دورية أكاديمية
Early induction of luteolysis in a timed AI protocol increases reproductive performance in beef cows.
| العنوان: | Early induction of luteolysis in a timed AI protocol increases reproductive performance in beef cows. |
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| المؤلفون: | Silva EP; Unidade de Reprodução de Bovinos, Departamento de Medicina Animal, Faculdade de Veterinária, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil; Department of Animal and Dairy Sciences, University of Wisconsin-Madison, Madison, WI, United States; Programa de Pós-Graduação em Medicina Veterinária, Universidade Federal de Santa Maria (UFSM), Santa Maria, RS, Brazil., Antoniazzi AQ; Programa de Pós-Graduação em Medicina Veterinária, Universidade Federal de Santa Maria (UFSM), Santa Maria, RS, Brazil., Borges JBS; Unidade de Reprodução de Bovinos, Departamento de Medicina Animal, Faculdade de Veterinária, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil., Monteiro PLJ; Department of Animal and Dairy Sciences, University of Wisconsin-Madison, Madison, WI, United States; Department of Large Animal Clinical Sciences, University of Florida, Gainesville, FL 32608 United States., Machado AB; Unidade de Reprodução de Bovinos, Departamento de Medicina Animal, Faculdade de Veterinária, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil., Dias MM; Unidade de Reprodução de Bovinos, Departamento de Medicina Animal, Faculdade de Veterinária, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil., Portela Junior VVM; Programa de Pós-Graduação em Medicina Veterinária, Universidade Federal de Santa Maria (UFSM), Santa Maria, RS, Brazil., Wiltbank MC; Department of Animal and Dairy Sciences, University of Wisconsin-Madison, Madison, WI, United States. Electronic address: Wiltbank@wisc.edu. |
| المصدر: | Domestic animal endocrinology [Domest Anim Endocrinol] 2024 Jul; Vol. 88, pp. 106853. Date of Electronic Publication: 2024 May 03. |
| نوع المنشور: | Journal Article; Randomized Controlled Trial, Veterinary |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: United States NLM ID: 8505191 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0054 (Electronic) Linking ISSN: 07397240 NLM ISO Abbreviation: Domest Anim Endocrinol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Stoneham, Ma : Elsevier Original Publication: [Auburn, Ala.] : Domendo, Inc., c1984- |
| مواضيع طبية MeSH: | Insemination, Artificial*/veterinary , Dinoprost*/pharmacology , Dinoprost*/administration & dosage , Luteolysis*/drug effects , Progesterone*/pharmacology , Progesterone*/administration & dosage , Progesterone*/blood, Animals ; Cattle/physiology ; Female ; Pregnancy ; Estrus Synchronization/methods ; Estradiol/pharmacology ; Estradiol/administration & dosage ; Estradiol/analogs & derivatives ; Cloprostenol/pharmacology ; Cloprostenol/administration & dosage |
| مستخلص: | The aim of this study was to produce a longer proestrus by early administration of prostaglandin F2α (PGF) in a timed artificial insemination (TAI) protocol in non-suckling Bos taurus (Angus crossbreed) beef cows. On day 0, cows (n = 489) were treated with an intravaginal 1 g progesterone (P4) device and 2 mg of estradiol benzoate. On day 7, cows were randomized into two groups: PGF7(n = 244; 500 µg of sodium cloprostenol 24 h before P4 device removal) or PFG8 (n = 245; 500 µg of sodium cloprostenol at P4 device removal). On day 8, P4 device was removed and cows received 0.5 mg of estradiol cypionate. All cows were submitted to TAI on day 10 (48-50 hours after P4 device removal). Cows treated with PGF on day 7 had greater expression of estrus (91.3 vs 79.1 %; P = 0.0011), regardless of CL presence at beginning of the protocol. Cows from PGF7 group had lower circulating P4 concentrations on day 8 in comparison with PGF8 treated cows (1.86 vs 2.99 ng/mL; P < 0.001). However, preovulatory follicle diameter did not differ among treatments at TAI (11.9 vs 11.8 mm; P = 0.7881). Pregnancy per TAI (P/TAI) was greater for PGF7 (63.9 vs 50.6 %; P = 0.0114) than PGF8 treated cows. In cows with follicles <8.5 mm at TAI, expression of estrus (33.3 vs 26.6 %; P = 0.6427) and P/TAI (40 vs 26.6 %; P = 0.3657) were low in both PGF7 and PGF8 treated cows, respectively. In cows with medium follicle size (8.5 to 11.9 mm) PGF7 treated cows had greater expression of estrus (90.5 vs 80 %; P = 0.033) and P/TAI (62.2 vs 49 %; P = 0.053). In cows with follicles >12 mm, expression of estrus was greater for PGF7 than PGF8 treated cows (99.1 vs 93.3 %; P = 0.045), however P/TAI did not differ (68.2 vs 59 %; P = 0.149). In cows with P4 < 1.99 ng/mL on day 8, expression of estrus was similar between PGF7 and PGF8 treated cows (92.6 vs 90.4 %; P = 0.53), and P/TAI tended to be greater for PGF7 than PGF8 treated cows (63 vs 52.1 % P = 0.076). However, in cows with P4 > 2 ng/mL PGF7 cows had higher expression of estrus (89 vs 67.5 %; P = 0.0005) and P/TAI (64.8 vs 48.7 %; P = 0.021) than PGF8. Thus, increasing the proestrous period by inducing luteolysis 24 hours earlier than removing the P4 intravaginal device enhanced fertility in non-suckling cyclic beef cows by increasing expression of estrus and P/TAI. (Copyright © 2024 Elsevier Inc. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Estrus; Luteolysis; Prostaglandin; Timed AI |
| المشرفين على المادة: | B7IN85G1HY (Dinoprost) 4G7DS2Q64Y (Progesterone) 4TI98Z838E (Estradiol) 4208238832 (Cloprostenol) |
| تواريخ الأحداث: | Date Created: 20240510 Date Completed: 20240605 Latest Revision: 20240605 |
| رمز التحديث: | 20240606 |
| DOI: | 10.1016/j.domaniend.2024.106853 |
| PMID: | 38729096 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1879-0054 |
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| DOI: | 10.1016/j.domaniend.2024.106853 |