Nigeria, Nsukka, Enugu, Nigeria., Ezeanolue EE; Center for Translation and Implementation Research, University of Nigeria, Nsukka, Enugu, Nigeria.; Department of Paediatrics, College of Medicine, University of Nigeria, Nsukka, Enugu, Nigeria.; Healthy Sunrise Foundation, Nevada, USA. |
| المصدر: | The Pan African medical journal [Pan Afr Med J] 2024 Feb 14; Vol. 47, pp. 67. Date of Electronic Publication: 2024 Feb 14 (Print Publication: 2024). |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: African Field Epidemiology Network Country of Publication: Uganda NLM ID: 101517926 Publication Model: eCollection Cited Medium: Internet ISSN: 1937-8688 (Electronic) NLM ISO Abbreviation: Pan Afr Med J Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Kampala, Uganda : African Field Epidemiology Network |
| مواضيع طبية MeSH: | Hepatitis B*/prevention & control , Hepatitis B*/epidemiology , Hepatitis B Vaccines*/administration & dosage , Vaccination Coverage*/statistics & numerical data , Pregnancy Complications, Infectious*/prevention & control, Humans ; Nigeria ; Female ; Pregnancy ; Adult ; Young Adult ; Infant, Newborn ; Infant ; Infectious Disease Transmission, Vertical/prevention & control ; Immunization Programs ; Cohort Studies ; Adolescent ; Vaccination/statistics & numerical data |
| مستخلص: | Introduction: Nigeria offers universal hepatitis B birth-dose vaccine (HepB-BD) for the prevention and control of hepatitis B (HepB). While prior studies suggest low coverage of HepB-BD in Nigeria, there is a paucity of evidence on the association between the uptake of HepB-BD and maternal HepB status. This study aimed to determine HepB-BD coverage and the associated factors among infants of HepB-positive and -negative women in Nigeria. Methods: the study was a secondary analysis of data from the Healthy Beginning Initiative program conducted between June 2016 and October 2018 in Benue State, Nigeria. The analysis was restricted to data from a cohort of 6269 mothers who had HepB screening during pregnancy and completed the HepB infant immunization question in the post-delivery survey. The association between the coverage of HepB-BD and maternal HepB status, sociodemographic characteristics, and obstetric factors were determined using crude and adjusted relative risks. Results: about 10% of the women tested HepB positive. The coverage of HepB-BD was 64% (63.2% among infants of HepB-positive mothers and 63.8% among HepB-negative mothers). The likelihood of infants of HepB-positive mothers receiving HepB-BD was not significantly different from infants of HepB-negative mothers (aRR=0.97, 95%CI= 0.92-1.04). Among HepB-positive mothers, infants of mothers younger than 20 years (aRR=1.49, 95%CI=1.03-2.16) or those who received antenatal care (aRR=1.41, 95%CI=1.16-1.71) were more likely to receive HepB-BD, while mothers with no previous pregnancies (aRR=0.73, 95%CI=0.59-0.91) were less likely to receive HepB-BD. Among HepB-negative mothers, infants of less-educated mothers were less likely to receive HepB-BD (aRR=0.96, 95%CI=0.92-0.99), whereas infants of mothers who received antenatal care (aRR=1.23, 95%CI=1.16-1.31) or had an institutional delivery were more likely (aRR=1.29, 95%CI=1.23-1.36) to receive HepB-BD. Conclusion: our findings highlight the need to improve HepB-BD uptake, particularly among HepB-exposed infants who are at risk of perinatal transmission of HepB. Competing Interests: The authors declare no competing interests. (Copyright: Babayemi Oluwaseun Olakunde et al.) |
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| فهرسة مساهمة: | Keywords: Infants; immunization; perinatal transmission; viral hepatitis |
| المشرفين على المادة: | 0 (Hepatitis B Vaccines) |
| تواريخ الأحداث: | Date Created: 20240429 Date Completed: 20240429 Latest Revision: 20240430 |
| رمز التحديث: | 20240430 |
| مُعرف محوري في PubMed: | PMC11055182 |
| DOI: | 10.11604/pamj.2024.47.67.40466 |
| PMID: | 38681098 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1937-8688 |
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| DOI: | 10.11604/pamj.2024.47.67.40466 |