دورية أكاديمية

Longitudinal analysis of microcirculatory parameters in gingival tissues after tooth extraction in patients with different risk profiles for wound healing disorders - a pilot study.

التفاصيل البيبلوغرافية
العنوان: Longitudinal analysis of microcirculatory parameters in gingival tissues after tooth extraction in patients with different risk profiles for wound healing disorders - a pilot study.
المؤلفون: Mayr A; Department of Orthodontics, University Hospital Bonn, Medical Faculty, Bonn, Germany., Ciper N; Center for Dental, Oral and Maxillofacial Medicine, University Hospital Bonn, Medical Faculty, Bonn, Germany., Wahl G; Center for Dental, Oral and Maxillofacial Medicine, University Hospital Bonn, Medical Faculty, Bonn, Germany., Wildenhof J; Private Clinic Schloss Schellenstein, Olsberg, Germany., Frede S; Department of Anaesthesiology, University Hospital Bonn, Medical Faculty, Bonn, Germany., Kirschneck C; Department of Orthodontics, University Hospital Bonn, Medical Faculty, Bonn, Germany., Jäger A; Department of Orthodontics, University Hospital Bonn, Medical Faculty, Bonn, Germany., Götz W; Department of Orthodontics, University Hospital Bonn, Medical Faculty, Bonn, Germany., Beisel-Memmert S; Department of Orthodontics, University Hospital Bonn, Medical Faculty, Bonn, Germany. Svenja.Memmert@ukbonn.de.
المصدر: Clinical oral investigations [Clin Oral Investig] 2024 May 08; Vol. 28 (6), pp. 303. Date of Electronic Publication: 2024 May 08.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 9707115 Publication Model: Electronic Cited Medium: Internet ISSN: 1436-3771 (Electronic) Linking ISSN: 14326981 NLM ISO Abbreviation: Clin Oral Investig Subsets: MEDLINE
أسماء مطبوعة: Publication: Berlin : Springer-Verlag
Original Publication: Berlin : Springer, c1997-
مواضيع طبية MeSH: Microcirculation* , Wound Healing*/physiology , Gingiva*/blood supply , Tooth Extraction* , Laser-Doppler Flowmetry* , Periodontitis*, Humans ; Pilot Projects ; Male ; Female ; Middle Aged ; Adult ; Longitudinal Studies ; Risk Factors ; Oxygen Saturation ; Smoking ; Aged
مستخلص: Objectives: We aimed to establish a risk profile for intraoral wound healing disorders based on measurements of microcirculation in gingival tissues.
Materials and Methods: Oxygen saturation (SO 2) and blood flow in gingival tissues were measured with tissue spectrometry and laser doppler spectroscopy in 37 patients before/after tooth extractions. Patients were assigned to four groups: anamnestically and periodontally healthy patients (n = 7), anamnestically healthy but suffering from periodontitis (n = 10), anamnestically healthy but smoking and suffering from periodontitis (n = 10) and suffering from diabetes and periodontitis (n = 10). Measurements were performed at three different time points: Baseline measurement (T0), one day post extractionem (p.e.) (T1) and seven days p.e. (T2).
Results: Baseline SO 2 values were higher in control patients (p = .038). This effect was most evident in comparison to smokers suffering from periodontitis (p = .042), followed by diabetics suffering from periodontitis (p = .09). An opposite trend was seen for blood flow. Patients suffering from periodontitis demonstrated higher blood flow values (p = .012). Five patients, which belonged to the group of smokers suffering from periodontitis, showed clinically a delayed wound healing.
Conclusion: Differences in SO 2 and blood flow of gingival tissue could be detected in different groups of patients with existing periodontitis compared to control patients.
Clinical Relevance: Lower baseline SO 2 values could be a warning signal for possible wound healing disorders after oral surgery.
(© 2024. The Author(s).)
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فهرسة مساهمة: Keywords: Microcirculation; Periodontitis; Spectrophotometry; Tooth extraction; Wound healing disorder
تواريخ الأحداث: Date Created: 20240507 Date Completed: 20240507 Latest Revision: 20240703
رمز التحديث: 20240703
مُعرف محوري في PubMed: PMC11076346
DOI: 10.1007/s00784-024-05686-3
PMID: 38714559
قاعدة البيانات: MEDLINE