دورية أكاديمية
Near-infrared fluorescent indolizine-dicyanomethylene-4H-pyran hybrids for viscosity imaging in living cells.
| العنوان: | Near-infrared fluorescent indolizine-dicyanomethylene-4H-pyran hybrids for viscosity imaging in living cells. |
|---|---|
| المؤلفون: | Duan J; College of Science, Nanjing Forestry University, Nanjing 210037, China., Ouyang X; College of Science, Nanjing Forestry University, Nanjing 210037, China., Jiang Z; School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China., Liu Z; Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, Nanjing Forestry University, Nanjing 210037, China., Wang X; College of Science, Nanjing Forestry University, Nanjing 210037, China. Electronic address: xqwang@njfu.edu.cn. |
| المصدر: | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy [Spectrochim Acta A Mol Biomol Spectrosc] 2024 Aug 05; Vol. 316, pp. 124330. Date of Electronic Publication: 2024 Apr 23. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: England NLM ID: 9602533 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3557 (Electronic) Linking ISSN: 13861425 NLM ISO Abbreviation: Spectrochim Acta A Mol Biomol Spectrosc Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Original Publication: [Kidlington, Oxford, U.K. ; Tarrytown, NY] : Pergamon, c1994- |
| مواضيع طبية MeSH: | Indolizines*/chemistry , Indolizines*/chemical synthesis , Fluorescent Dyes*/chemistry , Fluorescent Dyes*/chemical synthesis , Pyrans*/chemistry, Viscosity ; Humans ; Spectrometry, Fluorescence ; HeLa Cells ; Spectroscopy, Near-Infrared/methods |
| مستخلص: | The development of near-infrared organic fluorescent dyes with tunable emission profiles is highly required in the field of biological sensing and imaging. In this paper, we designed and synthesized two organic fluorescent dyes, DCM-1 and DCM-2, through the hybridization of indolizine and dicyanomethylene-4H-pyran skeleton. These two compounds show near-infrared fluorescence with emission maximum approximately at 640 and 680 nm, respectively. Notably, both DCM-1 and DCM-2 have specific responses to viscosity without being interfered by biological relevant species. Cell experiments demonstrate that DCM-1 and DCM-2 can detect dynamic changes in viscosity within living cells, suggesting their potential applications in chemical biology research. Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (Copyright © 2024 Elsevier B.V. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Dicyanomethylene-4H-pyran; Indolizine; NIR emission; Organic fluorescent dyes; Viscosity |
| المشرفين على المادة: | 0 (Indolizines) 0 (Fluorescent Dyes) 0 (Pyrans) 274-40-8 (indolizine) |
| تواريخ الأحداث: | Date Created: 20240430 Date Completed: 20240513 Latest Revision: 20240513 |
| رمز التحديث: | 20240514 |
| DOI: | 10.1016/j.saa.2024.124330 |
| PMID: | 38685160 |
| قاعدة البيانات: | MEDLINE |
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