دورية أكاديمية
Low-profile mechanical thrombectomy devices for large vessel occlusion in pediatric ischemic stroke.
| العنوان: | Low-profile mechanical thrombectomy devices for large vessel occlusion in pediatric ischemic stroke. |
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| المؤلفون: | Oushy S; Department of Neurosurgery, Harvard Medical School, Boston, Massachusetts, USA.; Department of Neurosurgery, Mayo Clinic, Rochester, Minnesota, USA., Garton A; Neurosurgery, NewYork-Presbyterian Hospital/Weill Cornell Medical Center, New York, New York, USA., Orbach DB; Department of Neurointerventional Radiology, Harvard Medical School, Boston, Massachusetts, USA., See AP; Department of Neurosurgery, Harvard Medical School, Boston, Massachusetts, USA pokmeng.see@childrens.harvard.edu. |
| المصدر: | Journal of neurointerventional surgery [J Neurointerv Surg] 2024 May 06. Date of Electronic Publication: 2024 May 06. |
| Publication Model: | Ahead of Print |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: BMJ Publishing Group Country of Publication: England NLM ID: 101517079 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1759-8486 (Electronic) Linking ISSN: 17598478 NLM ISO Abbreviation: J Neurointerv Surg Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: London : BMJ Publishing Group, c2009- |
| مستخلص: | Background: Mechanical thrombectomy (MT) is a well-established treatment modality for large vessel occlusion (LVO) in adults, but there are limited data in the pediatric population. The rarity of the condition makes prospective trial design difficult, and therefore evaluation of MT devices and outcomes is sparse. In pediatric LVO cases, some newer devices may be appropriate for use in revascularization procedures. Furthermore, illustrative specific device-access combinations have rarely been presented in young patients under the age of 5 years. Methods: This was a single institution experience in intracranial MT procedures for pediatric acute ischemic stroke (AIS). A given procedure was included if there was an attempt at MT between 2015 and 2023. Results: Sixteen endovascular procedures were performed in 15 patients with AIS, with a mean age of 7.4 years; eight patients were <5 years of age. MT was attempted in 15/16 (93.7%) procedures, including 11 (73.3%) in the anterior circulation and four (26.7%) in the posterior circulation; one case recanalized after medical treatment. The most common MT techniques were combined aspiration with a stentriever (n=10, 66.7%) and aspiration alone (n=3, 20%). Traditional stentrievers (4-6 mm) were used in seven cases and low-profile stentrievers in four cases. Improved reperfusion was achieved in all low-profile stentriever cases. Reperfusion of modified Thrombolysis in Cerebral Infaction ≥2b was obtained in 73.3% of cases, including 72.7% of those in which a stentriever was used. Conclusions: Low-profile thrombectomy devices may achieve similar revascularization results to other approaches in challenging clinical scenarios observed in younger children. Competing Interests: Competing interests: None declared. (© Author(s) (or their employer(s)) 2024. No commercial re-use. See rights and permissions. Published by BMJ.) |
| فهرسة مساهمة: | Keywords: Device; Pediatrics; Stroke; Technique; Thrombectomy |
| تواريخ الأحداث: | Date Created: 20240508 Latest Revision: 20240508 |
| رمز التحديث: | 20240509 |
| DOI: | 10.1136/jnis-2024-021574 |
| PMID: | 38719443 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1759-8486 |
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| DOI: | 10.1136/jnis-2024-021574 |